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Keith W. Hamilton, MD

Keith W. Hamilton, MD Physician

Director of Antimicrobial Stewardship Director of Infectious Diseases Transition Service Director of Internal Medicine Clerkship Assistant Professor of Clinical Medicine

Dr. Hamilton is employed by Penn Medicine.

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Clinical Specialties


  • Infectious Diseases

Programs & Centers:

Board Certification:

  • Infectious Disease, 2011
  • Internal Medicine, 2009

Clinical Expertise:

  • Bone Infection (Osteomyelitis)
  • Epidemiology
  • Multi-drug Resistant Organisms (MDROs)
  • Mycobacterial Infections
  • Soft Tissue Infection

Description of Clinical Expertise

Treatment of Non-tuberculous mycobacterial infections
Infection Control
Healthcare Epidemiology
Antimicrobial Stewardship
General Infectious Diseases

Practice Locations and Appointments

  • Penn Infectious Diseases

    Perelman Center for Advanced Medicine South Pavilion, 4th Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-7366 (PENN)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American College of Physicians, National Clerkship Directors in Internal Medicine, National Philadelphia Community Antimicrobial Stewardship Collaborative, Local Society for Healthcare Epidemiology of America, National

Hospital Affiliation

Dr. Hamilton is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Infection Control
Healthcare Epidemiology
Antimicrobial Stewardship
Non-tuberculous mycobacterial infections

Selected Publications:

Lukaszewicz Buschen J, Mehta J, Hamilton K, Binkley S, Timko D, Morgan SC, Lautenbach E, Pegues D.: Impact of two different antimicrobial stewardship methods on frequency of streamlining antimicrobial agents in patients with bacteremia. Infect Control Hosp Epidemiol [accepted] : 2016.

Szymczak JE, Gerber JS, Hamilton K.: Barriers and facilitators to implementing antimicrobial stewardship in Philadelphia-area hospitals. Society of Healthcare Epidemiology of America, Annual Conference; Atlanta, GA : 2016.

Vinnard C, Longworth S, Patrawalla A, Dartois V, Kreiswirth B, Hamilton K.: Deaths related to nontuberculous mycobacterial infections in the United States, 1999-2014. Ann Am Thorac Soc [accepted] : 2016.

Jou J, Ebrahim J, Shofer FS, Hamilton KW, Stern J, Han JH and CDC Epicenters Prevention Program: Environmental transmission of Clostridium difficile: association between hospital room size and C. difficile infection Infect Control Hosp Epidemiol 36 (5): 564-8,2015.

Sears J, Hamilton KW, Gerber JS, Szymczak J, Patel A: Assessment of local antimicrobial stewardship activities: a call for collaboration Society for Healthcare Epidemiology of America (SHEA) Spring 2015: Science Guiding Prevention Annual Conference, Orlando, FL : 2015.

Hamilton KW, Gerber JS, Moehring R, Anderson DJ, Calderwood MS, Han JH, Mehta JM, Polalck LA, Zaoutis T, Srinivasan A, Camins BC, Schwartz DN, Lautenbach E: Point-of-prescription interventions to improve antimicrobial Stewardship Clin Infect Dis 60 (8): 1252125-8,2015.

Bartsch SM, Umscheid C, Nachamkin I, Hamilton KW, Lee BY: Comparing the economic and health benefits of different approaches to diagnosing Clostridium difficile infection Clin Microbiol Infect 21 (1): e1-9,2015.

Byrne DD, Rosenbach MA, Hamilton KW: Take one's breath away Infections in the immunocompromised patient : 2015.

White D, Hamilton K, Pegues D, Hanish A, Resnic J, Umscheid C: The impact of a computerized clinical decision support tool on inappropriate Clostridium difficile testing Hospital Medicine, National Harbor, MD : 2015.

Hamilton KW, O'Donnell JA: Urinary tract infection Clinical Infectious Diseases, 2nd Edition : 2015.

Academic Contact Info

Healthcare Epidemiology, Infection Prevention and Control, Ground Founders
Hospital of the University of Pennsylvania

Philadelphia, PA 19104
Phone: 215-662-6995
Patient appointments: 800-789-7366 (PENN)