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James Eric Schmitt, MD, PHD

James Eric Schmitt, MD, PHD Physician

Assistant Professor of Radiology at the Hospital of the University of Pennsylvania Assistant Professor of Psychiatry

Dr. Schmitt is employed by Penn Medicine.

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Clinical Specialties


  • Radiology

Programs & Centers:

Board Certification:

  • Diagnostic Radiology, 2015
  • Neuroradiology, 2017

Clinical Expertise:

  • Angiography
  • Angioplasty
  • Arterial Dissection
  • Biopsy
  • Cryoablation
  • CT Scan (Computed Tomography)
  • CT Scan Guided Biopsy
  • CTA (Computed Tomography Angiography)
  • Diagnostic Imaging
  • Diagnostic Test
  • Embolization
  • Microwave Ablation (MWA)
  • Minimally Invasive Surgery
  • MRA (Magnetic Resonance Angiography)
  • MRI (Magnetic Resonance Imaging)
  • Nuclear Imaging
  • Radiofrequency Ablation (RFA)
  • Stent Placement
  • Steroid Injection
  • Ultrasound
  • X-Ray
Show All Expertise

Practice Locations and Appointments

  • Penn Radiology HUP

    Hospital of the University of Pennsylvania 1st Floor, Dulles Building 3400 Spruce Street Philadelphia, PA 19104 800-789-7366 (PENN)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program
  • Vibra Health Plan

Education and Training

Medical School: Virginia Commonwealth University
Residency: Yale-New Haven Hospital
Residency: Hospital of the University of Pennsylvania


Golden Key International Honor Society, National

Hospital Affiliation

Dr. Schmitt is employed by Penn Medicine.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Neuroradiology, Neurogenetics, Quantitative Genetics

Selected Publications:

Schmitt JE, Raznahan A, Clasen LS, Wallace GL, Pritikin JN, Lee NR, Giedd JN, Neale MC: The Dynamic Associations Between Cortical Thickness and General Intelligence are Genetically-Mediated Cerebral Cortex epub ahead of print : 2019.

Schmitt JE, Neale MC, Clasen LS, Liu S, Seidlitz J, Pritikin JN, Chu A, Wallace GL, Lee NR, Giedd JN, Raznahan A: A Comprehensive Quantitative Genetic Analysis of Cerebral Surface Area in Youth Journal of Neuroscience epub ahead of print : 2019.

Sun D, Ching CRK, Lin A, Forsyth JK, Kushan L, Vajdi A, Jalbrzikowski M, Hansen L, Villalon-Reina JE, Qu X, Jonas RK, van Amelsvoort T, Bakker G, Kates WR, Antshel KM, Fremont W, Campbell LE, McCabe KL, Daly E, Gudbrandsen M, Murphy CM, Murphy D, Craig M, Vorstman J, Fiksinski A, Koops S, Ruparel K, Roalf DR, Gur RE, Schmitt JE, Simon TJ, Goodrich-Hunsaker NJ, Durdle CA, Bassett AS, Chow EWC, Butcher NJ, Vila-Rodriguez F, Doherty J, Cunningham A, van den Bree MBM, Linden DEJ, Moss H, Owen MJ, Murphy KC, McDonald-McGinn DM, Emanuel B, van Erp TGM, Turner JA, Thompson PM, Bearden CE: Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size Molecular Psychiatry epub ahead of print : 2018.

Rosen AF, Roalf DA, Ruparel K, Blake J, Seelaus K, villa P, Cook PA, Davatzikos C, Elliot MA, Garcia de La Garza A, Gennatas ED, Quarmley M, Schmitt JE, Shinohara, Tisdall MD, Craddock C, Gur RE, Gur RC, Satterthwaite TD: Quantitative assessment of structural image quality NeuroImage 169 (1): 407-418,2018.

Schmitt JE, Giedd JN, Raznahan A, Neale MC.: The Genetic Contributions to Maturational Coupling in the Human Cerebrum; A Longitudinal Pediatric Twin Imaging Study Cerebral Cortex : 3184-3191,2018.

Jha SC, Xia K, Schmitt JE, Ahn M, Girault JB, Murphy VA, Li G, Wang L, Shen D, Zou F, Zhu H, Styner M, Knickmeyer RC, Gilmore JH: Genetic influences on neonatal cortical thickness and surface area Human Brain Mapping 39 (12): 4998-5013,2018.

Schmitt JE, Vandekar S, Yi J, Ruparel K, Roalf DR, Whinna D, Souders MC, Satterwaite TD, Prabhakaran K, McDonald-McGinn DM, Zakhai EH, Gur RC, Emanuel BS, Gur RE.: Aberrant Cortical Morphometry in the 22q11.2 Deletion Syndrome. Biological Psychiatry 78 (2): 135-143,2014.

Schmitt JE, Neale MC, Fassassi B, Perez J, Lenroot R, Wells E, Giedd JN.: The dynamic role of genetics on cortical patterning during childhood and adolescence. Proceedings of the National Academy of Sciences of the USA 111 (18): 6774-6779,2014.

Dinglasan LA, Oh J, Schmitt JE, Trerotola SO, Stavropoulos, SW: Complicated IVC filter retrievals: Associated factors identified on pre-retrieval CT. Radiology 266 (1): 347-354,2013.

Yushkevich PA, Pashchinskiy A, Oguz I, Mohan S, Schmitt JE, Stein JM, Zukińá D, Vicory J, McCormick M, Yushkevich N, Schwartz N, Gao Y, Gerig G: User-Guided Segmentation of Multi-modality Medical Imaging Datasets with ITK-SNAP Neuroinformatics 17 (1): 83-102,2019.

Rimol LM, Kremen W, Hagler D, Fennema-Notestine C, Eyler LT, Panizzon M, Neale MC, Schmitt JE, Lyons MJ, Franz CE, Fischl B, Seidman LJ, Makris N, Perry M, Pecheco J, Dale A.: Heritability of cortical thickness in a large adult twin sample: The VETSA Project. Human Brain Mapping : 2007.

Schmitt JE, Lenroot RK, Wallace GL, Ordaz S, Taylor KN, Kabani N, Greenstein D, Lerch JP, Kendler KS, Neale MC, Giedd JN: Identification of genetically mediated cortical networks: a multivariate study of pediatric twins and siblings Cerebral Cortex 18 (8): 1737-1747,2008.

Kendler KS, Schmitt JE, Aggen SA, Prescott CA: Genetic and environmental influences on alcohol, caffeine, cannabis, and nicotine use across the life cycle. Archives of General Psychiatry 65 (6): 674-682,2008.

Schmitt JE, Lenroot RK, Ordaz SE, Wallace GL, Lerch JP, Evans AC, Prom EC, Kendler KS, Neale MC, Giedd JN: Variance decomposition of MRI-based covariance maps using genetically informative samples and structural equation modeling NeuroImage 47 (1): 56-64,2009.

Eyler LT, Prom-Wormley E, Fennema-Notestine C, Fischl B, Franz CE, Lyons MJ, Makris N, Neale MC, Pacheco J, Perry ME, Panizzon MS, Schmitt JE, Seidman LJ, Thermenos H, TsuangMT, Dale AM, Kremen WS.: Genetic patterns of correlation among subcortical volumes in humans: Results from a magnetic resonance imaging twins study. Human Brain Mapping 32 (4): 641-653,2011.

Academic Contact Info

Department of Radiology
Hospital of the University of Pennsylvania
3400 Spruce Street

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)