Description of Research Expertise:
Jose Pascual is a clinical surgeon specialized in trauma and critical care who has a special interest in shock and head injury. His research interests are shared in basic science research where he evaluates, in vivo, through intravital microscopy the real time microcirculation of pia on live rodent brains. He seeks to learn how a variety of insults including head injury and shock affect the microcirculation and how different management strategies influence these changes. This basic science work is translated into several clinical projects both retrospective and prospective evaluating the effects of different osmotherapeutic agents in traumatic brain injured patients as well as the immunemodulating effects of different resuscitation fluids in different forms of shock.
Pascual JL, Cannon J.: Hemorrhagic Shock: Recognition, Pathophysiology and Management. Nova Science Publishers, Inc., New York, NY. : 2017.
Li S, Eisenstadt R, Kumasaka K, Johnson VE, Marks J, Nagata K, Browne KD, Smith DH, Pascual JL.: Does enoxaparin interfere with HMGB1 signaling after TBI? A potential mechanism for reduced cerebral edema and hastened neurological recovery. J Trauma Acute Care Surg : 2016 (accepted for publication) .
Chung JC, Earl-Royal E, Delgado MK, Pascual JL, Reilly PM, Wiebe DJ, Holena DN.: Where We Fail: Location and Timing of Failure to Rescue in Trauma. Am Surgeon, : 2016.
Hersperger S, Becker A, Heiderich G, Smith B, Holena D, Schutz A, Mancini DJ, Kumar HRN, Mook M, Holland S, Motuk S, Martin N, Reilly PM, Kim P, Pascual JL.: BECOMING A TRAUMA CENTER OVERNIGHT: Using Simulation to Train Seasoned Yet Trauma-Naïve Providers Prior to Becoming Trauma Providers. Quick Shot, 68th Annual Meeting of The Southwestern Surgical Congress, Coronado, CA : 2016.
Hatchimonji JS, Nunn AM, Holena DN, Smith BP, Martin ND, Reilly PM, Schwab CW, Pascual JL.: BOARDING ICU PATIENTS: ARE OUR ROUNDING PRACTICES SUBPAR? Quick Shot, 68th Annual Meeting of The Southwestern Surgical Congress, Coronado, CA : 2016.
Kaufman EJ, Wiebe DJ, Martin ND, Pascual JL, Reilly PM, Holena DN: Variation in ICU Utilization and Mortality After Blunt Splenic Injury. Accepted to J Surg Res, : 2016.
Barry ME, Hochman BR, Lane-Fall MB, Zappile D, Holena DN, Smith BP, Kaplan LJ, Huffenberger A, Reilly PM, Pascual JL.: Operating room-to ICU handoffs captured on video: Are nighttime transitions more dangerous? Submitted to The Joint Commission Journal on Quality and Patient Safety : 2016.
Lane-Fall M, Pascual JL.: Developing a standardized OR to ICU handoff process. Poster at the 45th Congress of SCCM, Orlando, FL, : 2016.
Jablonski J, Pascual JL, Martin N.: Do antipsychotics improve ICU outcomes in patients with delirium? Poster at the 45th Congress of SCCM, Orlando, FL, : 2016.
ND Martin, SP Patel, K Chreiman, J Pascual, DN Holena, B Braslow, PM Reilly, L Kaplan.: Surgery for Patients In Extremis: Reasonable Care or Surgical Futility? Quickshot, 11th Annual Academic Surgical Congress, Jacksonville, FL : 2016.