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Jason D. Christie, MD, MS

Jason D. Christie, MD, MS Physician

Chief, Pulmonary, Allergy and Critical Care Division Robert M. Kotloff/Nancy P. Blumenthal Professor for Advanced Lung Disease Professor of Epidemiology in Biostatistics and Epidemiology

Dr. Christie is employed by Penn Medicine.

About Dr. Jason D. Christie

Recognized by America's Top Doctors, 2012 - 2018

Recognized in Philadelphia magazine's annual Top Docs issues from 2010 to 2019

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Pulmonary Medicine

Programs & Centers:

Board Certification:

  • Critical Care Medicine, 2000
  • Pulmonary Disease, 1999

Clinical Expertise:

  • Acute Respiratory Distress Syndrome (ARDS)
  • Bilevel Positive Airway Pressure
  • Cardiogenic Shock
  • Cardiovascular Critical Care
  • Continuous Positive Airway Pressure (CPAP)
  • Hyperglycemic Hyperosmolar Syndrome
  • Hypertensive Crisis
  • Hypotension
  • Hypovolemia
  • Hypovolemic Shock
  • Lung Transplantation
  • Mechanical Ventilation
  • Multiple Organ Failure
  • Respiratory Failure
  • Sepsis (Septicemia)
  • Septic Shock
  • Status Asthmaticus
  • Therapeutic Hypothermia
  • Uncontrolled Bleeding
  • Ventilator Dependent
  • Ventilator Management
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Columbia University
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American Board of Internal Medicine, National American College of Chest Physicians, National American College of Epidemiology, National American College of Physicians, National American Society of Transplantation, National American Thoracic Society, National Board of Directors: The ARDS Foundation (, National Drinker Critical Care Society, Local International Society of Heart and Lung Transplantation Fellowship, International International Society of Heart and Lung Transplantation, International Laennec Society, Local NHLBI HLBP (M1) P01 Study Section, National NHLBI Mentored Patient-Oriented Research Review Committee, National NHLBI PETAL Network, National NHLBI Science Moving Towards Research Translation and Therapy (SMARTT) program, National Pennsylvania Thoracic Society, Local Society for Epidemiologic Research, International Society of Critical Care Medicine, International

Hospital Affiliation

Dr. Christie is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Dr. Christie's career is focused on translational research studies of the risks, pathogenesis, treatment, and outcomes of acute lung injury in the transplant and non-transplant human populations. His research integrates new knowledge generated from bench studies with epidemiology approaches in well-phenotyped, large human populations to generate new definitions of human syndromes, improved diagnostics and prognostics, and targeted therapy approaches in advanced lung diseases and critical illness.

Dr. Christie is the founder of the lung transplant outcomes group (LTOG), which is a multicentered cohort study the etiology and pathogenesis of acute lung injury following lung transplantation (termed primary graft dysfunction). Active LTOG research themes focus on the mechanisms of clinical factors that elevate PGD risk, including donor smoke exposure, recipient obesity and body composition, pulmonary hypertension, alterations in lung microbiome, and autoimmunity to lung collagens. His multidisciplinary lung transplant research focuses on genetics, innate immunity, regulatory T-cells, innate lymphoid cell (ILC) populations in the lung, ischemia reperfusion injury, inflammation, and autoimmunity.

Selected Publications:

Jones TK1, Feng R2, Kerchberger VE3, Reilly JP4, Anderson BJ5, Shashaty MGS6, Wang F7, Dunn TG4, Riley TR8, Abbott J9, Ittner CAG10, Christiani DC11, 12, Mikacenic C13, Wurfel MM14, Ware LB15, Calfee CS16, Matthay MA17, Christie JD18, Meyer NJ19.: Plasma sRAGE Acts as Genetically Regulated Causal Intermediate in Sepsis-Associated ARDS American Journal of respiratory and critical care medicine : 2019.

Miano TA1, 2, 3, Flesch JD4, Feng R2, 3, Forker CM4, Brown M4, Oyster M4, Kalman L4, Rushefski M4, Cantu E 3rd5, Porteus M4, Yang W1, 2, 3, Russel Localio Jd A2, 3, Diamond JM4, Christie JD2, 3, 4, Shashaty MGS2, 4.: Early Tacrolimus Concentrations After Lung Transplant are Predicted by Combined Clinical and Genetic Factors and Associated with Acute Kidney Injury. Clinical Pharmacology and Therapeutics : 2019.

Anderson MR1, Udupa JK2, Edwin E3, Diamond JM4, Singer JP5, Kukreja J6, Hays SR5, Greenland JR5, Ferrante A3, Lippel M1, Blue T1, McBurnie A1, Oyster M4, Kalman L4, Rushefski M4, Wu C2, Pednekar G2, Liu W1, Arcasoy S1, Sonett J7, D'Ovidio F7, Bacchetta M8, Newell JD9, Torigian D2, Cantu E10, Farber DL11, Giles JT1, Tong Y2, Palmer S12, Ware LB13, Hancock WW14, Christie JD4, Lederer DJ: Adipose tissue quantification and primary graft dysfunction after lung transplantation: The Lung Transplant Body Composition study. The journal of heart and lung transplantation : [Epub ahead of print],2019.

Sivakumar P1, Thompson JR2, Ammar R2, Porteous M3, McCoubrey C3, Cantu E 3rd4, Ravi K5, Zhang Y5, Luo Y6, Streltsov D1, Beers MF3, 7, Jarai G1, Christie JD3: RNA sequencing of transplant-stage idiopathic pulmonary fibrosis lung reveals unique pathway regulation. ERJ open research : 2019.

Anderson MR1, Edwin EA1, Diamond JM2, Ferrante A Jr1, Sonett J1, D'Ovidio F1, Arcasoy S1, Cantu E 3rd2, Christie JD2, Lederer DJ1.: Aryl-Hydrocarbon Receptor Repressor Gene in Primary Graft Dysfunction after Lung Transplantation. American journal of respiratory cell and molecular biology : 268-271,2019.

Monticelli LA1, Diamond JM2, Saenz SA3, Tait Wojno ED4, Porteous MK5, Cantu E6, Artis D7, Christie JD8.: Lung Innate Lymphoid Cell Composition is Altered in Primary Graft Dysfunction. American journal of respiratory and critical care medicine : [Epub ahead of print],2019.

Simon-Soro A1, Sohn MB2, McGinniss JE1, Imai I3, Brown MC1, Knecht VR1, Bailey A4, Clarke EL5, Cantu E6, Li H2, Bittinger K7, Diamond JM8, Christie JD1, Bushman FD9, Collman RG10.: Upper Respiratory Dysbiosis with a Facultative-Dominated Ecotype in Advanced Lung Disease and Dynamic Change after Lung Transplant. Annals of the American Thoracic Society : 2019.

Shashaty MGS1, 2, Forker CM1, Miano TA2, Wu Q2, Yang W2, Oyster ML1, Porteous MK1, Cantu EE 3rd3, Diamond JM1, Christie JD: The association of post-lung transplant acute kidney injury with mortality is independent of primary graft dysfunction: A cohort study. Clinical Transplantation : 2019.

Anderson MR1, Kolaitis NA2, Gao Y2, Kukreja J2, Greenland J2, Hays S2, Wolters P2, Golden J2, Diamond J3, Palmer S4, Arcasoy S1, Udupa J5, Christie JD3, Lederer DJ1, 6, Singer JP2.: A nonlinear relationship between visceral adipose tissue and frailty in adult lung transplant candidates. American Journal of Transplantation : 2019.

Zaffiri L1, Shah RJ2, Stearman RS3, Rothhaar K3, Emtiazjoo AM4, Yoshimoto M3, Fisher AJ3, Mickler EA3, Gartenhaus MD3, Cohort LTOG5, Diamond JM6, Geraci MW3, Christie JD6, Wilkes DS7.: Collagen type-V is a danger signal associated with primary graft dysfunction in lung transplantation. Transplant Immunology : 101224,2019.

View all publications

Academic Contact Info

Division of Pulmonary and Critical Care Medicine
Hospital of the University of Pennsylvania
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania School of Medicine
423 Guardian Drive
221 Blockley Hall

Philadelphia, PA 19104
Phone: (215) 573-3209
Patient appointments: 800-789-7366 (PENN)

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