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Kai Ruppert, PhD

Kai Ruppert, PhD Researcher

Research Assistant Professor of Radiology

Dr. Ruppert is employed by Penn Medicine.

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International Society for Magnetic Resonance in Medicine (ISMRM), International

Hospital Affiliation

Dr. Ruppert is employed by Penn Medicine.


Selected Publications:

Thomen RP, Quirk JD, Roach D, Egan-Rojas T, Ruppert K, Patterson GA, Altes TA, Yablonskiy D, , Woods JC.: Direct comparison of 129 Xe diffusion measurements with quantitative histology in human lungs. Magn Reson Med 77 (1): 265-272,2017.

Ruppert K, Altes TA, Mata JF, Ruset IC, Hersman FW, Mugler JP 3rd.: Detecting Pulmonary Capillary Blood Pulsations Using Hyperpolarized 129Xe Chemical Shift Saturation Recovery (CSSR) MR Spectroscopy. Magn Reson Med 75 (4): 1771-80,2016.

Qing K, Mugler JP 3rd, Altes TA, Jiang Y, Mata JF, Miller GW, Ruset IC, Hersman FW, Ruppert K.: Assessment of Lung Function in Asthma and COPD using Hyperpolarized 129Xe Chemical Shift Saturation Recovery Spectroscopy and Dissolved-Phase MR Imaging. NMR in Biomedicine 27 (12): 1490-1501,2014.

Ruppert K.: Biomedical imaging with hyperpolarized noble gases. Rep. Prog. Phys. 77 (11): 116701,2014.

Mata J, Sheng K, Hagspiel K, Ruppert K, Sylvester P, Mugler J 3rd, Fernandes C, Guan S, Larner J, Read, P.: Pulmonary toxicity in a rabbit model of stereotactic lung radiation therapy: Efficacy of a radio protector. Exp Lung Res. 40 (6): 308-16,2014.

Qing K, Ruppert K, Jiang Y, Mata JF, Miller GW, Shim YM, Wang C, Ruset IC, Hersman FW, Altes TA, Mugler JP 3rd.: Regional mapping of gas uptake by blood and tissue in the human lung using hyperpolarized xenon-129 MRI. J Magn Reson Imaging. 39 (2): 346-59,2014.

Dregely IM, Ruset IC, Wiggins G, Mareyam A, Altes TA, Mugler III JP, Altes TA, Meyer C, Ruppert K, Wald LL, Hersman FW.: 32-channel phased-array receive with asymmetric birdcage transmit coil for hyperpolarized xenon-129 lung imaging. Magn Reson Med 70 (2): 576-583,2012.

Mackenzie JD, Hernandez A, Pena A, Ruppert K, Khrichenko D, Gonzalez L, Jawad AF, Wells L, Smith-, Whitley K, Jaramillo D.: Magnetic resonance imaging in children with sickle cell disease - detecting alterations in the apparent diffusion coefficient in hips with avascular necrosis. Pediatr Radiol 42 (6): 706-713,2012.

Dregely IM, Ruset IC, Mata JF, Ketel J, Ketel S, Distelbrink J, Altes TA, Mugler III JP, Miller GW, Hersman, FW, Ruppert K.: Multiple-Exchange-Time Xenon Polarization Transfer Contrast (MXTC) MRI: Initial Results in Animals and Healthy Volunteers. Magn Reson Med 67 (4): 943-953,2012.

Dregely I, Mugler JP 3rd, Ruset IC, Altes TA, Mata JF, Miller GW, Ketel J, Ketel S, Distelbrink J, Hersman FW, Ruppert K: "Hyperpolarized Xenon-129 Gas-Exchange Imaging of Lung Microstructure: First Case Studies in Subjects With Obstructive Lung Disease". J Magn Reson Imaging 33 (5): 1052-62,2011.

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Academic Contact Info

University of Pennsylvania
Department of Radiology
3400 Spruce St. 1, Silverstein

Philadelphia, PA 19104