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Kara N. Maxwell, MD, PHD

Kara N. Maxwell, MD, PHD Physician

Assistant Professor of Medicine Assistant Professor of Genetics

Dr. Maxwell is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Hematology
  • Medical Oncology

Programs & Centers:

Board Certification:

  • Internal Medicine, 2010
  • Medical Oncology, 2014

Clinical Expertise:

  • Breast Cancer Genetics
  • Cancer Genetic Testing
  • Cancer Risk Evaluation

Description of Clinical Expertise

cancer risk evaluation, breast cancer, hereditary breast ovarian cancer, Li Fraumeni Syndrome, Fanconi Anemia

Practice Locations and Appointments

  • Rena Rowan Breast Center

    Abramson Cancer Center Perelman Center for Advanced Medicine, West Pavilion, 3rd Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-7366 (PENN)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Weill Medical College of Cornell University
Residency: NewYork-Presbyterian/Columbia University Medical Center
Fellowship: Hospital of the University of Pennsylvania


American Association of Cancer Research, National American Society of Clinical Oncology, National American Society of Human Genetics, National Facing Our Risk of Cancer Empowered (FORCE), National

Hospital Affiliation

Dr. Maxwell is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

I am a Medical Oncologist and PhD trained molecular and cellular biologist. My research interests are in the genetics of human disease, particularly familial cancers, and in the translation of genetic data for managing individuals at risk for cancer and for directing novel therapies for oncology patients.

Selected Publications:

MacFarland SP, Zelley K, Long JM, McKenna D, Mamula P, Domchek SM, Nathanson KL, Brodeur GM, Rustgi AK, Katona BW, Maxwell KN: Earlier colorectal cancer screening may be necessary in patients with Li-Fraumeni Syndrome. Gastroenterology 5085 (18): 35028-5,2018.

MacFarland SP, Maxwell KN: The differential diagnosis of a TP53 genetic testing result Genetics in Medicine epub ahead of print : 2018.

Breitenstein MK, Liu H, Maxwell KN, Pathak J, Zhang R: Electronic health record phenotypes for precision medicine: perspectives and caveats from treatment of breast cancer at a single institution Clinical and Translational Science 11 (1): 85-92,2018.

Maxwell KN, Wubbenhorst B, Wenz BM, De Sloover D, Pluta J, Emery L, Barrett A, Kraya AA, Anastopoulos IN, Yu S, Jiang Y, Chen H, Zhang NR, Hackman N, D'Andrea K, Daber R, Morrissette JJD, Mitra N, Feldman M, Domchek SM, Nathanson KL.: BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers Nature Communications 8 (1): 319,2017.

Nian X, Nagai Y, Jeffers C, Maxwell KN, Zhang H: Dietary influence on estrogens and cytokines in breast cancer AIMS Molecular Science 4 (3): 252-270,2017.

Slavin TP*, Maxwell KN*, Lilyquist J*, Vijai J*, Neuhausen SL, Hart SN, Ravichandran V, Thomas T, Maria A, Villano D, Schrader KA, Moore R, Hu C, Wubbenhorst B, Wenz BM, D'Andrea K, Robson ME, Peterlongo P, Bonanni B, Ford JM, Garber JE, Domchek SM, Szabo C, Offit K, Nathanson KL, Weitzel JN, Couch FJ (*shared first authorship): The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk NPJ Breast Cancer 3 : 22,2017.

Chen H, Jiang Y, Maxwell KN, Nathanson KL, Zhang N.: Allele-specific copy number estimation by whole exome sequencing Ann Appl Stat 11 (2): 1169-1192,2017.

Maxwell KN, Soucier-Ernst D, Tahirovic E, Troxel AB, Clark C, Feldman M, Colameco C, Kakrecha B, Langer M, Lieberman D, Morrissette JJD, Paul MR, Pan TC, Yee S, Shih N, Carpenter E, Chodosh LA, DeMichele A: Comparative clinical utility of tumor genomic testing and cell-free DNA in metastatic breast cancer. Breast Cancer Research and Treatment 164 (3): 627-638,2017.

Maxwell KN, Domchek SM, Nathanson KL, Robson ME: Population Frequency of Germline BRCA1/2 Mutations. Journal of Clinical Oncology 34 (34): 4183-4185,2016.

Vijai J, Topka S, Villano D, Ravichandran V, Maxwell KN, Maria A, Thomas T, Gaddam P, Lincoln A, Kazzaz S, Wenz B, Carmi S, Schrader KA, Hart SN, Lipkin SM, Neuhausen SL, Walsh MF, Zhang L, Lejbkowicz F, Rennert H, Stadler ZK, Robson M, Weitzel JN, Domchek S, Daly MJ, Couch FJ, Nathanson KL, Norton L, Rennert G, Offit K: A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer. Cancer Discovery 6 (11): 1267-1275,2016.

View all publications

Academic Contact Info

BRB Room 810
421 Curie Blvd

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)