Description of Research Expertise:
Jose Pascual is a clinical surgeon specialized in trauma and critical care who has a special interest in shock and head injury. His research interests are shared in basic science research where he evaluates, in vivo, through intravital microscopy the real time microcirculation of pia on live rodent brains. He seeks to learn how a variety of insults including head injury and shock affect the microcirculation and how different management strategies influence these changes. This basic science work is translated into several clinical projects both retrospective and prospective evaluating the effects of different osmotherapeutic agents in traumatic brain injured patients as well as the immunemodulating effects of different resuscitation fluids in different forms of shock.
Sharoky C, Martin ND, Smith BP, Pascual JL, Kaplan LJ, Reilly PM, Holena DN: The Location and Timing of Failure to Rescue Events Across a Statewide Trauma System Corresponding Journal of Surgical Research 235 : 529-535,2019.
Suto Y, Nagata K, Ahmed SY, Jacovides CL, Browne KD, Cognetti J, Johnson VE, Leone R, Kaplan LJ, Smith DH, Pascual JL: Cerebral edema and neurological recovery after traumatic brain injury (TBI) is worsened if accompanied by a concomitant long bone fracture J Neurotrauma 36 (4): 2019.
Asfaw SH, Martin ND, Seamon MJ, Pascual JL, Reilly PM, Holena DN: Is It Cool to Cool Postcardiac Arrest Trauma Patients? American Surgeon : 2019.
Jacovides C, Ahmed S, Suto Y, Paris A, Leone R, McCarry J, Christofidou-Solomidou M, Kaplan LJ, Smith D, Holena DN, Schwab CW, Pascual JL: An Infectious Pulmonary Insult Post-TBI Worsens Subsequent Spatial Learning and Neurological Outcomes Podium presentation, Eastern Association for the Surgery of Trauma 32nd Annual Scientific Assembly, Austin, TX : 2019.
Suto Y, Ahmed S, Jacovides C, Roche A, Weber M, Johnson V, Leone R, Kaplan LJ, Smith D, Ogawa T, Pascual JL: A concomitant long bone fracture worsens traumatic brain injury recovery: a time dependent process Podium presentation, Eastern Association for the Surgery of Trauma 32nd Annual Scientific Assembly, Austin, TX : 2019.
Fernandez-Moure J, Pascual JL, Martin ND, Rogers H, Kaplan LJ: Emergency response teams in and outside of medicine—structurally crafted to be worlds apart Journal of Trauma and Acute Care Surgery 86 (1): 134-140,2019.
Matsushima K, Leichtle SW, Wild J, Young K, Chang G, Lomangino CD, Massetti J, Glass N, Livingston DH, O'Bosky K, Chan J, Cullinane DC, Rippey KA, Sharma J, Nahmias J, Grigorian A, Allen S, Armen SB, Berne JD, Mederos D, Pascual JL, Resnick S, Bholat O, Ostry L, Garcia LJ, Vecchio RR, Winston ES, Sabour AF, Demetriades D: Anticoagulation therapy in patients with traumatic brain injury (ACT-TBI): An EAST Multicenter Prospective Study Podium presentation, Eastern Association for the Surgery of Trauma 32nd Annual Scientific Assembly, Austin, TX : 2019.
Acker A, Leonard J, Seamon MJ, Holena DN, Pascual JL, Smith BP, Reilly PM, Martin ND: Leaving contaminated trauma laparotomy wounds open reduces wound infections but does not add value Journal of Surgical Research 232 : 450-455,2018.
Fall MB, Pascual JL, Peifer HG, Di Taranti LJ, Collard ML, Jablonski J, Gutsche JT, Halpern SD, Barg FK, Fleisher LA: A Partially Structured Postoperative Handoff Protocol Improves Communication in 2 Mixed Surgical Intensive Care Unites: Findings From the Handoffs and Transitions in Critical Care (HATRICC) Prospective Cohort Study Lane Ann Surg : 2018.
Jacovides C, Ahmed SM, Suto Y, Paris AJ, Weber R, Johnson VE, Christofidu-Solomidou M, Kaplan LJ, Smith DH, Holena DN, Schwab CW, Pascual JL: Does a lung infection after brain injury worsen early brain inflammation and subsequent neurological recovery? Oral Abstract, American Association for the Surgery of Trauma 77th Annual Meeting, San Diego, CA : 2018.