General Pediatrics
Jonathan M. Spergel, MD, PhD
Independent provider
Accepting new patients
Sees newborns through age 18
CHOP Specialty Care, Princeton at Plainsboro

About me

  • Professor of Pediatrics (Allergy/Immunology) at the Children's Hospital of Philadelphia

Education and training

  • Medical School: Mount Sinai School of Medicine
  • Residency: Yale-New Haven Hospital
  • Fellowship: Children's Hospital of Boston

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Princeton Medical Center: On the medical staff, but does not have privileges to treat patients in the hospital.
Dr. Spergel is an independent physician who is not employed by Penn Medicine.

Qualifications and experience

Treatments and Conditions

My research

Zhou X, Dunham D, Sindher SB, Long A, Fernandes A, Chang I, Assa'ad A, Pongracic J, Spergel JM, Tam J, Tilles S, Wang J, Boyd SD, Chinthrajah RS, Nadeau KC. HLA-DR(+) regulatory T cells and IL-10 are associated with success or failure of desensitization outcomes , Allergy: 2025


Paller AS, Eichenfield LF, Irvine AD, Flohr C, Wollenberg A, Barbarot S, Bangert C, Spergel JM, Selfridge A, Biswas P, Fan H, Alderfer J, Watkins M, Koppensteiner H. Integrated Efficacy and Safety Analysis of Abrocitinib in Adolescents With Moderate-to-Severe Atopic Dermatitis , Allergy: 2025


Dupuis R, Spergel JM, Brown-Whitehorn TF, Troxel AB, Kenney EL, Block JP, Feuerstein-Simon R, Marti XL, Mollen CJ, Meisel ZF, Volpp KG, Gortmaker SL, Cannuscio CC. Incidence of food allergic reactions among adolescents engaged in food allergy management , Ann Allergy Asthma Immunol: 2025


Chidambaram AG, Cielo CM, Chervoneva I, Spergel JM, Tapia IE. Nasal biomarker inflammatory profile in response to intranasal corticosteroids in pediatric obstructive sleep apnea syndrome , J Clin Sleep Med: 2025


Chinthrajah RS, Sindher SB, Nadeau KC, Leflein JG, Spergel JM, Petroni DH, Jones SM, Casale TB, Wang J, Carr WW, Shreffler WG, Wood RA, Wambre E, Liu J, Akinlade B, Atanasio A, Orengo JM, Hamilton JD, Kamal MA, Hooper AT, Patel K, Laws E, Mannent LP, Adelman DC, Ratnayake A, Radin AR. Dupilumab as an Adjunct to Oral Immunotherapy in Pediatric Patients With Peanut Allergy , Allergy: 2025


Kliewer KL, Abonia JP, Aceves SS, Atkins D, Bonis PA, Capocelli KE, Chehade M, Collins MH, Dellon ES, Fei L, Furuta GT, Gupta SK, Kagalwalla A, Leung J, Mir S, Mukkada VA, Pesek R, Rosenberg C, Shoda T, Spergel JM, Sun Q, Wechsler JB, Yang GY, Rothenberg ME. One-food versus 4-food elimination diet for pediatric eosinophilic esophagitis: A multisite randomized trial , J Allergy Clin Immunol, 155: 2025,520-32


Dilollo J, Hu A, Qu H, Canziani KE, Clement RL, McCright SJ, Shreffler WG, Hakonarson H, Spergel JM, Cerosaletti K, Hill DA. A molecular basis for milk allergen immune recognition in eosinophilic esophagitis , J Allergy Clin Immunol: 2025


Spergel JM, Chehade M, Dellon ES, Bredenoord AJ, Sun X, Glotfelty L, Shabbir A, Tilton ST, McCann E. Dupilumab Improves Health-Related Quality of Life and a Range of Symptoms in Patients With Eosinophilic Esophagitis , Am J Gastroenterol, 119: 2024,2398-2407


Kim S, Ben-Baruch Morgenstern N, Osonoi K, Aceves SS, Arva NC, Chehade M, Collins MH, Dellon ES, Falk GW, Furuta GT, Gonsalves NP, Gupta SK, Hirano I, Hiremath G, Katzka DA, Khoury P, Leung J, Pesek R, Peterson KA, Pletneva MA, Spergel JM, Wechsler JB, Yang GY, Rothenberg ME, Shoda T. Nonepithelial Gene Expression Correlates With Symptom Severity in Adults With Eosinophilic Esophagitis , J Allergy Clin Immunol Pract, 12(12): 2024,3346-3351


Martin LJ, Zhang X, Chehade M, Davis CM, Dellon ES, Falk GW, Gupta SK, Hirano I, Hiremath GS, Katzka DA, Khoury P, Leung J, Menard-Katcher P, Gonsalves N, Pesek RD, Spergel JM, Wechsler JB, Kliewer K, Arva NC, Collins MH, Pletneva M, Yang GY, Furuta GT, Rothenberg ME, Aceves SS. Long-term durability between parent and child patient-reported outcomes in eosinophilic esophagitis , J Allergy Clin Immunol, 154(5): 2024,1232-1240