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Juan E. Grunwald, MD

Juan E. Grunwald, MD Physician

Director, CATT Reading Center
Director, Vivian S. Lasko Oculovascular Research Center
Professor of Ophthalmology at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia

Languages spoken:

  • Hebrew
  • Spanish

Dr. Grunwald is a Penn Medicine employed physician.

Clinical Specialties


  • Ophthalmology

Programs & Centers:

Board Certification:

  • Ophthalmology, 1983

Clinical Expertise:

  • Age-related Macular Degeneration (AMG)
  • Diabetic Retinopathy
  • Diabetic Retinopathy - Laser
  • Eye Floaters
  • Macular Degneration
  • Ocular Hemodynamics
  • Retinal Degeneration
  • Retinal Disorders
  • Retinal Laser Therapy
  • Retinal Vascular Disease

Description of Clinical Expertise

Dr. Grunwald cares for and treats patients with age-related macular degeneration, diabetic retinopathy and retinal vascular diseases at the following locations: Scheie Eye Institute, Hospital of the University of Pennsylvania, Penn Medicine at Radnor, Mercy Fitzgerald Hospital and the Veterans’ Administration Medical Center.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Superior Vision Benefit Mgmt, Inc (Block Vision)
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Residency: Hasharon Hospital
Medical School: Sackler School of Medicine
Residency: Beilinson Medical Center


American Academy of Ophthalmology, National American Association for the Advancement of Science, National American Diabetes Association, National American Medical Association, National Association for Research in Vision and Ophthalmology, International College of Physicians of Philadelphia, Local Delaware Valley Ophthalmologic Society, Local European Association for the Study of Diabetes, International International Society for Eye Research, National Israel Science Foundation, International Macula Society, National National Society to Prevent Blindness, National Pan-American Association of Ophthalmology, International Pennsylvania Academy of Ophthalmology, Local Pennsylvania Medical Society, Local Philadelphia County Medical Society, Local The Welcome Trust Limited, London, United Kingdom, International

Hospital Affiliation

Dr. Grunwald is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Dr. Grunwald is world renowned for his research on blood flow in the retina. He has helped to develop techniques to measure the circulation in the eye. In his laboratory, the Vivian Simkins Lasko Retinal Vascular Research Laboratory, non-invasive state of the art technology is employed to study the role of circulatory changes in the development of vision-threatening eye diseases such as age-related macular degeneration (AMD), diabetic retinopathy, glaucoma, retinitis pigmentosa, and others and the pharmacologic effects of medications on the human ocular vasculature and its circulation.

Clinical Trials
Dr. Grunwald is an investigator on the following trials:
•Complications of Age-Related Macular Degeneration Prevention Trial (CAPT)
•The Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)
•Retinopathy in Chronic Renal Insufficiency (RCRIC)

He is the Principal Investigator of two grants that will quantitate changes occurring in the retina due to diabetic retinopathy, systemic hypertension and age-related macular degeneration.

Age-related macular degeneration (AMD), choroidal circulation, diabetic retinopathy, ocular vasculature, optic nerve blood flow, pharmacologic effects, retina, retinal circulation, retinal vasculature

Selected Publications:

Cuilla TA, Ying GS, Maguire MG, Martin DF, Jaffe GJ, Grunwald JE, Daniel E, Toth CA: Influence of the Vitreomacular Interface on Treatment Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology 122 (6): 1203-11,2015.

Altaweel MM, Daniel E, Martin DF, Mittra RA, Grunwald JE, Lai MM, Melamud A, Morse LS, Huang J, Ferris FL, Fine SL, Maguire MG: Outcomes of eyes with lesions composed of >50% blood in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 122 (2): 391-398.e5,2015.

Gewaily DY, Grunwald JE, Pistilli M, Ying GS, Maguire MG, Daniel E, Ostroff CP, Fine SL: Delayed patchy choroidal filling in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). American journal of ophthalmology 158 (3): 525-31.e2,2014.

Ricardo AC, Grunwald JE, Parvathaneni S, Goodin S, Ching A, Lash JP: Retinopathy and CKD as predictors of all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 1988-1994. American journal of kidney diseases : the official journal of the National Kidney Foundation 64 (2): 198-203,2014.

Ying GS, Kim BJ, Maguire MG, Huang J, Daniel E, Jaffe GJ, Grunwald JE, Blinder KJ, Flaxel CJ, Rahhal F, Regillo C, Martin DF: Sustained visual acuity loss in the comparison of age-related macular degeneration treatments trials. JAMA ophthalmology 132 (8): 915-21,2014.

Daniel E, Toth CA, Grunwald JE, Jaffe GJ, Martin DF, Fine SL, Huang J, Ying GS, Hagstrom SA, Winter K, Maguire MG: Risk of scar in the comparison of age-related macular degeneration treatments trials. Ophthalmology 121 (3): 656-66,2014.

Scialla JJ, Xie H, Rahman M, Anderson AH, Isakova T, Ojo A, Zhang , Nessel L, Hamano T, Grunwald JE, Raj DS, Yang W, He J, Lash JP, Go AS, Kusek JW, Feldman H, Wolf M: Fibroblast growth factor-23 and cardiovascular events in CKD. Journal of the American Society of Nephrology : JASN 25 (2): 349-60,2014.

Maguire MG, Daniel E, Shah AR, Grunwald JE, Hagstrom SA, Avery RL, Huang J, Martin RW, Roth DB, Castellarin AA, Bakri SJ, Fine SL, Martin DF: Incidence of Choroidal Neovascularization in the Fellow Eye in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 120 (10): 2035-2041,2013.

Grunwald JE, Daniel E, Huang J, Ying GS, Maguire MG, Toth CA, Jaffe GJ, Fine SL, Blodi B, Klein ML, Martin AA, Hagstrom SA, Martin DF: Risk of Geographic Atrophy in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 121 (1): 150-61,2013.

Jaffe GJ, Martin DF, Toth CA, Daniel E, Maguire MG, Ying GS, Grunwald JE, Huang J: Macular Morphology and Visual Acuity in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 120 (9): 1860-70,2013.

View all publications

Academic Contact Info

Scheie Eye Institute
51 North 39th Street

Philadelphia, PA 19104
Patient appointments: 800-789-PENN (7366)

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