- Aspirin exacerbated respiratory disease (AERD)
- Aspirin desensitization therapy
John V. Bosso, MD
Otorhinolaryngology
Accepting new patients
Sees patients age 18 and up
Penn Otorhinolaryngology - Head and Neck Surgery Perelman
Penn Medicine Provider
About me
- Medical Director, Penn AERD Center
- Director, Otorhinolaryngology Allergy Clinic
- Professor of Clinical Otorhinolaryngology: Head and Neck Surgery
John V. Bosso, MD, allergist/immunologist and clinical professor, serves as medical director of the Aspirin Exacerbated Respiratory Disease (AERD or Samter’s triad) Center and director of the OTO-Allergy Clinic at Penn Medicine. He is one of the country’s most experienced AERD super-specialists with over 30 years of expertise in managing this challenging condition. He was one of the first Allergy/Immunology fellows to learn the techniques of aspirin desensitization and has subsequently successfully desensitized over 1,000 AERD patients in his career.
In addition to his practice, he has published extensively on the topic. His current research focuses on potential causes, molecular mechanisms and treatments of AERD. He has spoken at national otorhinolaryngology and allergy/immunology meetings and served on AERD expert panels. In addition, he is a proud supporter of the Samter’s Society, a support group for AERD sufferers. Dr. Bosso is a fellow of the American Academy of Allergy (FAAAAI), Asthma and Immunology, American College of Allergy, Asthma and Immunology (FACAAI) and College of Physicians of Philadelphia (FCPP).
My education and training
- Medical School: State University of New York at Buffalo
- Residency: Staten Island University Hospital (North Site)
- Fellowship: Scripps Green Hospital
Spoken languages
English
English
Reviews
678 reviews
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Insurance accepted
Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.
- Aetna Advantra Cares D-SNP
- Aetna Advantra Credit Value
- Aetna Advantra Eagle HMO
- Aetna Advantra Eagle POS
- Aetna Advantra Premier Plus PPO
- Aetna Advantra Value
- Aetna Advantra Value Plus
- Aetna APCN Plus (Multi-Tier)
- Aetna Better Health Kids (CHIP) - DH Only
- Aetna Flexible Five
- Aetna Freedom Core
- Aetna Gold
- Aetna HMO
- Aetna Philly Prime
- Aetna POS
- Aetna PPO APCN
- Aetna Premier
- Aetna Premier Plus
- Aetna Savings Plus
- Aetna Signature Administrators
- Aetna Student Health Plan PPO
- Aetna Upfront Advantage
- First Health HMO
- First Health POS
- First Health PPO
- Meritain - Aramark (Other)
- Meritain - Aramark (Pennsylvania Premier Medical Plan)
- Centivo EPO
- Cigna Healthcare EPO
- Cigna Healthcare HMO
- Cigna Healthcare POS
- Cigna Healthcare PPO
- Claim Watcher (Homestead/ INDECs) Open Access
- Clover Health Choice
- Clover Health Choice Value PPO
- Clover Health Classic HMO
- Clover Health Value
- Devoted Health Choice Giveback Pennsylvania (PPO)
- Devoted Health Choice Pennsylvania (PPO)
- Devoted Health Choice Plus Pennsylvania (PPO)
- Devoted Health Core Pennsylvania (HMO)
- Devoted Health Dual Plus Pennsylvania (HMO D-SNP)
- Devoted Health Giveback Pennsylvania (HMO)
Locations
Penn Medicine hospital privileges
- Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Qualifications and experience
- Allergy and Immunology, 1991
- Internal Medicine, 1988
- American Academy of Allergy, Asthma & Immunology, National
- American College of Allergy, Asthma, and Immunology, National
- American Rhinology Society, National
- The College of Physicians of Philadelphia, Local
- Penn Aspirin Exacerbated Respiratory Disease (AERD) Center
- Recognized annually in Philadelphia Magazine's Top Docs issue from 2018 through 2025
Treatments and conditions
Research
Publications
Herpin LP, Bach R, Bruneto R, Faltas KA, Kohanski MA, Palmer JN, Adappa ND, Douglas JE, Bosso JV. Dupilumab-Related Adverse Events and Intolerance in Aspirin-Exacerbated Respiratory Disease Patients. , Int Forum Allergy Rhinol: 2026
Herpin LP, Finuoli AM, Workman AD, Tang SH, Kuppusamy K, Kohanski MA, Palmer JN, Adappa ND, Douglas JE, Bosso JV. Factors influencing aspirin therapy after desensitization (ATAD) tolerance in aspirin-exacerbated respiratory disease (AERD) patients. , Ann Allergy Asthma Immunol: 2026,288-294
Yu AJ, Phung C, Kuppusamy K, Finuoli AM, Espinosa MC, Douglas JE, Kohanski MA, Adappa ND, Cohen NA, Bosso JV, Palmer JN, Workman AD The Completeness of Surgery Index Predicts Success in CRSwNP With Asthma by SNOT-22 and Asthma Control Test , Int Forum Allergy Rhinol : 2025
Herpin LP, Finuoli AM, Workman AD, Tang SH, Kuppusamy K, Kohanski MA, Palmer JN, Adappa ND, Douglas JE, Bosso JV Factors Influencing Aspirin Therapy after Desensitization (ATAD) Tolerance in Aspirin-Exacerbated Respiratory Disease (AERD) Patients , Ann Allergy Asthma Immunol, 1206(25): 2025,01222-0
Douglas JE, Tang SH, Mani A, Palmer JN, Adappa ND, Kohanski MA, Bosso JV Institutional Experience in Aspirin-Exacerbated Respiratory Disease Yields Favorable Pulmonary and Sinonasal Outcomes , Ear Nose Throat J: 2025
Sell EA, Tan LH, Renner DM, Douglas J, Lee RJ, Kohanski MA, Bosso JV, Kennedy DW, Palmer JN, Adappa ND, Weiss SR, Cohen NA Common Cold Coronavirus 229E Induces Higher Interferon Stimulating Gene Responses in Human Nasal Epithelial Cells from Patients with Chronic Rhinosinusitis with Polyposis , Am J Rhinol Allergy, 39(1): 2025,13-20
Asthana S, Workman AD, Lerner DK, Randell RM, Lopez DF, Kohanski MA, Palmer JN, Adappa ND, Douglas JE, Bosso JV Social factors associated with aspirin desensitization and diagnosis age in aspirin-exacerbated respiratory disease , Int Forum Allergy Rhinol, 15(1): 2025,89-92
Workman AD, Kuppusamy K, Lerner DK, Bosso JV, Douglas JE, Kohanski MA, Adappa ND, Palmer JN Assessing adequacy of surgical extent in CRSwNP: The Completion of Surgery Index , Int Forum Allergy Rhinol, 15(1): 2025,9-17
Jessica Migala The Little-Known Side Effect of Aspirin Asthma Sufferers Need to Know About , AARP Health Online: 2024
Workman Ad, Chang J, Lerner DK, Wilensky J, Montone KT, Bosso JV, Palmer JN, Adappa ND, Kohanski MA Utilizing Histopathology to Predict Success with Macrolide Therapy in CRS Patients , Laryngoscope, 134(3): 2024,1003-1004