Description of Research Expertise:
My research focuses on the multidisciplinary management of head and neck cancers, in particular novel strategies to understand and mitigate the toxicities associated with head and neck radiotherapy. Additionally, I am interested in identifying subsets of patients with HPV+ cancer who may benefit from treatment de-intensification, and conversely, those with high-risk disease who may benefit from novel targeted therapy and/or immunotherapy.
Gamez M, Agarwal M, Hu KS, Lukens JN, Harrison LB: Hypofractionated palliative radiotherapy with concurrent radiosensitizing chemotherapy for advanced head and neck cancer using the QUAD-SHOT regimen Anticancer research : 2017.
Daniel M. Trifiletti, Andrew Smith, Nandita Mitra, Surbhi Grover, John N. Lukens, Roger B. Cohen, Paul Read, William M. Mendenhall, Alexander Lin, Samuel Swisher-McClure: Beyond Positive Margins and Extracapsular Extension: Evaluating the Utilization and Clinical Impact of Postoperative Chemoradiotherapy in Resected Locally Advanced Head and Neck Cancer Journal of Clinical Oncology : 2017.
Eric Ojerholm, J. Nicholas Lukens, Peter H. Ahn, Geoffrey Geiger, Samuel Swisher-McClure, Jason Newman, Ara Chalian, Gregory Weinstein, Bert W. O'Malley Jr., Roger Cohen, Alexander Lin: Benefits of omitting primary site radiotherapy after TORS: only time will tell Practical Radiation Oncology : 2016.
Sharma S, Bekelman J, Lin A, Lukens JN, Roman BR, Mitra N, Swisher-McClure S: Clinical impact of prolonged diagnosis to treatment interval (DTI) among patients with oropharyngeal squamous cell carcinoma Oral Oncology 56 : 17-24,2016.
Annemarie Fernandes, MD
Abigail T. Berman, MD
Rosemarie Mick, MS
Stefan Both, PhD
Kristi Lelionis, MS
John N. Lukens, MD
Edgar Ben-Josef, MD
James M. Metz, MD
John P. Plastaras, MD, PhD: A Prospective Study of Proton Beam Reirradiation for Esophageal Cancer
International Journal of Radiation Oncology, Biology, Physics : 2016.
Sarah A. Milgrom, Shekeab Jauhari, John P. Plastaras, Yago Nieto, Grace L. Smith, Chelsea C. Pinnix, Bouthaina S. Dabaja, Pamela K. Allen, J. Nicholas Lukens, Amit Maity, Yasuhiro Oki, Michelle A. Fanale, and Sunita D. Nasta: A Multi-Institutional Analysis of Peri-Transplant Radiation Therapy in Patients with Relapsed/Refractory Hodgkin Lymphoma Undergoing Autologous Stem Cell Transplantation Cancer : 2016.
Surbhi Grover, Nandita Mitra, Fei Wan, John N. Lukens, Sonam Sharma, Jessica Bauman, Farzad Masroor, Roger B. Cohen, Arati Desai, Kenneth Algazy, Michelle Alonso-Basanta, Peter Ahn, Boon-Keng Kevin Teo, Ara A. Chalian, Gregory S. Weinstein, Bert W. O’Malley, Jr, Alexander Lin: A Single-institution Comparison of Cetuximab, Carboplatin, and Paclitaxel Induction Chemotherapy Followed by Chemoradiation (CRT) Versus CRT for Locally Advanced Squamous Cell Carcinoma of the Head and Neck (LA-SCCHN) American Journal of Clinical Oncology : 2016.
David J. Thomson, Boon-Keng Kevin Teo, Ashley Ong, Khong Wei Ang, Maura Kirk, Peter H. Ahn, John N. Lukens, Samuel Swisher-McClure, Tom Liptrot,
Timothy D. Solberg, Nick J. Slevin, Alexander Lin, MD: The Impact of Anatomic Change on Pencil Beam Scanning in the Treatment
of Oropharynx Cancer International Journal of Particle Therapy 2 (2): 393-403,2015.
Surbhi Grover, Samuel Swisher-McClure, Nandita Mitra, Jiaqi Li, Roger B Cohen, Peter H Ahn, John N Lukens, Ara A Chalian, Gregory S Weinstein, Bert W O'Malley, Jr, Alexander Lin: Total Laryngectomy Versus Larynx Preservation for T4a Larynx Cancer: Patterns of Care and Survival Outcomes International Journal of Radiation Oncology, Biology, Physics 92 (3): 594-601,2015.
Lukens J Nicholas, Lin Alexander, Hahn Stephen M: Proton therapy for head and neck cancer. Current opinion in oncology 27 (3): 165-71,2015.