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Judith A. O'Donnell, MD

Judith A. O'Donnell, MD Physician

Director, Department of Infection Prevention and Control, Penn Presbyterian Medical Center Hospital Epidemiologist, Penn Presbyterian Medical Center Section Chief, Division of Infectious Diseases, Penn Presbyterian Medical Center Professor of Clinical Medicine

Dr. O'Donnell is employed by Penn Medicine.

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About Dr. Judith A. O'Donnell

Recognized by America's Top Doctors 2015 – 2017

Recognized by Best Doctors in America 2003, 2004, 2007 - 2012, 2015 - 2018

Recognized in Philadelphia magazine's annual Top Docs issues for 2018 and 2019

Clinical Specialties


  • Infectious Diseases

Programs & Centers:

Board Certification:

  • Infectious Disease, 1994

Clinical Expertise:

  • AIDS
  • Anal Pap Smear
  • Antiretroviral Salvage Therapy
  • Aspergillosis
  • Bone Infection (Osteomyelitis)
  • C. Difficile (Clostridium Difficile Diarrhea)
  • Cellulitis
  • Encephalitis
  • Fever of Unknown Origin
  • Flu (Influenza)
  • Flu Shot Vaccination
  • Fungal Meningitis
  • Fungemia
  • Genital Warts (Condyloma Acuminatum)
  • Gonorrhea
  • Hepatitis
  • Hepatitis A Vaccination
  • Hepatitis B
  • Hepatitis B Vaccination
  • Hepatitis C
  • Herpes Simplex Virus (HSV)
  • Histoplasmosis
  • HIV and AIDS
  • HPV Vaccination
  • Human Papilloma Virus
  • Japanese Encephalitis Vaccination
  • Joint Infection
  • Lyme Disease
  • Lymphogranuloma Venereum
  • Malaria
  • Measles Vaccination
  • Meningitis
  • Meningitis Vaccination
  • Menningococcal Vaccine
  • MMR Vaccine
  • Mycobacterium
  • Mycobacterium Avium Complex
  • Mycoplasma
  • Mycosis
  • Parasitic Diseases
  • Pneumonia
  • Pneumonia Vaccination
  • Polio Vaccination
  • Pre-Exposure Prophylaxis
  • Prosthetic Joint Infection
  • Pyelonephritis
  • Rabies Vaccination
  • Sexually Transmitted Diseases (STD)
  • Shingles
  • Shingles Vaccination
  • Staph Infection
  • Swollen Lymph Nodes
  • Syphilis
  • Transplant Related Infection
  • Travel Medicine
  • Travel Vaccination
  • Travelers' Diarrhea
  • Tropical Medicine
  • Tuberculosis (TB)
  • Tuberculosis Testing
  • Typhoid Fever Vaccination
  • Viral Encephalitis
  • Viral Meningitis
  • Wound Infection
  • Yellow Fever Vaccination
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Temple University School of Medicine
Residency: Temple University Hospital
Fellowship: Temple University Hospital


Baltimore STD/HIV Prevention Training Center, Baltimore, MD, Local Infectious Diseases Society of America (IDSA), National Society for Healthcare Epidemiology of America (SHEA), National

Hospital Affiliation

Dr. O'Donnell is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

Gelone SP, Pacetti S, O'Donnell JA: Principles of Antimicrobial Therapy Pharmacotherapeutics for Advanced Practice: A Practical Approach, Fourth Edition : 111-134,2017.

See I, Chang J, Gualandi N, Buser GL, Rohrbach P, Smeltz DA, Bellush MJ, Coffin SE, Gould JM, Hess D, Hennessey P, Hubbard S, Kiernan A, O'Donnell J, Pegues DA, Miller JR, Magill SS: Clinical Correlates of Surveillance Events Detected by National Healthcare Safety Network Pneumonia and Lower Respiratory Infection Definitions-Pennsylvania, 2011-2012 Infect Control Hosp Epidemiol 37 (7): 818-824,2016.

Mull N, Feiler A, Dutcher L, Patel N, Major-Joynes B, Sitha D, Alby K, O'Donnell JA, Pegues DA, Mitchell MD, Cavella A and Umscheid CA: Development and implementation of an evidence-based pathway for the evaluation of catheter-associated UTI (CAUTI) in an academic health system Society of Hospital Medicine Annual Meeting, San Diego,CA : 2016.

Horneff JG3rd, Hsu JE, Voleti PB, O'Donnell J, Huffman GR: Propionibacterium acnes infection in shoulder arthroscopy patients with postoperative pain J Shoulder and Elbow Surg 24 (6): 838-843,2015.

O’Donnell J, Ryan G, Glaser L, Alby K, Bernard D: Mycobacterium avium complex Pseudo-outbreak Investigation in Patients Undergoing Bronchoscopy Society for Healthcare Epidemiology (SHEA) Spring 2015 Conference: Science Guiding Prevention Orlando, FL : 2015.

Amanda Binkley, Danielle Evans, Christopher Edwards, Tanya Dougherty, Judith A. O'Donnell, Nishaminy Kasbekar: Evaluation of the Impact of a Clinical Decision Support Tool and Pharmacist Telephone Consultation within 48 hours of Discharge on Unscheduled Emergency Department Encounters for Skin and Soft Tissue Infections Infectious Diseases Society of America (IDSA) ID Week 2014 Conference Philadelphia, PA : 2014.

See I, Chang J, Gualandi N, Buser G, Rohrbach P, Smith DA, Bellush MJ, Coffin SE, Gould JM, Hess D, Hennessey P, Hubbard S, Kiernan A, O'Donnell JA, Pegues DA, Miller J, Magill S: Evaluating Clinical Credibility of Surveillance Definitions for Healthcare-Associated Pneumonia and Lower Respiratory Tract Infections Infectious Diseases Society of America (IDSA) ID Week 2014 Conference Philadelphia, PA : 2014.

Cimino C, Binkley A, Edwards C, Maniglia R, Kasbaker N, Evans D, Dougherty T, Boedec C: Impact of a Clinical Decision Support Tool in The Emergency Department on Antimicrobial Prescribing Patterns for the treatment of Pneumonia Infectious Diseases Society of America (IDSA) ID Week 2014 Conference, Philadelphia PA : 2014.

O’Donnell JA, Gelone SP, Safdar A: Topical Antibacterials Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, Eighth Edition : 452-62,2014.

Sewick A, Makani A, Wu C, O'Donnell J, Baldwin KD, Lee GC: Does dual antibiotic prophylaxis better prevent surgical site infections in total joint arthroplasty? Clin Orthop Relat Res 470 (10): 2702-2707,2012.

Academic Contact Info

Division of Infectious Diseases
Penn Presbyterian Medical Center
3910 Powelton Avenue, 4th floor

Philadelphia, PA 19104
Phone: (215) 662-8729
Patient appointments: 800-789-7366 (PENN)

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