Adults (18-65), Geriatrics (65+)
Adults (18-65), Geriatrics (65+)
Internal Medicine, 2010
Medical Oncology, 2014
Abramson Cancer Center
Perelman Center for Advanced Medicine, West Pavilion, 3rd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
A facility of the Hospital of the University of Pennsylvania
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I am a Medical Oncologist with postdoctoral training in Cancer Genetics and PhD training in molecular and cellular biology. My research interests are in the genetics of human disease, particularly familial cancers, and in the translation of genetic data for managing individuals at risk for cancer. My laboratory is using human genetic and genomic data coupled with model systems to study mechanisms of cancer formation in patients with inherited forms of breast and prostate cancer.
Ding J, Feld E, Le A, Sanchez P, Powers J, Doucette A, McLaughlin M, Judy R, Kember R, Weaver J, Gabriel P, Damrauer SM, Rader DJ, Domchek SM, Lee DJ, Narayan V, Schwartz LE, Maxwell KN: Burden of genetic testing in an academic biobank by pathological and family history-based criteria in prostate cancer American Society of Clinical Oncology Annual Meeting 2020 Submitted Abstract Temporary ID #: 295099 : 2020.
Desai H, Le A, Hausler R, Verma SS, Verma A, Judy R, Doucette A, Regeneron Genetics Center, Gabriel P, Damrauer SM, Ritchie MD, Rader DJ, Kember RL, Maxwell KN: Performance of polygenic risk scores for cancer prediction in an academic biobank American Society of Clinical Oncology Annual Meeting 2020 Submitted Abstract, Temporary ID#: 301931 : 2020.
Le AN, Powers J, Zelley K, Bradbury AR, Shah P, Freedman G, Nathanson KL, Domchek SM, MacFarland SP, Maxwell KN: Frequency of radiation-induced malignancies post-adjuvant radiotherapy for breast cancer in patients with Li-Fraumeni syndrome San Antonio Breast Cancer Symposium Annual Meeting 2019 Abstract P4-12-33 : 2019.
Feld E, Le A, Ding J, Desai H, Kelly G, Parikh R, Narayan V, Doucette A, Regeneron Genetics Center, Gabriel P, Kember R, Damrauer SM, Rader DJ, Lee D, Schwartz L, Maxwell KN: Implication of Gleason score for the precision medicine treatment of
patients with localized prostate cancer Prostate Cancer Foundation Annual Meeting 2019 : 2019.
Clark DF, Maxwell KN, Powers J, Lieberman DB, Ebrahimzadeh J, Long JM, McKenna D, Shah P, Bradbury A, Morrissette JJD, Nathanson KL, Domchek SM: Identification and Confirmation of Potentially
Actionable Germline Mutations in Tumor-Only
Genomic Sequencing JCO Precision Oncology epub : 2019.
Gaieski JB, Patrick-Miller L, Egleston BL, Maxwell KN, Walser S, DiGiovanni L, Brower J, Fetzer D, Ganzak A, McKenna D, Long JM, Powers J, Stopfer JE, Nathanson KL, Domchek SM, Bradbury AR: Research participants' experiences with return of genetic research results and preferences for web-based alternatives. Mol Genet Genomic Med epub : 2019.
Kraya AA, Maxwell KN, Wubbenhorst B, Wenz BM, Pluta J, Rech AJ, Dorfman LM, Lunceford N, Barrett A, Mitra N, Morrissette JJ, Feldman M, Nayak A, Domchek SM, Vonderheide RH, Nathanson KL: Genomic signatures predict the immunogenicity of BRCA-deficient breast cancer. Clinical Cancer Research Epub ahead of print : 2019.
MacFarland SP, Zelley K, Long JM, McKenna D, Mamula P, Domchek SM, Nathanson KL, Brodeur GM, Rustgi AK, Katona BW, Maxwell KN: Earlier colorectal cancer screening may be necessary in patients with Li-Fraumeni Syndrome. Gastroenterology 5085 (18): 35028-5,2018.
MacFarland SP, Maxwell KN: The differential diagnosis of a TP53 genetic testing result Genetics in Medicine epub ahead of print : 2018.
Breitenstein MK, Liu H, Maxwell KN, Pathak J, Zhang R: Electronic health record phenotypes for precision medicine: perspectives and caveats from treatment of breast cancer at a single institution Clinical and Translational Science 11 (1): 85-92,2018.
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