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Karthik Rajasekaran, MD, FACS

Karthik Rajasekaran, MD, FACS Physician

Director of Facial Trauma Director of Quality Improvement Education Head and Neck Oncologic & Reconstructive Surgeon Assistant Professor of Otorhinolaryngology: Head and Neck Surgery at the Hospital of the University of Pennsylvania

Languages spoken:

  • English
  • Tamil

Dr. Rajasekaran is employed by Penn Medicine.

About Dr. Karthik Rajasekaran

Dr. Karthik Rajasekaran is a head & neck oncologic and reconstructive surgeon.  He specializes in treating benign and malignant tumors of the nose, sinuses, oral cavity, oropharynx, larynx, thyroid, skin and salivary glands.  Seeking to ensure the best possible care, Dr. Raj’s particular expertise is working with patients on individualized treatment plans.

Dr. Raj’s surgery skills encompass endoscopic, minimally invasive and traditional techniques.  He also has special expertise in transoral robotic surgery (TORS), endoscopic approaches for skull base and nasal tumors, sentinel lymph node biopsy (a procedure to check whether cancer has spread), and state of the art reconstructive options following cancer surgery, injury from radiation therapy and trauma.  He is committed to treating his patients as he would his own family and prides himself on being as accessible as possible to his patients.

Dr. Raj’s research interests include outcomes for patients treated with advanced head and neck cancer, decreasing opioid use in head and neck cancer patients, and investigating methods to optimize perioperative care.  Dr. Raj has published numerous scientific publications and textbook chapters.  His research has won several national awards and he also has been awarded several research grants.  His most valuable asset is that he focuses on providing care in a patient centric and compassionate manner that meets the goals and values of his patients and their caregivers.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Otorhinolaryngology
  • Otorhinolaryngology

Programs & Centers:

Board Certification:

  • Otolaryngology, 2017

Clinical Expertise:

  • Adenocarcinoma of the Head and Neck
  • Airway Disorders
  • Alaryngeal Communication
  • Allergic Fungal Sinusitis
  • Allergic Rhinitis
  • Allergic Rhinosinusitis
  • Allergies
  • Anterior Nasal Drip
  • Arytenoid Dislocation
  • Aspirin Exacerbated Respiratory Disease
  • Balloon Sinuplasty
  • Blepharoptosis
  • Broken Nose (Nose Fracture)
  • Brow Droop
  • Brow Lift
  • Buccal Space Mass
  • Burn Reconstruction
  • Cancer of the Nasal Cavity
  • Cerebrospinal Fluid Leak from Nose
  • Cheek Problems
  • Choking Sensation
  • Chronic Rhinosinusitis
  • Chronic Sinus Infection
  • Chronic Tonsillitis
  • Cleft Lip Surgery
  • Cleidocranial Dysostosis
  • Coarse Facial Features
  • Coblation for Tonsillectomy
  • Collagen Injection
  • Cosmetic Facial Surgery
  • Cosmetic Jaw Surgery
  • Cough
  • Craniosynostosis
  • Cricopharyngeal Achalasia
  • Cross Face Nerve Graft
  • CSF Leak Repair
  • Cyst of Sinuses
  • Da Vinci Head & Neck Surgery
  • Dacryocystorhinostomy
  • Dermal Fillers
  • Deviated Septum
  • Difficulty Speaking
  • Difficulty Swallowing (Dysphagia)
  • Digastric Muscle Transfer
  • Disorder of Ear Lobe
  • Dizziness
  • Double Chin
  • Dry Mouth (Xerostomia)
  • Dysphonia
  • Ear and Temporal Bone Tumors
  • Ear Exam
  • Ear Fullness
  • Ear Mass
  • Ear, Nose and Throat Surgery
  • Ectodermal Dysplasias
  • Endoscopic Dacryocystorhinostomy
  • Esophageal Dilation
  • Esophageal Obstruction
  • Ethmoidectomy
  • Eyelid Repair
  • Eyelid Surgery (Blepharoplasty)
  • Face Lift Surgery (Rhytidectomy)
  • Face Swelling
  • Facial Abscess
  • Facial Asymmetry
  • Facial Asymmetry Surgery
  • Facial Deformities
  • Facial Fracture
  • Facial Implants
  • Facial Lesion
  • Facial Nerve Disorders
  • Facial Nerve Graft
  • Facial Nerve Injury
  • Facial Nerve Palsy
  • Facial Nerve Schwannoma
  • Facial Pain
  • Facial Paralysis Reconstruction
  • Facial Paresis
  • Facial Reconstruction
  • Facial Rehabilitation
  • Facial Vein
  • Fine Needle Aspiration
  • Fissured Tongue
  • forehead lift
  • Forehead Nodule
  • Frenectomy
  • Frontalis Muscle Transfer
  • Gastroesophageal Reflux Disease (GERD)
  • Glottic Stenosis
  • Goiter
  • Gold Eyelid Weight
  • Head and Neck Tumor Reconstruction
  • Head Mass
  • History of Pituitary Mass
  • Hoarseness
  • Hypercalcemia
  • Hyperparathyroidism
  • Hypertelorism
  • Hypoglossal Nerve Disease
  • Hypoglossal Nerve Injury
  • Hypoglossal Nerve Stimulator
  • Hypoglossal Nerve Transfers
  • Injection Medialization Laryngoplasty
  • Interposition Nerve Grafts
  • Inverted Papilloma
  • Jaw Bone Graft
  • Jaw Disorders
  • Jaw Reconstruction
  • Keloid Scar
  • Laryngeal Dysphagia
  • Laryngeal Dysplasia
  • Laryngeal Dystonia
  • Laryngeal Edema
  • Laryngeal Lesion
  • Laryngeal Leukoplakia
  • Laryngeal Papillomatosis
  • Laryngeal Polyps
  • Laryngeal Stenosis
  • Laryngectomy
  • Laryngitis
  • Laryngoscopy
  • Laryngotracheoplasty
  • Laser-Assisted Uvulopalatoplasty
  • Lefort Fracture
  • Lip Asymmetry
  • Lip Droop
  • Lip Surgery
  • Local Muscle Transfers
  • Ludwig's Angina
  • Lump in Throat
  • Mandibulectomy
  • Masseter-to-Facial Nerve Transfer
  • Maxillectomy
  • Maxillomandibular Advancement
  • Melanoma on Face
  • Micrognathia
  • Microsurgery
  • Microvascular Flap Reconstruction
  • Middle Ear Exploration
  • Mid-Face Lift
  • Midfacial Hypoplasia
  • Mouth Abscess
  • Mouth Bleeding
  • Nasal Cancer
  • Nasal Cavity and Paranasal Sinus Cancer
  • Nasal Crusting
  • Nasal Drainage
  • Nasal Endoscopy
  • Nasal Obstruction
  • Nasal Polyps
  • Nasal Trauma
  • Nasoseptal Reconstruction
  • Neck Abscess
  • Neck Biopsy
  • Neck Cyst
  • Neck Lift
  • Neck Lymph Nodes
  • Neck Mass Excision
  • Neck Masses and Lumps
  • Neck Plastic Surgery
  • Neck Reconstruction
  • Neurofibromatosis
  • Neurologic Disorders of the Larynx
  • Nose Bleed
  • Nose Deformities
  • Nose Surgery (Rhinoplasty)
  • Obstructive Sleep Apnea
  • Odynophagia
  • Olfactory Nerve Disease
  • Oral Inflammation
  • Oral Lesions
  • Oral Pathology
  • Oropharyngeal Disorders
  • Osteoma
  • Otalgia
  • Paranasal Surgery
  • Parapharyngeal Abscess
  • Parapharyngeal Mass
  • Parathyroidectomy
  • Peroral Endoscopic Myotomy
  • Pharyngeal Flap Surgery
  • Pharyngeal Mass
  • Polyp of Cheek
  • Positional Vertigo
  • Post-Nasal Drip
  • Preauricular Fistula
  • Problems with Smell and Taste
  • Rasping of the Nasal Dorsum
  • Reconstruction of Ear
  • Reconstruction of Nose
  • Reconstructive Plastic Surgery
  • Retropharyngeal Abscess
  • Rhinitis
  • Rhinorrhea
  • Rib Cartilage Rhinoplasty
  • Salivary Duct
  • Salivary Gland Disorders
  • Salivary Gland Swelling
  • Scalp Transplant
  • Scar on Neck
  • Scratchy Voice
  • Septal Perforation
  • Septoplasty
  • Sialadenitis
  • Sialolithiasis
  • Sinonasal Carcinoma
  • Sinonasal Mucocele
  • Sinonasal Papilloma
  • Sinus and Nasal Mucoceles
  • Sinus Disorders
  • Sinus Infections (Sinusitis)
  • Sinus Mass
  • Sinus Polyp
  • Sinus Pressure
  • Sinus Surgery
  • Skin Fillers
  • Skin Resurfacing and Rejuvenation
  • Sleep Apnea
  • Sleep Disorders
  • Sleep Endoscopy
  • Sleep-Related Hypoventilation
  • Small Ear Canal
  • Smell Disorders
  • Smile Restoration
  • Snoring
  • Speech Aid Prosthesis
  • Sphenoidectomy
  • Sphenoidotomy
  • Spots on Mouth
  • Squamous Cell Carcinoma of the Skin of Lip
  • Stomatitis
  • Stylohyoid Syndrome
  • Subglottic Stenosis
  • Submandibular Nodule
  • Submandibular Swelling
  • Swallowing Disorders
  • Swollen Lymph Nodes
  • Swollen Parotid
  • Swollen Throat
  • Swooshing Sound in Ears
  • Temporal Bone Fracture
  • Temporalis Muscle Transfers
  • Throat Abscess
  • Throat Disorders
  • Throat Drainage
  • Throat Mass
  • Thyroglossal Duct Disorders
  • Thyroid Nodules
  • Thyroidectomy
  • Tongue Mass
  • Tongue Pain
  • Tongue Swelling
  • Tonsil Removal Surgery (Tonsillectomy)
  • Tonsillar Abscess
  • Tonsillar Hypertrophy
  • Tracheal Dilatation
  • Tracheal Stomal Stenosis
  • Tracheocutaneous Fistula
  • Tracheostomy Management
  • Transnasal Repair CSF Leak
  • Transoral Robotic Surgery for Obstructive Sleep Apnea
  • Uprastomal and Tracheal Granulomas
  • Uvuloplasty
  • Velopharyngeal Insufficiency
  • Vermilionectomy
  • Videostroboscopy
  • Vocal Cord Dysfunction
  • Vocal Cord Issues
  • Vocal Cord Lesion
  • Vocal Cord Paralysis
  • Vocal Cord Strain
  • Vocal Cord Surgery
  • Voice Disorders
  • Voice Prosthesis
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Rosalind Franklin University
Residency: Cleveland Clinic Foundation
Fellowship: Hospital of the University of Pennsylvania


Alpha Omega Alpha Honor Medical Society, National American Academy of Otolaryngology – Head and Neck Surgery, National American College of Surgeons, National American Head and Neck Society, National American Medical Association, National Gold Humanism Honor Society, National Northeast Ohio Otolaryngology-Head and Neck Society, Local

Hospital Affiliation

Dr. Rajasekaran is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Rajasekaran K, Stubbs V, Chen J, Yalamanchi P, Cannady S, Brant J, Newman J: Mucoepidermoid Carcinoma of the Parotid Gland: A National Cancer Data Base Study Combined Otolaryngology Sections Meeting (COSM), Baltimore, MD : 2018.

Rajasekaran K, Yarpak N, Adelberg J, O'Malley B, Newman J, Cannady S, Chalian A, Rassekh C, Lin A, Lukens J, McClure S, Cohen R, Aggarwal C, Bauml J, Weinstein G: Transoral Robotic Surgery-Assisted Endoscopy with Primary Site Detection for Occult Mucosal Primaries- 2 Year Survival Combined Otolaryngology Sections Meeting, Baltimore, MD : 2018.

Yalamanchi P, Workman A, Thomas W, Rajasekaran K, Chalian A, Shanti R, Newman J, Cannady S: An Evaluation of Clinical Outcomes and Cost Free Osteocutaneous Fibula Flap for Reconstruction of Head and Neck Surgical Defects Combined Otolaryngology Sections Meeting (COSM), Baltimore, MD : 2018.

Rajasekaran K, Stubbs V, Chen J, Yalamanchi P, Cannady S, Brant J, Newman J: Mucoepidermoid Carcinoma of the Parotid Gland: A National Cancer Database Study Am J Otolaryngol S0196-0709 (18): 30043-7,2018.

Ranasinghe V, Lerner D, Rajasekaran K, Shanti R, Newman J, Cannady S: Uvular Metastisis of Renal Cell Carcinoma 27 years after Nephrectomy Triological Society Combined Sections Meeting, Scottsdale, AZ : 2018.

19., Stubbs V, Rajasekaran K, Gigliotti A, Mahmoud A, Brody R, Newman J, Rassekh C, Weinstein G.: Management of the Airway for Transoral Robotic Supraglottic Partial Laryngectomy Frontiers in Oncology 8 : 312,2018.

Gomez D, Thakkar P, Rajasekaran K, Brody R, Shanti R, Newman J, Cannady S: Patient Characteristics as Predictors of Postoperative Complications in Free Flap Reconstruction for Head and Neck Cancer Combined Otolaryngologic Spring Meeting, San Diego, CA : 2017.

Chao T, Mahmoud A, Rajasekaran K, Mirza N: Medialization Thyroplasty with Tensor Fascia Lata. A Novel Approach for Reducing Post-Thyroplasty Complications Combined Otolaryngologic Spring Meeting, San Diego, CA : 2017.

Rajasekaran K, Fritz M: Making Small from Big-Combining Rotation/Advancement and Composite Grafts for Management of Complex Nasal Defects Combined Otolaryngologic Spring Meeting, Chicago, IL : 2016.

Rajasekaran K, Fritz M: Reconstruction of Central Palate Sparing Bilateral Lateral Maxillectomy Defect with Split Perforator Anterolateral Thigh Flap using a Minimal Access Approach Combined Otoalaryngologic Spring Meeting, Chicago, IL : 2016.

Academic Contact Info

800 Walnut St, 18th Floor
Department of Otorhinolaryngology
Penn Medicine

Philadelphia, PA 19107
Phone: (215) 829-5180
Patient appointments: 800-789-7366 (PENN)