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Jason D. Christie, MD, MS

Jason D. Christie, MD, MS Physician

Chief, Pulmonary, Allergy and Critical Care Division Professor of Epidemiology in Biostatistics and Epidemiology Robert M. Kotloff/Nancy Blumenthal Professor for Advanced Lung Disease

Dr. Christie is employed by Penn Medicine.

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About Dr. Jason D. Christie

Recognized in Philadelphia magazine's annual Top Docs issue from 2010 through 2017

Recognized by America's Top Doctors, 2012-14

Clinical Specialties


  • Pulmonary Medicine

Programs & Centers:

Board Certification:

  • Critical Care Medicine, 2000
  • Pulmonary Disease, 1999

Clinical Expertise:

  • Critical Care Medicine
  • Lung Disease
  • Lung Injury

Practice Locations and Appointments

  • Harron Lung Center

    Perelman Center for Advanced Medicine West Pavilion, 1st Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-7366 (PENN)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Columbia University
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American Board of Internal Medicine, National American College of Chest Physicians, National American College of Epidemiology, National American College of Physicians, National American Society of Transplantation, National American Thoracic Society, National Board of Directors: The ARDS Foundation (, National Center of Biologics Evaluation and Research, FDA, National Cystic Fibrosis Foundation, National Department of Defense, National Department of Defense, National Drinker Critical Care Society, Local Federal Drug Administration, National International Society of Heart and Lung Transplantation (ISHLT) Working Group on Primary Graft Dysfunction , International International Society of Heart and Lung Transplantation (ISHLT) Working Group on Primary Graft Dysfunction, International International Society of Heart and Lung Transplantation Fellowship , International International Society of Heart and Lung Transplantation, 25 year Society Strategic Planning Committee , International International Society of Heart and Lung Transplantation, International Laennec Society, Local Medical Advisory Board: Acute Respiratory Distress Syndrome ARDS Support Center ( , National National Institute of Health (NIH) Clinical Trials in Organ Transplantation (CTOT) Steering Committee member , National National Institutes of Health, National NHLBI ARDSnet Natural History Committee , National NHLBI ARDSnet Steering Committee Investigator, National NHLBI PETAL Network , National NHLBI Science Moving Towards Research Translation and Therapy (SMARTT) program, National NHLBI Special Emphasis Panel 2012/01 ZHL1 CSR-X (F2), National NHLBI UM1 Phase II Clinical Trials of Novel Therapies for Lung Diseases Review (RFA-HL-12-022), National NHLBI Workshop: Building Partnerships Towards a Global Approach to Genetics of Asthma and Other Lung Diseases, National NIH Director’s Research Opportunity (RC4) Study Section (ZRG1 VH-D (55) R), National NIH Genes to Function Study Section (NIH-CSR-PA11-011), National NIH Lung Cellular, Molecular, and Immunobiology Study Section (LCMI) , National NIH Lung Injury, Repair, and Remodeling Study Section (LIRR), National NIH NHLBI K02/K08 Study Section, (PA-06-512 and PA-06-527) , National NIH NIGMS Scientific Review Committee, Special Emphasis Panel to Review P50 "Trauma and Burn Research Centers" , National NIH NIGMS Scientific Review Committee, Special Emphasis Panel to Review RFP (ZGM1 TB-5 (3P)) , National Pennsylvania Thoracic Society , Local Research Foundation - Flanders, International Research Foundation - Flanders, International Society for Epidemiologic Research, International Society of Critical Care Medicine, International Special Emphasis Panel/Scientific Review Group 2009/10 HLBP - Research Program Project Workgroup 34, National United Kingdom Medical Research Council, International UNOS(United Network for Organ Sharing)/ISHLT (International Society of Heart and Lung Transplantation) Thoracic Transplant Registry, International

Hospital Affiliation

Dr. Christie is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Dr. Christie's career is focused on translational research studies of the risks, pathogenesis, treatment, and outcomes of acute lung injury in the transplant and non-transplant human populations. His research integrates new knowledge generated from bench studies with epidemiology approaches in well-phenotyped, large human populations to generate new definitions of human syndromes, improved diagnostics and prognostics, and targeted therapy approaches in advanced lung diseases and critical illness.

Dr. Christie is the founder of the lung transplant outcomes group (LTOG), which is a multicentered cohort study the etiology and pathogenesis of acute lung injury following lung transplantation (termed primary graft dysfunction). Active LTOG research themes focus on the mechanisms of clinical factors that elevate PGD risk, including donor smoke exposure, recipient obesity and body composition, pulmonary hypertension, alterations in lung microbiome, and autoimmunity to lung collagens. His multidisciplinary lung transplant research focuses on genetics, innate immunity, regulatory T-cells, innate lymphoid cell (ILC) populations in the lung, ischemia reperfusion injury, inflammation, and autoimmunity.

Selected Publications:

Panzer Ariane R, Lynch Susan V, Langelier Chaz, Christie Jason D, McCauley Kathryn, Nelson Mary, Cheung Christopher K, Benowitz Neal L, Cohen Mitchell J: Lung Microbiota is Related to Smoking Status and to Development of ARDS in Critically Ill Trauma Patients. American journal of respiratory and critical care medicine : 2017.

Snell Gregory I, Yusen Roger D, Weill David, Strueber Martin, Garrity Edward, Reed Anna, Pelaez Andres, Whelan Timothy P, Perch Michael, Bag Remzi, Budev Marie, Corris Paul A, Crespo Maria M, Witt Chad, Cantu Edward: Report of the ISHLT Working Group on Primary Lung Graft Dysfunction, part I: Definition and grading-A 2016 Consensus Group statement of the International Society for Heart and Lung Transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 36 (10): 1097-1103,2017.

Meyer Nuala J, Reilly John P, Anderson Brian J, Palakshappa Jessica A, Jones Tiffanie K, Dunn Thomas G, Shashaty Michael G S, Feng Rui, Christie Jason D: Mortality Benefit of Recombinant Human Interleukin-1 Receptor Antagonist for Sepsis Varies by Initial Interleukin-1 Receptor Antagonist Plasma Concentration. Critical care medicine : 2017.

Khan Akram, Benthin Cody, Zeno Brian, Albertson Timothy E, Boyd John, Christie Jason D, Hall Richard, Poirier Germain, Ronco Juan J, Tidswell Mark, Hardes Kelly, Powley William M, Wright Tracey J, Siederer Sarah K, Fairman David A, Lipson David A, Bayliffe Andrew I: A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome. Critical care (London, England) 21 (1): 234,2017.

Cantu Edward, Diamond Joshua M, Suzuki Yoshikazu, Lasky Jared, Schaufler Christian, Lim Brian, Shah Rupal, Porteous Mary, Lederer David J, Kawut Steven M, Palmer Scott M, Snyder Laurie D, Hartwig Matthew G, Lama Vibha N, Bhorade Sangeeta, Bermudez Christian, Crespo Maria, McDyer John, Wille Keith, Orens Jonathan, Shah Pali D, Weinacker Ann, Weill David, Wilkes David, Roe David, Hage Chadi, Ware Lorraine B, Bellamy Scarlett L: Quantitative Evidence for Revising the Definition of Primary Graft Dysfunction After Lung Transplant. American journal of respiratory and critical care medicine : 2017.

Miano Todd A, Cuker Adam, Christie Jason D, Martin Niels, Smith Brian, Makley Amy T, Guo Wensheng: Comparative Effectiveness of Enoxaparin vs Dalteparin for Thromboprophylaxis After Traumatic Injury. Chest : 2017.

Winterbottom Christopher J, Shah Rupal J, Patterson Karen C, Kreider Maryl E, Panettieri Reynold A, Rivera-Lebron Belinda, Miller Wallace T, Litzky Leslie A, Penning Trevor M, Heinlen Krista, Jackson Tara, Localio A Russell: Exposure to Ambient Particulate Matter Is Associated With Accelerated Functional Decline in Idiopathic Pulmonary Fibrosis. Chest : 2017.

Akimova Tatiana, Zhang Tianyi, Negorev Dmitri, Singhal Sunil, Stadanlick Jason, Rao Abhishek, Annunziata Michael, Levine Matthew H, Beier Ulf H, Diamond Joshua M, Christie Jason D, Albelda Steven M, Eruslanov Evgeniy B: Human lung tumor FOXP3+ Tregs upregulate four "Treg-locking" transcription factors. JCI insight 2 (16): 2017.

Porteous Mary K, Lee James C, Lederer David J, Palmer Scott M, Cantu Edward, Shah Rupal J, Bellamy Scarlett L, Lama Vibha N, Bhorade Sangeeta M, Crespo Maria M, McDyer John F, Wille Keith M, Localio A Russell, Orens Jonathan B, Shah Pali D, Weinacker Ann B, Arcasoy Selim, Wilkes David S, Ware Lorraine B, Christie Jason D, Kawut Steven M: Clinical Risk Factors and Prognostic Model for Primary Graft Dysfunction after Lung Transplantation in Patients with Pulmonary Hypertension. Annals of the American Thoracic Society 14 (10): 1514-1522,2017.

Borders CF, Suzuki Y, Lasky J, Schaufler C, Mallem D, Lee J, Carney K, Bellamy SL, Bermudez CA, Localio AR, Christie JD, Diamond JM: Massive Donor Transfusion Potentially Increases Recipient Mortality After Lung Transplantation. Journal of Thoracic Cardiovascular Surgery 153 (5): 1197-1203,2017.

View all publications

Academic Contact Info

Division of Pulmonary and Critical Care Medicine
Hospital of the University of Pennsylvania
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania School of Medicine
423 Guardian Drive
221 Blockley Hall

Philadelphia, PA 19104
Phone: (215) 573-3209
Patient appointments: 800-789-7366 (PENN)

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