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Jeffrey S. Arkles, MD

Jeffrey S. Arkles, MD Physician

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Arkles is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Cardiology

Programs & Centers:

Board Certification:

  • Cardiovascular Disease, 2013
  • Clinical Cardiac Electrophysiology, 2014
  • Internal Medicine, 2010

Clinical Expertise:

  • Arrhythmia
  • Arrhythmia Device Lead Extraction
  • Atrial Fibrillation (Afib)
  • Atrial Fibrillation Ablation
  • Cardiac Arrest
  • Imaging of Pacemakers and Implantable Cardioverter Defibrillators (ICDs)
  • Implantable Cardiac Devices
  • Implantable Cardioverter Defibrillator
  • Pacemaker
  • Sick Sinus Syndrome
  • Supraventricular Tachycardia (SVT)
  • Ventricular Tachycardia
  • Wolff-Parkinson-White Syndrome

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Jefferson Medical College
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American College of Cardiology, National Heart Rhythm Society, National

Hospital Affiliation

Dr. Arkles is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Translation methods in cardiology.

Selected Publications:

Rodell CB, Lee ME, Wang H, Takebayashi S, Takayama T, Kawamura T, Arkles JS, Dusaj NN, Dorsey SM, Witschey WR, Pilla JJ, Gorman JH 3rd, Wenk JF, Burdick JA, Gorman RC, PMID: 27729419: Injectable Shear-Thinning Hydrogels for Minimally Invasive Delivery to Infarcted Myocardium to Limit Left Ventricular Remodeling. Circ Cardiovasc Interv 9 (10): 1-12,2016.

Seki M, LaCanna R, Powers JC, Vrakas C, Liu F, Berretta R, Chacko G, Holten J, Jadiya P, Wang T, Arkles JS, Copper JM, Houser SR, Huang J, Patel VV, Recchia FA: Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation. J Pharmacol Exp Ther 358 (3): 441-9,2016.

Arkles J, Cooper J: The Emerging Roles of Leadless Devices. Curr Treat Options Cardiovasc Med 18 (2): 14,2016.

Arkles, J.S., Callans, D.J: How to Strategize the “Redo” Ablation Procedure. Practical Guide to Catheter Ablation of Atrial Fibrillation, 2nd edition. (Chapter 25): 343-350,2016.

Peters A, Al Maluli H, Nayeemuddin M, Mirza A, Modi D, Arkles J, Bashir R: Thrombotic thrombocytopenia purpura: a potentially reversible cause of complete heart block. Am J Med 128 (10): e1-3,2015.

Arkles J, Zado E, Supple G, Frankel DS, Callans D, Marchlinski F, Dixit S: Feasibility of Transseptal Access in Patients With Previously Scarred or Repaired Interatrial Septum. J Cardiovasc Electrophysiol 26 (9): 963–968,2015.

Maeda S, Chik WW, Han Y, Liang JJ, Squara F, Arkles JS, Sadek MM, Santangeli P, Frankel DS, Zado ES, Takebayashi S, Dixit S, Callans DJ, Marchlinski FE, Lin D: Effects of Age-Related Aortic Root Anatomic Changes on Left Ventricular Outflow Tract Pace-Mapping Morphologies: A Cardiac Magnetic Resonance Imaging Validation Study. J Cardiovasc Electrophysiol 26 (9): 994–999,2015.

Han QJ, Witschey WR, Fang-Yen CM, Arkles JS, Barker AJ, Forfia PR, Han Y: Altered Right Ventricular Kinetic Energy Work Density and Viscous Energy Dissipation in Patients with Pulmonary Arterial Hypertension: A Pilot Study Using 4D Flow MRI. PLoS One 10 (9): e0138365,2015.

Pierce, M, Bove F, Arkles, J: Race Specific Differences in Atrial Arrhythmias. Scientific Session ACC San Diego, CA : 2015.

Han, Qiao; Witschey, Walter R.; Arkles, Jeffrey; Barker, Alex J.; Han, Yuchi: RV Work Efficiency is Greatly Reduced in Patients with Pulmonary Arterial Hypertension as Evidenced by 4D Flow Cardiac MRI. Society of Cardiac MRI, New Orleans : 2014.

Academic Contact Info

Hospital of the University of Pennsylvania
Cardiovascular Medicine Division
9 Founders Pavilion
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 662-6392
Patient appointments: 800-789-7366 (PENN)