- Aicardi-Goutieres syndrome (AGS)
- Autoinflammatory disease
- Cerebroretinal vasculopathy (CRV)
- COPA syndrome
- Cryopyrin associated periodic syndrome (CAPS)
- Familial Mediterranean fever
- Hereditary endotheliopathy, retinopahy, nephropathy and stroke (HERNS)
- IgG4-related disease (IgG4-RD)
- Retinal vasculopathy with cerebral leukoencephalopathy (RVCL)
- Still's disease
- STING-associated vasculopathy with onset in infancy (SAVI)
- TNF receptor associated periodic syndrome (TRAPS)
Jonathan J Miner, MD, PhD
Rheumatology
Accepting new patients
Sees patients age 18 and up
Penn Rheumatology Perelman
Penn Medicine Provider
About me
- Associate Professor of Medicine (Rheumatology)
- Associate Professor of Medicine in Microbiology
My education and training
- Medical School: University of Oklahoma
- Residency: Barnes-Jewish Hospital - Washington University, St. Louis
- Fellowship: Barnes-Jewish Hospital - Washington University, St. Louis
Spoken languages
English
English
Insurance accepted
Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.
- Aetna Advantra Cares D-SNP
- Aetna Advantra Credit Value
- Aetna Advantra Eagle HMO
- Aetna Advantra Eagle POS
- Aetna Advantra Premier Plus PPO
- Aetna Advantra Value
- Aetna Advantra Value Plus
- Aetna APCN Plus (Multi-Tier)
- Aetna Better Health Kids (CHIP) - DH Only
- Aetna Flexible Five
- Aetna Freedom Core
- Aetna Gold
- Aetna HMO
- Aetna Philly Prime
- Aetna POS
- Aetna PPO APCN
- Aetna Premier
- Aetna Premier Plus
- Aetna Savings Plus
- Aetna Signature Administrators
- Aetna Student Health Plan PPO
- Aetna Upfront Advantage
- First Health HMO
- First Health POS
- First Health PPO
- Meritain - Aramark (Other)
- Meritain - Aramark (Pennsylvania Premier Medical Plan)
- Americhealth Caritas of PA VIP - LGH Only
- Amerihealth Caritas (Transplant patients only)
- Amerihealth Caritas of PA - LGH Only
- Centivo EPO
- Cigna Healthcare EPO
- Cigna Healthcare HMO
- Cigna Healthcare POS
- Cigna Healthcare PPO
- Claim Watcher (Homestead/ INDECs) Open Access
- Clover Health Choice
- Clover Health Choice Value PPO
- Clover Health Classic HMO
- Clover Health Value
Locations
Penn Medicine hospital privileges
- Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
- Pennsylvania Hospital: Has privileges to treat patients in the hospital.
- Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Qualifications and experience
- Rheumatology, 2015
- American Association of Immunologists, National
- American College of Rheumatology, National
- American Society for Clinical Investigation, National
- American Society for Virology, National
- American Society of Gene and Cell Therapy, National
- Clayco Foundation Scientific Advisory Board, National
- International Cytokine and Interferon Society, International
- NIH, National Institute of Allergy and Infectious Diseases, National
- NIH, National Institute of Arthritis Musculoskeletal and Skin Diseases, National
- RVCL Research Center at Penn, Local
Treatments and conditions
Research
Publications
Poddar S, Chauvin SD, Archer CH, Qian W, Castillo-Badillo J, Yin X, Disbennett WM, Miner A, Holley JA, Naismith T, Stinson WA, Wei X, Ning Y, Fu J, Ochoa TA, Surve N, Zaver S A, Wodzanowski KA, Balka KR, Venkatraman R, Liu C, Rome K, Bailis W, Shiba Y, Cherry S, Shin S, Semenkovich CF, De Nardo D, Yoh S, Roberson EDO, Chanda SK, Kast DJ, and Miner JJ. ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation. , Cell: 2025
Chauvin SD, Holley JA, Poddar S, Miner CA, Kumble L, Fu J, Laue-Gizzi H, Hardy TA, Miner JJ. Prime editor gene therapy and TREX1 mosaicism in retinal vasculopathy with cerebral leukoencephalopathy. , J Clin Immunol, 41(1): 2024,54
Chauvin SD, Ando S, Holley JA, Sugie A, Zhao FR, Poddar S, Kato R, Miner CA, Nitta Y, Krishnamurthy SR, Saito R, Ning Y, Hatano Y, Kitahara S, Koide S, Stinson WA, Fu J, Surve N, Kumble L, Qian W, Polishchuk O, Andhey PS, Chiang C, Liu G, Colombeau L, Rodriguez R, Manel N, Kakita A, Artyomov MN, Schultz DC, Coates PT, Roberson EDO, Belkaid Y, Greenberg RA, Cherry S, Gack MU, Hardy T, Onodera O, Kato T, Miner JJ. Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans. , Nature Communications, 15(1): 2024,4696
Miner JJ, Fitzgerald KA. A path towards personalized medicine for autoinflammatory and related diseases , Nature Reviews Rheumatol, 19(3): 2023,182-189
Chauvin SD, Stinson WA, Platt DJ, Poddar S, Miner JJ. Regulation of cGAS and STING signaling during inflammation and infection , Journal of Biological Chemistry, 299(7): 2023,104866
Platt DJ, Lawrence D, Qian W, Rodger R, Schriefer L, Miner CA, Menos AM, Kennedy EA, Peterson ST, Stinson WA, Baldridge MT, Miner, JJ Transferrable protection by gut microbes against STING-associated lung disease , Cell Rep, 35(6): 2021,109133
Bennion BG, Croft CA, Ai TL, Qian W, Menos AM, Miner CA, Fremond ML, Doisne JM, Andhey PS, Platt DJ, Bando JK, Wang ER, Luksch H, Molina TJ, Robison EDO, Artyomov MN, Rosen-Wolff A, Colonna M, Rieux-Laucat F, Di Santo JP, Neven B, Miner JJ. STING gain-of-function disrupts lymph node organogenesis and innate lymphoid cell development in mice. , Cell Rep, 31(11): 2020,107771
Luksch H, Stinson WA, Platt DJ, Qian W, Kalugotla G, Miner CA, Bennion BG, Gerbaulet A, Rösen-Wolff A, Miner JJ. STING-associated lung disease in mice relies on T cells but not type I interferon , J Allergy Clin Immunol, 144(1): 2019,154-266