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Julia C. Tchou, MD, PhD, FACS

Julia C. Tchou, MD, PhD, FACS Physician

Co-Director, Rena Rowan Breast Center Section Chief, of Breast Surgery Associate Professor of Clinical Surgery

Languages spoken:

  • Cantonese

Dr. Tchou is employed by Penn Medicine.

About Dr. Julia C. Tchou

Recognized by America's Top Doctors 2015 – 2018

Recognized by Best Doctors in America 2015, 2016

Recognized in Philadelphia magazine's May 2018 Top Docs issue

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Endocrine and Oncologic Surgery

Programs & Centers:

Board Certification:

  • Surgery, 2010

Clinical Expertise:

  • Benign and Malignant Breast Disease
  • Breast Cancer
  • Breast Cancer Risk Reduction
  • Breast Cancer Screening
  • Breast Conserving Surgery (Lumpectomy)
  • Breast MRI
  • Breast Surgery
  • Cancer Prevention and Early Detection
  • Clinical Trials
  • Ductal Carcinoma in Situ (DCIS)
  • Inflammatory Breast Cancer (IBC)
  • Invasive (Infiltrating) Ductal Carcinoma (IDC)
  • Invasive (Infiltrating) Lobular Carcinoma (ILC)
  • Invasive Breast Cancer
  • Male Breast Cancer
  • Molecular Breast Imaging
  • Nipple-Sparing Mastectomy (NSM)
  • Prophylactic Mastectomy
  • Sentinel Lymph Node Mapping and Biopsy
  • Skin-Sparing Mastectomy
  • Targeted Therapy
  • Triple-Negative Breast Cancer

Description of Clinical Expertise

Julia Tchou, MD PhD, FACS is Section Chief of Breast Surgery in the Division of Endocrine and Oncologic Surgery, and Co-Director of the Rena Rowan Breast Center at the Abramson Cancer Center of the Perelman School of Medicine at the University of Pennsylvania. Dr. Tchou’s practice focuses on the interdisciplinary management of patients with breast cancer: coordinating pre-operative evaluation, surgery and post-operative care of men and women with malignant breast diseases.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Vetrans Choice Program (6/2018 Not Active)

Education and Training

Medical School: State University of New York at Stony Brook
Residency: Johns Hopkins Hospital
Fellowship: Johns Hopkins Hospital
Fellowship: Northwestern Medical Center


Abramson cancer Center, Perelman School of Medicine at the University of Pennsylvania, Local American Associate of Cancer Research, National American Cancer Society Institutional Research Grant at the Wistar Institute, National American College of Surgeons, National American College of Surgeons, National American Society of Clinical Oncology, National Association of Academic Surgery, National Association of Women Surgeons, National Breast Cancer Alliance, National Breast Cancer Research Program, Department of Defense Congressionally Directed Medical Research programs, National Cancer Center at the Wistar Institute, Local Developmental Pilot Project Grant review, TREC, National DOD, CDRMP, Breast Cancer Research Program, National ECOG Breast Committee's Local-Regional Working Group, Local ECOG Breast Committee's Local-Regional Working Group, Local Global Breast Cancer Tumor Board, National NIH/NCI IMAT, National NIH/NCI Provocative Questions Initiative Grant Review panel member, National NIH/NCI UH2/UH3, National Scientist Reviewer, Department of Defense, CDRMP, Breast Cancer Research Program, National Society of Asian Academic Surgeons, National Society of Surgical Oncology, Breast Disease Site Working Group, National Society of Surgical Oncology, National The Wistar Institute Cancer Center,, Local Tumor Microenivronment and Metastasis Program, The Wistar institute, Philadelphia, PA, Local Women in Surgery Committee, American college of surgeons, National

Hospital Affiliation

Dr. Tchou is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

My research is focused on 1) developing strategies to mitigate breast cancer risk associated with metabolic syndrome by lifestyle modifications and by re-purposing some of the commonly prescribed medications to prevent breast cancer initiation and progression; 2) elucidating how novel immunotherapy such as CAR T therapy can induce epitope spreading and how combination therapy can unleash the anti-tumor effects of our own immune system; and 3) how we can use large data to enhance our understanding of tumor biology with the common goal of improving breast cancer outcomes.

Selected Publications:

Tchou Julia, Zhao Yangbing, Levine Bruce L, Zhang Paul J, Davis Megan M, Melenhorst Jan Joseph, Kulikovskaya Irina, Brennan Andrea L, Liu Xiaojun, Lacey Simon F, Posey Avery D, Williams Austin D, So Alycia, Conejo-Garcia Jose R, Plesa Gabriela, Young Regina M, McGettigan Shannon, Campbell Jean, Pierce Robert H, Matro Jennifer M, DeMichele Angela M, Clark Amy S, Cooper Laurence J, Schuchter Lynn M, Vonderheide Robert H, June Carl H: Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer. Cancer immunology research 5 (12): 1152-1161,2017.

So Alycia, De La Cruz Lucy M, Williams Austin D, Bahng Joseph, Liao Geraldine, McDonald Elizabeth S, Fisher Carla S, Czerniecki Brian J, Sataloff Dahlia, Tchou Julia: The impact of preoperative magnetic resonance imaging and lumpectomy cavity shavings on re-excision rate in pure ductal carcinoma in situ-A single institution's experience. Journal of surgical oncology : 2017.

Mustafa Rose E, DeStefano Lauren M, Bahng Joey, Yoon-Flannery Kahyun, Fisher Carla S, Zhang Paul J, Tchou Julia, Czerniecki Brian J, De La Cruz Lucy M: Evaluating the Risk of Upstaging HER2-Positive DCIS to Invasive Breast Cancer. Annals of surgical oncology 24 (10): 2999-3003,2017.

Williams Austin D, So Alycia, Synnestvedt Marie, Tewksbury Colleen M, Kontos Despina, Hsiehm Meng-Kang, Pantalone Lauren, Conant Emily F, Schnall Mitchell, Dumon Kristoffel, Williams Noel, Tchou Julia: Mammographic breast density decreases after bariatric surgery. Breast cancer research and treatment 165 (3): 565-572,2017.

Nabet Barzin Y, Qiu Yu, Shabason Jacob E, Wu Tony J, Yoon Taewon, Kim Brian C, Benci Joseph L, DeMichele Angela M, Tchou Julia, Marcotrigiano Joseph, Minn Andy J: Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer. Cell 170 (2): 352-366.e13,2017.

Cochran J M, Chung S H, Leproux A, Baker W B, Busch D R, DeMichele A M, Tchou J, Tromberg B J, Yodh A G: Longitudinal optical monitoring of blood flow in breast tumors during neoadjuvant chemotherapy. Physics in medicine and biology 62 (12): 4637-4653,2017.

Basta Marten N, Wu Liza C, Kanchwala Suhail K, Serletti Joseph M, Tchou Julia C, Kovach Stephen J, Fosnot Joshua, Fischer John P: Reliable prediction of postmastectomy lymphedema: The Risk Assessment Tool Evaluating Lymphedema. American journal of surgery 213 (6): 1125-1133.e1,2017.

Gershuni Victoria, Li Yun R, Williams Austin D, So Alycia, Steel Laura, Carrigan Elena, Tchou Julia: Breast cancer subtype distribution is different in normal weight, overweight, and obese women. Breast cancer research and treatment 163 (2): 375-381,2017.

Svoronos Nikolaos, Perales-Puchalt Alfredo, Allegrezza Michael J, Rutkowski Melanie R, Payne Kyle K, Tesone Amelia J, Nguyen Jenny M, Curiel Tyler J, Cadungog Mark G, Singhal Sunil, Eruslanov Evgeniy B, Zhang Paul, Tchou Julia, Zhang Rugang, Conejo-Garcia Jose R: Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells. Cancer discovery 7 (1): 72-85,2017.

Perales-Puchalt Alfredo, Svoronos Nikolaos, Rutkowski Melanie R, Allegrezza Michael J, Tesone Amelia J, Payne Kyle K, Wickramasinghe Jayamanna, Nguyen Jenny M, O'Brien Shane W, Gumireddy Kiranmai, Huang Qihong, Cadungog Mark G, Connolly Denise C, Tchou Julia, Curiel Tyler J, Conejo-Garcia Jose R: Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target. Clinical cancer research : an official journal of the American Association for Cancer Research 23 (2): 441-453,2017.

Academic Contact Info

Division of Endocrine & Oncologic Surgery
3400 Civic Center Boulevard
3rd Floor West

Philadelphia, PA 19104-4283
Phone: (215) 615-7575
Patient appointments: 800-789-7366 (PENN)

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