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Jose L. Pascual, MD

Jose L. Pascual, MD Physician

Associate Professor of Surgery at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia Associate Professor of Neurosurgery

Languages spoken:

  • French
  • Spanish

Dr. Pascual is employed by Penn Medicine.

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Clinical Specialties


  • Trauma Surgery

Programs & Centers:

Board Certification:

  • Surgery, 2006
  • Surgical Critical Care, 2007

Clinical Expertise:

  • Emergency General Surgery
  • Emergency Trauma
  • Surgical Critical Care

Description of Clinical Expertise

Jose Pascual is an intensivist/surgeon at the University Of Pennsylvania, board certified in the US/Canada. He finished his fellowship in 2007 and his basic science PhD in resuscitation immunobiology, at McGill, in 2005. His thesis investigated the salutary effects of immunemodulating fluids in shock.

As faculty of Medical and Nursing Schools, Jose teaches students, residents, fellows and advance practice providers in several didactic and skills courses. However, most notable is his role as research mentor for medical, nursing and undergraduate students raising questions at the bedside and attempting to answer them through clinical or basic science research projects. In the last 5 years, Jose has mentored 23 research trainees, several of whom have won awards at national/international scientific meetings.

Jose Pascual’s research interests include Traumatic Brain Injury, shock and ICU education through simulation and patient safety initiatives. His TBI laboratory studies immune responses to injury through intravital microscopy of the cerebral microcirculation investigating the role of the neutrophil in injury and shock.

Jose has launched several ICU educational initiatives using simulation integrated within the ICU to teach day-to-day emergent event management by the multidisciplinary team (NPs, MDs, nurses, pharmacists) through learning from errors or near misses. Initiatives relating to videorecorded simulator-generated or real emergent events have been integrated in ICU Quality Improvement efforts and also published.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Ottawa
Residency: McGill University Hospitals
Fellowship: Hospital of the University of Pennsylvania


American Association for the Surgery of Trauma, National American Board of Surgery, National American College of Surgeons, National Association for Academic Surgery, National Canadian Association of General Surgeons, National Eastern Association for the Surgery of Trauma, National International Association for Trauma Surgery & Intensive Care, International International Society of Surgery, International National Neurotrauma Society, National Pan-American Trauma Society, National Pennsylvania Chapter American College of Surgeons, Local Royal College of Physicians & Surgeons of Canada, National Society of Critical Care Medicine, National Society of Critical Care Medicine, National Trauma Association of Canada, National

Hospital Affiliation

Dr. Pascual is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Jose Pascual is a clinical surgeon specialized in trauma and critical care who has a special interest in shock and head injury. His research interests are shared in basic science research where he evaluates, in vivo, through intravital microscopy the real time microcirculation of pia on live rodent brains. He seeks to learn how a variety of insults including head injury and shock affect the microcirculation and how different management strategies influence these changes. This basic science work is translated into several clinical projects both retrospective and prospective evaluating the effects of different osmotherapeutic agents in traumatic brain injured patients as well as the immunemodulating effects of different resuscitation fluids in different forms of shock.

Selected Publications:

Acker Andrew; Leonard Jennifer; Seamon Mark J; Holena Daniel N; Pascual Jose; Smith Brian P; Reilly Patrick M; Martin Niels D: Leaving contaminated trauma laparotomy wounds open reduces wound infections but does not add value Journal of surgical research 232 : 450-455,2018.

Martin N, Pascual JL, Crowe D, Toevs C, Cereda MF, Mikkelsen M, Kaplan LJ.: Comfort at the crossroads: Service, therapy and emotional support animals in the intensive care unit and at the end-of-life. J Trauma Acute Care Surg. : 2018.

Nagata K, Suto Y, Cognetti J, Browne KD, Kumasaka K, Johnson VE, Kaplan L, Marks J, Smith DH, Pascual JL.: Early low-anticoagulant desulfated heparin after traumatic brain injury: Reduced brain edema and leukocyte mobilization is associated with improved watermaze learning ability weeks after injury. J Trauma Acute Care Surg : 2018.

Nunn AM, Hatchimonji JS, Holena DN, Seamon MJ, Smith BP, Kaplan LJ, Martin ND, Reilly PM, Schwab CW, Pascual JL.: Boardng ICU patients: Are you rounding practices subpar? American Journal of Surgery 215 : 669-674,2018.

Suto Y, Nagata K, Ahmed SM, Jacovides C, Browne KD, Cognetti J, Weber MT, Johnson VE, Leone R, Kaplan LJ, Smith DH, Pascual JL.: A CONCOMITANT BONE FRACTURE DELAYS COGNITIVE RECOVERY FROM TRAUMATIC BRAIN INJURY. J Trauma Acute Care Surg : 2018.

Moore S, Weiss B, Pascual JL, Kaplan LJ.: Management of Acute Respiratory Failure in the Patient with Sepsis or Septic Shock. Surg Infect (Larchmt). : 2018.

Montmany S, Pascual JL, Kim PK, McMaster J, Pallisera A, Rebasa P, Luna A, Navarro S.: American vs. European Trauma Centers: A Comparison of Preventable Deaths.[Comparacion de la mortalidad evitable de un trauma center Americano vs. un centro de referencia europeo] Cirugia Espanola 95 : 2017.

Nagata K, Suto Y, Cognetti J, Browne KD, Kumasaka K, Johnson V, Kaplan L, Marks JA, Smith DH, Pascual JL.: Non-Anticoagulant desulfated heparin acutely reduces leukocyte mobilization and brain edema and improves watermaze learning ability weeks after traumatic brain injury. Podium presentation at the 76th Annual Meeting of the American Association for the Surgery of Trauma, Baltimore, MD. : 2017.

Sherma A, Sinha S, Oselkin M, Pascual J, Schuster J: External carotid pseudoaneurysm due to wound vacuum placement after self-inflicted shotgun blast to face. Podium at 3rd Annual Critical Care Spectacular Case Presentation Competition, Philadelphia Drinker Society,Philadelphia, PA : 2017.

Resnick S, Seamon MJ, Holena DH, Pascual JL, Reilly PM, Martin ND.: Early Declaration of Death by Neurologic Criteria Results in Greater Organ Donor Potential J Surg Res : 2017.

Academic Contact Info

Division of Trauma & Surgical Critical Care
Perelman School of Medicine at the University of Pennsylvania
51 North 39th St,MOB 1st floor, Suite 120, Room 108

Philadelphia, PA 19104
Phone: (215) 662-7323
Patient appointments: 800-789-7366 (PENN)

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