Adults (18-65), Geriatrics (65+)
Adults (18-65), Geriatrics (65+)
Internal Medicine, 2010
Medical Oncology, 2014
Abramson Cancer Center
Perelman Center for Advanced Medicine, West Pavilion, 3rd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
A facility of the Hospital of the University of Pennsylvania
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I am a Medical Oncologist with postdoctoral training in Cancer Genetics and PhD training in molecular and cellular biology. My research interests are in the genetics of human disease, particularly familial cancers, and in the translation of genetic data for managing individuals at risk for cancer. My laboratory is using human genetic and genomic data coupled with model systems to study mechanisms of cancer formation in patients with inherited forms of breast and prostate cancer.
Clark DF, Maxwell KN, Powers J, Lieberman DB, Ebrahimzadeh J, Long JM, McKenna D, Shah P, Bradbury A, Morrissette JJD, Nathanson KL, Domchek SM: Identification and Confirmation of Potentially
Actionable Germline Mutations in Tumor-Only
Genomic Sequencing JCO Precision Oncology epub : 2019.
Gaieski JB, Patrick-Miller L, Egleston BL, Maxwell KN, Walser S, DiGiovanni L, Brower J, Fetzer D, Ganzak A, McKenna D, Long JM, Powers J, Stopfer JE, Nathanson KL, Domchek SM, Bradbury AR: Research participants' experiences with return of genetic research results and preferences for web-based alternatives. Mol Genet Genomic Med epub : 2019.
Kraya AA, Maxwell KN, Wubbenhorst B, Wenz BM, Pluta J, Rech AJ, Dorfman LM, Lunceford N, Barrett A, Mitra N, Morrissette JJ, Feldman M, Nayak A, Domchek SM, Vonderheide RH, Nathanson KL: Genomic signatures predict the immunogenicity of BRCA-deficient breast cancer. Clinical Cancer Research Epub ahead of print : 2019.
MacFarland SP, Zelley K, Long JM, McKenna D, Mamula P, Domchek SM, Nathanson KL, Brodeur GM, Rustgi AK, Katona BW, Maxwell KN: Earlier colorectal cancer screening may be necessary in patients with Li-Fraumeni Syndrome. Gastroenterology 5085 (18): 35028-5,2018.
MacFarland SP, Maxwell KN: The differential diagnosis of a TP53 genetic testing result Genetics in Medicine epub ahead of print : 2018.
Breitenstein MK, Liu H, Maxwell KN, Pathak J, Zhang R: Electronic health record phenotypes for precision medicine: perspectives and caveats from treatment of breast cancer at a single institution Clinical and Translational Science 11 (1): 85-92,2018.
Maxwell KN, Wubbenhorst B, Wenz BM, De Sloover D, Pluta J, Emery L, Barrett A, Kraya AA, Anastopoulos IN, Yu S, Jiang Y, Chen H, Zhang NR, Hackman N, D'Andrea K, Daber R, Morrissette JJD, Mitra N, Feldman M, Domchek SM, Nathanson KL.: BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers Nature Communications 8 (1): 319,2017.
Nian X, Nagai Y, Jeffers C, Maxwell KN, Zhang H: Dietary influence on estrogens and cytokines in breast cancer AIMS Molecular Science 4 (3): 252-270,2017.
Chen H, Jiang Y, Maxwell KN, Nathanson KL, Zhang N.: Allele-specific copy number estimation by whole exome sequencing Ann Appl Stat 11 (2): 1169-1192,2017.
Slavin TP*, Maxwell KN*, Lilyquist J*, Vijai J*, Neuhausen SL, Hart SN, Ravichandran V, Thomas T, Maria A, Villano D, Schrader KA, Moore R, Hu C, Wubbenhorst B, Wenz BM, D'Andrea K, Robson ME, Peterlongo P, Bonanni B, Ford JM, Garber JE, Domchek SM, Szabo C, Offit K, Nathanson KL, Weitzel JN, Couch FJ (*shared first authorship): The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk NPJ Breast Cancer 3 : 22,2017.
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