Find a Doctor or Practice Location

You can also search for providers and practices at Penn Medicine Lancaster General Health or Princeton Health.

I am searching for a
Reset Form
John V. Bosso, MD

John V. Bosso, MD Physician

Director, Otorhinolaryngology Allergy Clinic Medical Director, Penn AERD Center Clinical Associate Professor of Otorhinolaryngology: Head and Neck Surgery

Dr. Bosso is employed by Penn Medicine.

About Dr. John V. Bosso

John V Bosso, MD, Clinical Associate Professor, serves as Medical Director of the Aspirin Exacerbated Respiratory Disease ( AERD or Samter’s triad) Center and Director of the OTO-Allergy Clinic at Penn Medicine. He is one of the country’s most experienced AERD super-specialists with over 30 years of expertise in managing this challenging condition. He was one of the first Allergy/Immunology fellows to learn the techniques of aspirin desensitization and has subsequently successfully desensitized over 1000 AERD patients in his career.

In addition to his practice , he has published several articles on the topic. His current research focuses on potential causes, molecular mechanisms and treatments of AERD. He has spoken at national otorhinolaryngology meetings and served on AERD expert panels. In addition, he is a proud supporter of the Samter’s Society, a support group for AERD sufferers. Dr. Bosso is a fellow of both the American Academy of Allergy , Asthma and Immunology and the American College of Allergy, Asthma and Immunology.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Otorhinolaryngology

Programs & Centers:

Board Certification:

  • Allergy and Immunology, 1991
  • Internal Medicine, 1988

Clinical Expertise:

  • Allergic Fungal Sinusitis
  • Allergic Rhinitis
  • Allergic Rhinosinusitis
  • Allergies
  • Anterior Nasal Drip
  • Aspirin Exacerbated Respiratory Disease
  • Chronic Rhinosinusitis
  • Chronic Sinus Infection
  • Cough
  • Nasal Congestion
  • Nasal Drainage
  • Nasal Dryness
  • Nasal Obstruction
  • Nasal Polyps
  • Post-Nasal Drip
  • Rhinitis
  • Rhinorrhea
  • Sinonasal Mucocele
  • Sinus Disorders
  • Sinus Infections (Sinusitis)
  • Sinus Polyp
  • Sinus Pressure
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: State University of New York at Buffalo
Residency: Staten Island University Hospital (North Site)
Fellowship: Scripps Green Hospital


American Academy of Allergy, Asthma & Immunology, National American College of Allergy, Asthma, and Immunology, National American Rhinology Society, National Pennsylvania Allergy Asthma and Immunology Society, Local

Hospital Affiliation

Dr. Bosso is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

AERD/Samter's Triad
Chronic Rhinosinusitis
Nasal polyps
Aspirin/NSAID Allergy
Aspirin Desensitization
Biologicals for Asthma, CRS, Nasal Polyps

Selected Publications:

Bachert C, Han JK, Desrosiers M, Hellings PW, Amin N, Lee SE, Mullol J, Greos LS, Bosso JV, Laidlaw TM, Cervin AU, Maspero JF, Hopkins C, Olze H, Canonica GW, Paggiaro P, Cho SH, Fokkens WJ, Fujieda S, Zhang M, Lu X, Fan C, Draikiwicz S, Kamat SA, Khan A, Pirozzi G, Patel N, Graham NMH, Ruddy M, Staudinger H, Weinreich D, Stahl N, Yancopoulos GD, Mannent LP: Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials Lancet 19 (31881-1): 2019.

Patel NN, Triantafillou V, Maina IW, Workman AD, Tong CCL, Kuan EC, Pappagiannoupolis P, Bosso JV, Adappa ND, Palmer JN, Kohanski MA, Herbert DR, Cohen NA: Fungal extracts stimulate solitary chemosensory cell expansion in noninvasive fungal rhinosinusitis Int Forum Allergy Rhinol 9 (7): 730-7,2019.

Kuan EC, Kovacs AJ, Workman AD, Bosso JV, Adappa ND: Efficacy of fluticasone exhalation delivery system in the management of chronic rhinosinusitis: what is the evidence? Int Forum Allergy Rhinol 9 (S1): S16-21,2019.

John V Bosso, MD: Editorial for January 2019 issue of AJRA Am J Rhinol Allergy 33 (1): 5-7,2019.

Triantafillou V, Maina IW, Patel N, Tong CCL, Papagiannopoulis P, Kohanski MA, Kennedy DW, Palmer JN, Adappa ND, Cohen G, Bosso JV: In vitro safety of Ketotifen as a topical nasal rinse Int Forum Allergy Rhinol : 2019.

Kennedy W, Kuan EC, Patel N, Kohanski MA, Tong, CCL, Kennedy DW, Palmer JN, Adappa, ND and Bosso JV.: Preoperative Sinonasal Symptom Scores Predict Post-Surgery, Post-Aspirin Desensitization Disease Status in AERD Journal of Allergy and Clinical Immunology Volume 143, Issue 2, (2): Supplement, Page AB61,2019.

Papagiannoupolis P, Palmer JN, Tong CCL, Bosso JV, Adappa ND: CRS precipitated by TNF alpha inhibitors is the phenotype of CRSsNP Int Forum Allergy Rhinol : 2019.

Luskin, K, Bosso JV and Simon RA: Intranasal Ketorolac-Induced Pancreatitis as a Complication of Modified Oral Aspirin Desensitization in a Patient with Aspirin-Exacerbated Respiratory Disease Journal of Allergyand Clinical Immunology in Practice : 2019.

Glicksman JT, Parasher AK, Doghramji L, Brauer D, Waldram J, Walters K, Bulva J, Palmer JN, Adappa ND, White AA, Bosso JV: Alcohol-Induced Respiratory Symptoms Improve After Aspirin Desensitization in Patients with Aspirin-Exacerbated Respiratory Disease Int Forum Aller Rhinol 8 (10): 1093-1097,2018.

Shawn Radcliffe: "Allergic" to Alcohol? There may be a way to treat your symptoms. Health News : 2018.

Academic Contact Info

Hospital of the University of Pennsylvania
Perelman Center for Advanced Medicine
South Pavilion, 3rd Floor
3400 Civic Center Boulevard

Philadelphia, PA 19104
Phone: (215) 360-0372
Patient appointments: 800-789-7366 (PENN)