Penn Medicine Provider

About me

  • Associate Director, Center for Molecular Studies in Digestive and Liver Diseases
  • T. Grier Miller Professor of Medicine

Insurance accepted

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Qualifications and experience

Treatments and Conditions

My research

Chen YH, Yeung F, Lacey KA, Zaldana K, Lin JD, Bee GCW, McCauley C, Barre RS, Liang SH, Hansen CB, Downie AE, Tio K, Weiser JN, Torres VJ, Bennett RJ, Loke P*, Graham AL*, and Cadwell K. Rewilding of laboratory mice remedies reduced granulopoiesis and sustains enhanced immunity through intestinal fungal colonization. , Science Immunology: 2023


Matsuzawa-Ishimoto Y, Yao X, Koide A, Ueberheide BM, Axelrad JE, Reis BS, Parsa R, Neil JA, Devlin JC, Rudensky E, Dewan MZ, Cammer M, Blumberg RS, Ding Y, Ruggles KV, Mucida D, Koide S* and Cadwell K*. Gamma delta IEL effector API5 masks genetic susceptibility to Paneth cell death. , Nature, 610(7932): 2022,547-554


Ching KL, de Vries M, Gago J, Dancel-Manning K, Sall J, Rice WJ, Barnett C, Liang FX, Thorpe LE, Shopsin B, Segal LN, Dittmann M*, Torres VJ*, Cadwell K* ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection. , PLoS Biol, 20(9): 2022,e3001754


Venzon M, Das R, Luciano DJ, Burnett J, Park HS, Devlin JC, Kool ET, Belasco JG, Hubbard EJA*, Cadwell K* Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes. , Cell Host & Microbe, 5(22): 2022,S1931-3128


Dallari S, Heaney T, Rosas-Villegas A, Neil JA, SY, Brown JJ, Urbanek K, Herrmann C, Depledge DP, Dermody TS, Cadwell K. Enteric viruses evoke broad host immune responses resembling bacterial microbiome , Cell Host & Microbe., 29(6): 2021,1014-1029


Yeung F, Chen YH, Lin JD, Leung JM, McCauley C, Devlin JC, Hansen C, Cronkite A, Stephen J, Drake-Dunn C, Fulmer Y, Shopsin B, Ruggles KV, Round JL, Loke P*, Graham AL*, Cadwell K*. Altered immunity of laboratory mice in the natural environment is associated with fungal colonization , Cell Host & Microbe, 27(5): 2020,809-822.e6


Keller MD, Ching KL, Liang FX, Dhabaria A, Tam K, Ueberheide BM, Unutmaz D, Torres VJ*, Cadwell K Decoy exosomes provide protection against bacterial toxins , Nature, 579(7798): 2020,260-264


Martin PK, Marchiando A, Xu R, Rudensky E, Yeung F, Schuster SL, Kernbauer E, Cadwell K. Autophagy proteins suppress protective type I interferon signaling in response to the gut microbiota. , Nat Microbiol, 3(10): 2018,1131-1141


Ramanan D, Bowcutt R, Lee SC, Tang MS, Kurtz ZD, Ding Y, Honda K, Gause WC, Blaser MJ, Bonneau RA, Lim YA, Loke P*, Cadwell K*. Helminth Infection Promotes Colonization Resistance via Type 2 Immunity , Science, 352(6285): 2016,608-12


Kernbauer E, Ding Y, Cadwell K. An enteric virus can replace the beneficial function of commensal bacteria , Nature, 516 (7529): 2014,94-8


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