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Kara N. Maxwell, MD, PHD

Kara N. Maxwell, MD, PHD Physician

Assistant Professor of Medicine Assistant Professor of Genetics

Dr. Maxwell is employed by Penn Medicine.

Clinical Specialties

Specialty:

  • Hematology
  • Medical Oncology

Programs & Centers:

Board Certification:

  • Internal Medicine, 2010
  • Medical Oncology, 2014

Clinical Expertise:

  • Breast Cancer Genetics
  • Cancer Genetic Testing
  • Cancer Risk Evaluation

Practice Locations and Appointments

  • Rena Rowan Breast Center

    Abramson Cancer Center Perelman Center for Advanced Medicine, West Pavilion, 3rd Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-7366 (PENN)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Weill Medical College of Cornell University
Residency: NewYork-Presbyterian/Columbia University Medical Center
Fellowship: Hospital of the University of Pennsylvania

Memberships

American Association of Cancer Research, National American Society of Clinical Oncology, National American Society of Human Genetics, National Facing Our Risk of Cancer Empowered (FORCE), National

Hospital Affiliation

Dr. Maxwell is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

I am a Medical Oncologist with postdoctoral training in Cancer Genetics and PhD training in molecular and cellular biology. My research interests are in the genetics of human disease, particularly familial cancers, and in the translation of genetic data for managing individuals at risk for cancer. My laboratory is using human genetic and genomic data coupled with model systems to study mechanisms of cancer formation in patients with inherited forms of breast and prostate cancer.

Selected Publications:

Kraya AA, Maxwell KN, Wubbenhorst B, Wenz BM, Pluta J, Rech AJ, Dorfman LM, Lunceford N, Barrett A, Mitra N, Morrissette JJ, Feldman M, Nayak A, Domchek SM, Vonderheide RH, Nathanson KL: Genomic signatures predict the immunogenicity of BRCA-deficient breast cancer. Clinical Cancer Research Epub ahead of print : 2019.

MacFarland SP, Zelley K, Long JM, McKenna D, Mamula P, Domchek SM, Nathanson KL, Brodeur GM, Rustgi AK, Katona BW, Maxwell KN: Earlier colorectal cancer screening may be necessary in patients with Li-Fraumeni Syndrome. Gastroenterology 5085 (18): 35028-5,2018.

MacFarland SP, Maxwell KN: The differential diagnosis of a TP53 genetic testing result Genetics in Medicine epub ahead of print : 2018.

Breitenstein MK, Liu H, Maxwell KN, Pathak J, Zhang R: Electronic health record phenotypes for precision medicine: perspectives and caveats from treatment of breast cancer at a single institution Clinical and Translational Science 11 (1): 85-92,2018.

Maxwell KN, Wubbenhorst B, Wenz BM, De Sloover D, Pluta J, Emery L, Barrett A, Kraya AA, Anastopoulos IN, Yu S, Jiang Y, Chen H, Zhang NR, Hackman N, D'Andrea K, Daber R, Morrissette JJD, Mitra N, Feldman M, Domchek SM, Nathanson KL.: BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers Nature Communications 8 (1): 319,2017.

Nian X, Nagai Y, Jeffers C, Maxwell KN, Zhang H: Dietary influence on estrogens and cytokines in breast cancer AIMS Molecular Science 4 (3): 252-270,2017.

Chen H, Jiang Y, Maxwell KN, Nathanson KL, Zhang N.: Allele-specific copy number estimation by whole exome sequencing Ann Appl Stat 11 (2): 1169-1192,2017.

Slavin TP*, Maxwell KN*, Lilyquist J*, Vijai J*, Neuhausen SL, Hart SN, Ravichandran V, Thomas T, Maria A, Villano D, Schrader KA, Moore R, Hu C, Wubbenhorst B, Wenz BM, D'Andrea K, Robson ME, Peterlongo P, Bonanni B, Ford JM, Garber JE, Domchek SM, Szabo C, Offit K, Nathanson KL, Weitzel JN, Couch FJ (*shared first authorship): The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk NPJ Breast Cancer 3 : 22,2017.

Maxwell KN, Soucier-Ernst D, Tahirovic E, Troxel AB, Clark C, Feldman M, Colameco C, Kakrecha B, Langer M, Lieberman D, Morrissette JJD, Paul MR, Pan TC, Yee S, Shih N, Carpenter E, Chodosh LA, DeMichele A: Comparative clinical utility of tumor genomic testing and cell-free DNA in metastatic breast cancer. Breast Cancer Research and Treatment 164 (3): 627-638,2017.

Maxwell KN, Domchek SM, Nathanson KL, Robson ME: Population Frequency of Germline BRCA1/2 Mutations. Journal of Clinical Oncology 34 (34): 4183-4185,2016.

View all publications

Academic Contact Info

BRB Room 810
421 Curie Blvd

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)