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Jason Stoller, MD

Jason Stoller, MD Non-Penn Medicine Provider

Associate Professor of Clinical Pediatrics

Dr. Stoller is employed by the Children's Hospital of Philadelphia.

Clinical Specialties

Specialty:

  • Pediatrics
    • Neonatology and Newborn Services

Programs & Centers:

Board Certification:

  • Neonatal-Perinatal Medicine, 2008
  • Pediatrics, 2002

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Brown University, Rhode Island Hospital
Fellowship: Children's Hospital of Philadelphia

Memberships

American Academy of Pediatrics – Section on Perinatal Pediatrics, National American Academy of Pediatrics, National American Academy of Pediatrics, Pennsylvania Chapter, Local Developmental Cardiology Group, Children’s Hospital of Philadelphia, Local Eastern Society for Pediatric Research, Local Eastern Society for Pediatric Research, Local Eastern Society for Pediatric Research, Local Philadelphia Perinatal Society, Local Society for Pediatric Research, International Society for Pediatric Research, International Society for Pediatric Research, International Society for Pediatric Research, International

Hospital Affiliation

Dr. Stoller is employed by the Children's Hospital of Philadelphia.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

I am a neonatologist with a research interest in the genetic basis of cardiac development and the molecular mechanisms of congenital heart disease. One of my research projects focuses on understanding DiGeorge syndrome, a relatively common syndrome affecting newborns. Patients with DiGeorge syndrome can have a wide variety of problems including deformities of the head and face, speech problems due to improper separation of the oral and nasal cavities, cleft palate, absence or incomplete development of the thymus and parathyroid glands, and problems with the aortic arch and outflow tract of the heart. The cardiac defects associated with the syndrome, often severe, are present in 75 percent of patients and contribute significantly to morbidity.

Most patients with DiGeorge syndrome carry a large genomic deletion of chromosome 22q11. One gene within this commonly deleted region is the transcription factor, TBX1. My colleagues and I identified the molecular mechanism by which a human TBX1 mutation results in DiGeorge syndrome. Additionally, through work with embryonic stem cells, we identified a new Tbx1 interacting protein that is critical for the earliest stages of embryonic development and may be important in understanding the function of Tbx1. Understanding the mechanisms of Tbx1 function will provide insight into both normal and abnormal cardiac development.

A second research project is to identify genes that are critical for differentiating the left sixth aortic arch artery into the ductus arteriosus. Patent ductus arteriosus, a condition in which a child’s ductus arteriosus does not close after birth, is major cause of neonatal morbidity and therapeutic options are limited. A better understanding of what differentiates the left sixth aortic arch artery from the other aortic arch arteries during development will elucidate potential targets for future pharmacologic treatment strategies and has the potential to improve long-term outcomes among extremely low birthweight neonates. Tools used for this project include RNA transcript microarrays and in vivo disease models.

Selected Publications:

Huayan Zhang, Kathleen Nilan, Kevin Dysart, William Fox, Erik Jensen, Kathryn Maschhoff, David Munson, Jason Stoller, Haresh Kirpalani: Caring for Infants with Severe Chronic Lung Disease (CLD) - Five Year Experience of a Multidisciplinary Care Program AAP National Conference : 2016.

Erin K. Tkach, Jean Carroll, Christine Correale, Kevin Dysart, Michael Padula, David Munson, Jason Stoller, Maria Fraga, Lisa Tyler, Patricia Clifford, John Chuo: Reducing inhaled nitric oxide used in persistent pulmonary hypertension of the newborn Quality and Patient Safety Day 2016. The Children's Hospital of Philadelphia : 2016.

Erin K. Tkach, Jean Carroll, Christine Correale, Kevin Dysart, Michael Padula, David Munson, Jason Stoller, Maria Fraga, Lisa Tyler, Patricia Clifford, John Chuo: Reducing inhaled nitric oxide used in persistent pulmonary hypertension of the newborn AAP National Conference : 2016.

John Chuo, Jean Marie Carroll, Theresa O'Connor, Heather French, Jason Stoller, Danielle McCormack, Natalie Rintoul: Safe Transitions and Euthermia in the Perioperative Period in Infants and Neonates Children's Hospital Neonatal Consortium Annual Meeting : 2015.

Rintoul N, Chuo J, French H, Stoller JZ, O'Connor T, McCormack D, Carroll JM: Safe Transitions and Euthermia in the Perioperative Period in Infants and Neonates Quality and Patient Safety Day 2015. The Children's Hospital of Philadelphia : 2015.

Napolitano N, Stoller JZ: PPHN: New Evidence-Based Approaches eNeonatal Review Newsletter 10 (9): 2015.

Christ L, Barber J, Murray A, Dunleavy M, Stoller JZ, Taha D, Brown-Jackson L, McElroy M, Posencheg M.: Reducing Intraventricular Hemorrhage in a Level III Neonatal Intensive Care Unit. BMJ Quality & Safety. 21st Annual Institute for Healthcare Improvement Scientific Symposium on Improving the Quality and Value of Health Care. 24 (11): 731,2015.

Napolitano, N and Stoller JZ: PPHN: New Evidence-based Approaches (Podcast) eNeonatal Reviews Newsletter 10 (10): 2015.

Subbaraj I, Pan H, Zhang T, Stoller JZ: The Role of Jun in Aortic Arch Artery Formation and Remodeling (Platform Presentation) Eastern Society for Pediatric Research : 2014.

Shelton E, Ector G, Galindo C, Hooper C, Brown N, Wilkerson I, Pfaltzgraff E, Paria B, Cotton R, Stoller JZ, Reese J.: Transcriptional profiling reveals ductus arteriosus-specific genes that regulate vascular tone. Physiological Genomics. 46 (13): 457-66,2014.

View all publications

Academic Contact Info

34th Street and Civic Center Blvd
Main Building, 2nd Floor Northwest

Philadelphia, PA 19104
Patient appointments: 800-789-PENN (7366)