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Jason D. Christie, MD, MS

Jason D. Christie, MD, MS Physician

Chief, Pulmonary, Allergy and Critical Care Division Robert M. Kotloff/Nancy Blumenthal Professor for Advanced Lung Disease Professor of Epidemiology in Biostatistics and Epidemiology

Dr. Christie is a Penn Medicine employed physician.

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About Dr. Jason D. Christie

Recognized in Philadelphia magazine's annual Top Docs issue from 2010 through 2017

Recognized by America's Top Doctors, 2012-14

Clinical Specialties


  • Pulmonary Medicine

Programs & Centers:

Board Certification:

  • Critical Care Medicine, 2000
  • Pulmonary Disease, 1999

Clinical Expertise:

  • Critical Care Medicine
  • Lung Disease
  • Lung Injury

Practice Locations and Appointments

  • Harron Lung Center

    Perelman Center for Advanced Medicine West Pavilion, 1st Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-7366 (PENN)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Columbia University
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American Board of Internal Medicine, National American College of Chest Physicians, National American College of Epidemiology, National American College of Physicians, National American Society of Transplantation, National American Thoracic Society, National Board of Directors: The ARDS Foundation (, National Center of Biologics Evaluation and Research, FDA, National Cystic Fibrosis Foundation, National Department of Defense, National Department of Defense, National Drinker Critical Care Society, Local Federal Drug Administration, National International Society of Heart and Lung Transplantation (ISHLT) Working Group on Primary Graft Dysfunction , International International Society of Heart and Lung Transplantation (ISHLT) Working Group on Primary Graft Dysfunction, International International Society of Heart and Lung Transplantation Fellowship , International International Society of Heart and Lung Transplantation, 25 year Society Strategic Planning Committee , International International Society of Heart and Lung Transplantation, International Laennec Society, Local Medical Advisory Board: Acute Respiratory Distress Syndrome ARDS Support Center ( , National National Institute of Health (NIH) Clinical Trials in Organ Transplantation (CTOT) Steering Committee member , National National Institutes of Health, National NHLBI ARDSnet Natural History Committee , National NHLBI ARDSnet Steering Committee Investigator, National NHLBI PETAL Network , National NHLBI Science Moving Towards Research Translation and Therapy (SMARTT) program, National NHLBI Special Emphasis Panel 2012/01 ZHL1 CSR-X (F2), National NHLBI UM1 Phase II Clinical Trials of Novel Therapies for Lung Diseases Review (RFA-HL-12-022), National NHLBI Workshop: Building Partnerships Towards a Global Approach to Genetics of Asthma and Other Lung Diseases, National NIH Director’s Research Opportunity (RC4) Study Section (ZRG1 VH-D (55) R), National NIH Genes to Function Study Section (NIH-CSR-PA11-011), National NIH Lung Cellular, Molecular, and Immunobiology Study Section (LCMI) , National NIH Lung Injury, Repair, and Remodeling Study Section (LIRR), National NIH NHLBI K02/K08 Study Section, (PA-06-512 and PA-06-527) , National NIH NIGMS Scientific Review Committee, Special Emphasis Panel to Review P50 "Trauma and Burn Research Centers" , National NIH NIGMS Scientific Review Committee, Special Emphasis Panel to Review RFP (ZGM1 TB-5 (3P)) , National Pennsylvania Thoracic Society , Local Research Foundation - Flanders, International Research Foundation - Flanders, International Society for Epidemiologic Research, International Society of Critical Care Medicine, International Special Emphasis Panel/Scientific Review Group 2009/10 HLBP - Research Program Project Workgroup 34, National United Kingdom Medical Research Council, International UNOS(United Network for Organ Sharing)/ISHLT (International Society of Heart and Lung Transplantation) Thoracic Transplant Registry, International

Hospital Affiliation

Dr. Christie is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Dr. Christie's career is focused on translational research studies of the risks, pathogenesis, treatment, and outcomes of acute lung injury in the transplant and non-transplant human populations. His research integrates new knowledge generated from bench studies with epidemiology approaches in well-phenotyped, large human populations to generate new definitions of human syndromes, improved diagnostics and prognostics, and targeted therapy approaches in advanced lung diseases and critical illness.

Dr. Christie is the founder of the lung transplant outcomes group (LTOG), which is a multicentered cohort study the etiology and pathogenesis of acute lung injury following lung transplantation (termed primary graft dysfunction). Active LTOG research themes focus on the mechanisms of clinical factors that elevate PGD risk, including donor smoke exposure, recipient obesity and body composition, pulmonary hypertension, alterations in lung microbiome, and autoimmunity to lung collagens. His multidisciplinary lung transplant research focuses on genetics, innate immunity, regulatory T-cells, innate lymphoid cell (ILC) populations in the lung, ischemia reperfusion injury, inflammation, and autoimmunity.

Selected Publications:

Borders CF, Suzuki Y, Lasky J, Schaufler C, Mallem D, Lee J, Carney K, Bellamy SL, Bermudez CA, Localio AR, Christie JD, Diamond JM, Cantu E: Massive Donor Transfusion Potentially Increases Recipient Mortality After Lung Transplantation. Journal of Thoracic Cardiovascular Surgery 153 (5): 1197-1203,2017.

Patterson KC, Shah RJ, Porteous MK, Christie JD, D'Errico C, Chadwick M, Triano M, Deshpande C, Rossman MD, Litzky LA, Kreider ME, Miller WT Jr: Interstitial Lung Disease in the Elderly. Chest 151 (4): 838-844,2017.

Tong Y, Udupa JK, Torigian DA, Odhner D, Wu C, Pednekar G, Palmer S, Rozenshtein A, Shirk MA, Newell JD, Porteous M, Diamond JM, Christie JD, Lederer DJ: Chest Fat Quantification via CT Based on Standardized Anatomy Space in Adult Lung Transplant Candidates. PLoS One 12 (1): e0168932,2017.

Diamond JM, Arcasoy S, McDonnough JA, Sonett JR, Bacchetta M, D'Ovidio F, Cantu E, Bermudez CA, McBurnie A, Rushefski M, Kalman LH, Oyster M, D'Errico C, Suzuki Y, Giles JT, Ferrante A, Lippel M, Singh G, Lederer DJ, Christie JD: Adipose Gene Expression Profile Changes with Lung Allograft Reperfusion. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 17 (1): 239-245,2017.

Diamond JM, Cantu E, Porteous M, Suzuki Y, Meyer KC, Lederer D, Milewski RK, Arcasoy S, D'Ovidio F, Bacchetta M, Sonett JR, Singh G, Costa J, Tobias JW, Rodriguez H, Van Deerlin VM, Olthoff KM, Shaked A, Chang BL, Christie JD: Peripheral Blood Gene Expression Changes Associated with Primary Graft Dysfunction after Lung Transplantation. American Journal of Transplant Epub ahead of Print : 2017.

Anderson BJ, Reilly JP, Shashaty MG, Palakshappa JA, Wysoczanski A, Dunn TG, Kazi A, Tommasini A, Mikkelsen ME, Schweickert WD, Kolson DL, Christie JD, Meyer NJ: Admission Plasma Levels of the Neuronal Injury Marker Neuron-specific Enolase are Associated with Mortality and Delirium in Sepsis. Journal of Critical Care 36 : 18-23,2016.

Podolanczuk AJ, Oelsner EC, Barr RG, Hoffman EA, Armstrong HF, Austin JH, Basner RC, Bartels MN, Christie JD, Enright PL, Gochuico BR, Hinckley Stukovsky K, Kaufman JD, Hrudaya Nath P, Newell JD Jr, Palmer SM, Rabinowitz D, Raghu G, Sell JL, Sieren J, Sonavane SK, Tracy RP, Watts JR, Williams K, Kawut SM, Lederer DJ: High Attenuation Areas on Chest Computed Tomography in Community-dwelling Adults: The MESA Study. European Respiratory Journal 48 (5): 1442-1452,2016.

Bhatraju PK, Mukherjee P, Robinson-Cohen C, O'Keefe GE, Frank AJ, Christie JD, Meyer NJ, Liu KD, Matthay MA, Calfee CS, Christiani DC, Himmelfarb J, Wurfel MM: Acute Kidney Injury Subphenotypes Based on Creatinine Trajectory Identifies Patients at Increased Risk of Death. Critical Care 20 (1): 372,2016.

Abbas A A, Diamond J M, Chehoud C, Chang B, Kotzin J J, Young J C, Imai I, Haas A R, Cantu E, Lederer D J, Meyer K, Milewski R K, Olthoff K M, Shaked A, Christie J D, Bushman F D, Collman R G: The Perioperative Lung Transplant Virome: Torque Teno Viruses are Elevated in Donor Lungs and Show Divergent Dynamics In Primary Graft Dysfunction. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons : [Epub ahead of print],2016.

Patel NB, Christie JD: Alveolar Type 2 Cell Transplantation in IPF: Recreating the Silver Lining. Chest 150 (3): 481-2,2016.

View all publications

Academic Contact Info

Division of Pulmonary and Critical Care Medicine
Hospital of the University of Pennsylvania
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania School of Medicine
423 Guardian Drive
221 Blockley Hall

Philadelphia, PA 19104
Phone: (215) 573-3209
Fax: (215) 573-0198
Patient appointments: 800-789-7366 (PENN)

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