Jan-Karl Burkhardt, MD
Neurosurgery
Accepting new patients
Sees patients age 18 and up
Penn Neuroscience Center - Neurosurgery
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Penn Medicine Provider

About me

  • Division Head, Cerebrovascular Surgery
  • The James and Agnes Kim Associate Professor of Neurosurgery
  • Associate Professor of Radiology

Education and training

  • Medical School: University of Leipzig
  • Residency: University Hospital Zurich
  • Fellowship: University of California San Francisco
  • Fellowship: NYU Langone Medical Center

What my patients think about me

Average Rating

406 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

December 2025
dr. burkhardt is remarkable. for a busy neurosurgeon he seems genuinely interested in his patient and not in a big hurry, though i am sure he has plenty of cases to manage.
December 2025
one human being communicating to another
December 2025
dr inspired confidence, had good bedside manner, answered questions
December 2025
he is very knowledgeable but also very personable and easy to understand.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Lancaster General Hospital: Has privileges to treat patients in the hospital.
Dr. Burkhardt is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Wu AQ, Gitlevich R, Palepu C, Hoglund ZT, Sollenberger CH, Kahlon AS, Scott KW, Ehtiati T, Burkhardt JK, Catapano JS, Kandregula S, Favilla CG, Srinivasan VM. Mapping real-time hemodynamic changes in venous sinus stenting using intraoperative transcranial Doppler ultrasonography and quantitative angiography , Neurosurg Focus, 60: 2026,E10


Kayir I, Italia T, Gajjar AA, Mehta A, Patel S, Patel S, Ciobanu-Caraus O, Jabarkheel R, Shekhtman O, Wu AQ, Scott K, Ajmera S, Kandregula S, Rahmani R, Burkhardt JK, Srinivasan VM, Catapano JS. Efficacy of carotid devices for resistant hypertension: a systematic review , J Neurointerv Surg: 2026


Diana F, Siddiqui AH, Jaikumar V, Baig AA, Tomasello A, Hernandez D, Requena M, de Dios Lascuevas M, Arikan F, Xu B, Liao Y, Raz E, Chung C, Nossek E, Stroh-Holly N, Gmeiner M, Civelli V, Arpaia F, Khattar NK, Hoffman HA, Nickele CM, Arthur AS, Charbel FT, Vajkoczy P, Sanchin A, Jabbour P, Lanzino G, Ransom RC, Raabe A, Petutschnigg T, Velinov N, Burkhardt JK, Hassan AE, Saei H, Salcuni A, Manfrini E, Eusebi P, Bonura A, Romoli M, Peschillo S. Associated Risks to the Treatment of Unruptured Intracranial Aneurysms (MARTA) Score: Development and External Validation , Neurosurgery: 2026


Musmar B, Roy JM, Abdalrazeq H, Yacoub C, Adeeb N, Fuleihan AA, Koduri S, Baldassari M, Lan M, Patel P, Momin AA, Atallah E, Alshahrani R, Karadimas S, Sizdahkhani S, Garg A, Naamani KE, Chen CJ, Jabre R, Saad H, Grossberg JA, Dmytriw AA, Patel AB, Khorasanizadeh M, Ogilvy CS, Thomas AJ, Monteiro A, Siddiqui A, Cortez GM, Hanel RA, Kasem RA, Porto G, Spiotta AM, Piscopo AJ, Hasan DM, Ghorbani M, Weinberg J, Nimjee SM, Bekelis K, Salem MM, Burkhardt JK, Zetchi A, Matouk C, Howard BM, Lai R, Du R, Abbas R, Amllay A, Munoz A, Herial NA, Tjoumakaris SI, Gooch MR, Notarianni C, Guthikonda B, Morcos J, Rosenwasser RH, Jabbour P. Outcomes of Bypass Surgery in Patients with Moyamoya Syndrome Secondary To Sickle Cell Disease: a Multicenter Study , Transl Stroke Res, 17: 2026,18


Shekhtman O, Matache IM, Sioutas GS, Kandregula S, Muhammad N, Kayir I, Covell M, Capone S, Piavchenko G, Catapano JS, Burkhardt JK, Srinivasan VM. Epigenetic mechanisms in aneurysm formation, growth, and rupture: A systematic review , Interv Neuroradiol: 2025


Essibayi MA, Jabal MS, Jamil H, Salim HA, Musmar B, Adeeb N, Dibas M, Cancelliere NM, Diestro JDB, Algin O, Ghozy S, Lay SV, Guenego A, Renieri L, Carnevale J, Saliou G, Mastorakos P, Naamani KE, Momin AA, Shotar E, Möhlenbruch M, Kral M, Chung C, Salem MM, Lylyk I, Foreman PM, Shaikh H, Župančić V, Hafeez MU, Catapano J, Waqas M, Besler MS, Gunes YC, Rabinov JD, Maingard J, Schirmer CM, Piano M, Kühn AL, Michelozzi C, Starke RM, Hassan A, Ogilvie M, Nguyen A, Jones J, Brinjikji W, Nawka MT, Psychogios M, Ulfert C, Pukenas B, Burkhardt JK, Huynh T, Martinez-Gutierrez JC, Sheth SA, Slawski D, Tawk R, Pulli B, Lubicz B, Panni P, Puri AS, Pero G, Raz E, Griessenauer CJ, Asadi H, Siddiqui A, Levy EI, Khatri D, Haranhalli N, Ducruet AF, Albuquerque FC, Regenhardt RW, Stapleton CJ, Kan P, Kalousek V, Lylyk P, Boddu S, Knopman J, Tjoumakaris SI, Cuellar-Saenz HH, Jabbour PM, Clarençon F, Limbucci N, Pereira VM, Patel AB, Altschul DJ, Dmytriw AA; WorldWideWEB Consortium Collaborators. Factors influencing immediate post-angiographic occlusion outcomes in intracranial aneurysms treated with the woven endobridge device: a multi-center analysis and predictive model from the WorldWideWEB consortium , Neurosurg Rev, 49: 2025,36


Italia T, Kayir I, Chilukuri G, Patel S, Patel SA, Gajjar AA, Jabarkheel R, Eberle A, Marcos-Contreras OA, Scott KW, Kasner SE, Jha RM, Pukenas B, Burkhardt JK, Srinivasan VM, Catapano JS. Blood Biomarkers for Large Vessel Occlusions: A Systematic Review , Stroke Vasc Interv Neurol, 5: 2025,e001863


Goyal AD, Gajjar AA, Muhammad N, Wu AQ, Polavarapu H, Tang O, Salem MM, Paliwoda ED, Gupta N, Doad J, Jankowitz BT, Srinivasan VM, Burkhardt JK. A Three-Decade Analysis of Ischemic Stroke in India: Mortality, Morbidity, and Risk Factors Using the Global Burden of Diseases Study from 1990 to 2019 , J Clin Med, 14: 2025,7807


Karamchandani RR, Wolman DN, Bielinski TM, Goyal N, Rhoten JB, Jayaraman MV, Sidebottom CT, Gross BA, Al-Bayati AR, Doheim MF, Tobin MK, Chinthala A, Gajjar A, Mascitelli J, Webb MR, Burkhardt JK, Scott KW, Srinivasan V, Tonetti D, Koneru M, Altschul DJ, Vaishnav D, Multani S, Theofanis T, Ares WJ, Sone JY, Zand R, Bahrami S, Li J, Defilipp G, Strong D, Torabi R, Moldovan K, Kline KE, Schirmer CM, Nogueira RG, Paul AR, Bohnstedt BN, Hendrix P. Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO-TNK) , Ann Clin Transl Neurol: 2025


Wolman DN, Karamchandani RR, Hemmer S, Bielinski TM, Goyal N, Rhoten JB, Jayaraman MV, Sidebottom CT, Gross BA, Al-Bayati AR, Doheim MF, Tobin MK, Chinthala A, Gajjar A, Mascitelli J, Webb MR, Burkhardt JK, Scott KW, Srinivasan V, Tonetti D, Koneru M, Altschul DJ, Vaishnav D, Multani S, Theofanis T, Ares WJ, Sone JY, Zand R, Bahrami S, Li J, Defilipp G, Strong D, Torabi R, Moldovan K, Schirmer CM, Paul AR, Bohnstedt BN, Nogueira RG, Hendrix P. Tenecteplase Versus Alteplase for First-Pass Reperfusion in Basilar Artery Occlusion Stroke Thrombectomy , Ann Neurol: 2025


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