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John V. Bosso, MD

John V. Bosso, MD Physician

Director, Otorhinolaryngology Allergy Clinic Medical Director, Penn AERD Center Clinical Associate Professor of Otorhinolaryngology: Head and Neck Surgery

Dr. Bosso is employed by Penn Medicine.

About Dr. John V. Bosso

John V. Bosso, MD, Medical Director of the Aspirin Exacerbated Respiratory Disease (AERD) Center, is a graduate of the allergy/immunology fellowship at Scripps Clinic where the aspirin desensitization procedure was initiated and perfected, and was one of the first trainees to learn the technique. After fellowship, Dr. Bosso founded the first Regional AERD program in the New York metropolitan area and is the most experienced AERD expert in the eastern United States, successfully desensitizing over 1,000 AERD patients during his over 25 years in practice.

Recognized by America's Top Doctors for 2017

Recognized in Philadelphia magazine's annual Top Docs issues for 2018 and 2019

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Otorhinolaryngology

Programs & Centers:

Board Certification:

  • Allergy and Immunology, 1991
  • Internal Medicine, 1988

Clinical Expertise:

  • Allergic Rhinitis
  • Allergies
  • Cough
  • Nasal Polyps
  • Sinonasal Mucocele
  • Sinus Disorders
  • Sinus Infections (Sinusitis)

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: State University of New York at Buffalo
Residency: Staten Island University Hospital (North Site)
Fellowship: Scripps Green Hospital


American Academy of Allergy, Asthma & Immunology, National American College of Allergy, Asthma, and Immunology, National American Rhinology Society, National Pennsylvania Allergy Asthma and Immunology Society, Local

Hospital Affiliation

Dr. Bosso is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

AERD/Samter's Triad
Chronic Rhinosinusitis
Nasal polyps
Aspirin/NSAID Allergy
Aspirin Desensitization
Biologicals for Asthma, CRS, Nasal Polyps

Selected Publications:

Kuan E, Kovacs A, Workman A, Bosso JV, Adappa N.: Efficacy of Fluticasone Exhalation Delivery System (EDS-FLU) in the Management of Chronic Rhinosinusitis: What is the Evidence? International Forum of Allergy & Rhinology. 9 : S16-21.,2019.

Patel N, deBroski H, Adappa N, Triantafillou V, Maina I, Workman A, Tong C, Kuan E, Pappagiannoupolis P, Bosso J, Palmer J, Kohanski M, Cohen N: Fungal extracts stimulate solitary chemosensory cell expansion in noninvasive fungal rhinosinusitis International Forum of Allergy & Rhinology 00 : 1-8,2019.

John V Bosso, MD: Editorial for January 2019 issue of AJRA American Journal of Rhinology and Allergy 33 (1): 5-7,2019.

Claus Bachert, Martin Desrosiers, Joachim Mullol, Peter Hellings, Anders Cervin, Lawrence Sher, John V. Bosso, Stella Lee, Jorge F. Maspero, Shigeharu Fujieda, Shoji Matsune, Xin Lu, Chunpeng Fan Steven Draikiwicz Nikhil Amin, Siddhesh Kamat, Asif Khan, Gianluca Pirozzi, Neil M.H, Graham, Marcella Ruddy, Heribert Staudinger, Leda P. Mannent: A randomized, phase 3 study SINUS-52, evaluating the efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyposis Manuscript submitted to Lancet. (Poster abstract for AAAAI meeting 2/2019) : 2019.

Papagiannopoulos, Peter; Devins, Kyle; Tong, Charles; Yver, Christina; Kuhar, Hannah; Patel, Neil; Bosso, John; Kohanski, Michael; Tajudeen, Bobby; Batra, Pete; Cohen, Noam; Kennedy, David; Palmer, James; Montone, Kathleen T.; Adappa, Nithin: CRS precipitated by TNF alpha inhibitors is the phenotype of CRSsNP International Forum of Allergy & Rhinology : 2019.

Glicksman J, Parasher A, Doghramji L, Brauer D, Waldram K, Bulva J, Palmer J, Adappa N, Bosso J: Alcohol-Induced Respiratory Symptoms Improve After Aspirin Desensitization in Patients with Aspirin-Exacerbated Respiratory Disease. International Forum of Allergy and Rhinology 8 (10): 1093-1097,2018.

Shawn Radcliffe: "Allergic" to Alcohol? There may be a way to treat your symptoms. Health News : 2018.

Jared Kaltwasser: Aspirin Desensitization Reduces Alcohol-Related Respiratory Symptoms : 2018.

Emily Rolen: Why your allergies are so bad this spring. Philly Voice : 2018.

Janissa Delzo: Seasonal Allergies Particularly Bad in 2018 Thanks to Pollen Tsunami Teen Vogue : 2018.

Academic Contact Info

Hospital of the University of Pennsylvania
Perelman Center for Advanced Medicine
South Pavilion, 3rd Floor
3400 Civic Center Boulevard

Philadelphia, PA 19104
Phone: (215) 360-0372
Patient appointments: 800-789-7366 (PENN)