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Janos L. Tanyi, MD, PhD

Janos L. Tanyi, MD, PhD Surgeon

Assistant Professor of Obstetrics and Gynecology at the Hospital of the University of Pennsylvania

Languages spoken:

  • Hungarian

Dr. Tanyi is a Penn Medicine employed physician.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties


  • Gynecologic Oncology

Programs & Centers:

Board Certification:

  • Obstetrics and Gynecology - Gynecologic Oncology, 2014
  • Obstetrics and Gynecology, 2010

Clinical Expertise:

  • Cervical Cancer
  • Cervical Dysplasia
  • Cervical Lesions
  • Cervix Biopsy
  • Chemotherapy for Gynecologic Cancers
  • Colposcopy
  • Endometrial Cancer
  • Fallopian Tube Cancer
  • Gynecologic Cancer
  • Gynecologic Cancer Surgery
  • Gynecologic Surgery
  • Gynecology Clinical Trials
  • Hysterectomy (Uterus Surgery)
  • Hysteroscopy
  • Laparoscopic Supracervical Hysterectomy
  • Laparoscopic Surgery
  • Laparoscopy
  • Loop Electrosurgical Excision Procedure (LEEP)
  • Minimally Invasive Hysterectomy
  • Ovarian Cancer
  • Robotic Surgery
  • Robotic-Assisted Laparoscopic Hysterectomy (RALH)
  • Trophoblastic Cancer
  • Uterine Cancer
  • Vaginal Cancer
  • Vulvar Cancer

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University Medical School of Debrecen
Residency: Semmelweis University, Medical School
Residency: Baylor College of Medicine - Ben Taub General Hospital
Fellowship: Hospital of the University of Pennsylvania


Fellow, American College of Obstetrics and Gynecology, National Inactive member, European Association of Gynecologists and Obstetricians, International

Hospital Affiliation

Dr. Tanyi is a Penn Medicine employed physician.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

George E, Kim H, Krepler C, Wenz B, Makvandi M, Tanyi JL, Brown E, Zhang R, Brafford P, Jean S, Mach RH, Lu Y, Mills GB, Herlyn M, Morgan M, Zhang X, Soslow R, Drapkin R, Johnson N, Zheng Y, Cotsarelis G, Nathanson KL, Simpkins F: A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers. JCI Insight 2(1):e89760 : 2017.

Tanyi JL, Stashwick C, Plesa G, Morgan MA, Porter D, Maus MV, June CH: Possible compartmental cytokine release syndrome in a patient with recurrent ovarian cancer after treatment with Mesothelin-targeted CAR-T cells. J Immunother 40(3):104-10 : 2017.

Santoiemma PP, Reyes C, Wang LP, McLane MW, Feldman MD, Tanyi JL, Powell DJ Jr: Systematic evaluation of multiple immune markers reveals prognostic factors in ovarian cancer. Gynecol Oncol 143(1):120-7 : 2016.

Jean S, Li J, Katsaros D, Wubbenhorst B, Maxwell KN, Fishbein L, McLane MW, Benedetto C, Canuto EM, Mitra N, Zhang L, Nathanson KL, Tanyi JL: Paclitaxel is necessary for improved survival in epithelial ovarian cancers with homologous recombination gene mutations. Oncotarget 7(30):48577-585 : 2016.

Zhang Y, He Q, Hu Z, Feng Y, Fan L, Tang Z, Yuan J, Shan W, Li C, Hu X, Tanyi JL, Fan Y, Huang Q, Montone K, Dang CV, Zhang L: Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer. Nat Struct Mol Biol 23(6):522-30 : 2016.

Coukos G, Tanyi J, Kandalaft LE.: Opportunities in immunotherapy of ovarian cancer. Ann Oncol. : suppl 1):i11-i15,2016.

O’Hara M, Stashwick C, Haas AR, Tanyi JL: Mesothelin as a target for chimeric antigen receptor modified T cells as anticancer therapy. Immunotherapy 8(4):449-60 : 2016.

George E, Kima H, Raglanda R, Brown E, Butlerb L, Giladb O, Tanyi JL, Zhang R, Krepler C, Leed R, Morgan MA, Burger RA, Ko EM, Kim SH, Herlyn M and Simpkins F: Capitalizing on synthetic lethality in homologous recombination-deficient high-grade serous ovarian cancers with a novel ATR inhibitor. Poster on the 47th Annual Meeting of Women’s Cancer, SGO, San Diego, CA, March, : 2016.

Tanyi JL, Haas AR, Beatty GB, Stashwick CJ, O'Hara MH, Morgan MA, Porter DL, Melenhorst JJ, Plesa G, Lacey SF, June CH: Anti-mesothelin chimeric antigen receptor T cells in patients with epithelial ovarian cancer.(suppl; abstr 5511) J Clin Oncol 34 : 2016.

Haas RA, Plesa G, Torigian D, Moon E, O’Hara M, Beatty G, Tanyi JL, Nelson A, Kerr N, Lacey S, Melenhorst J, Albelda SA, June C: Phase I trial of lentiviral CART-meso cells in progressive malignant pleural mesothelioma (MPM). International Mesothelioma Interest Group 2016 Annual Meeting. Birmingham, UK, May : 2016.

Academic Contact Info

University of Pennsylvania Health System,
Department of Obstetrics and Gynecology
Jordan Center for Gynecologic Cancer at Penn
Perelman Center for Advanced Medicine
3400 Civic Center Boulevard, 3 West

Philadelphia, PA 19104
Phone: (215) 662-3318
Fax: (215) 349-5849
Patient appointments: 800-789-7366 (PENN)