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James Eric Russell, MD

James Eric Russell, MD Physician

Associate Professor of Medicine

Dr. Russell is employed by Penn Medicine.

Does not see patients

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Hematology

Programs & Centers:

Board Certification:

  • Internal Medicine, 1987
  • Medical Oncology, 1989

Clinical Expertise:

  • Anemia
  • Anemia and Bone Marrow Disorders
  • Anemia of Chronic Disease
  • Anemia of Pregnancy
  • Anticoagulation
  • Antiphospholipid Syndrome
  • Antithrombin Deficiency
  • Aplastic Anemia
  • Autoimmune Hemolytic Anemia
  • B12 Deficiency Anemia
  • Bleeding Disorders
  • Blood Clot
  • Blood Clotting Disorders (Blood Coagulation)
  • Blood Disorders
  • Blood Platelet Disorders
  • Bone Marrow Disorders
  • Bone Marrow Failure Syndromes
  • Coagulation Disorders
  • Cold Agglutinin Disease
  • Cooley's Anemia
  • Cryoglobulinemia
  • Deep Thrombophlebitis
  • Deep Vein Thrombosis
  • Diamond Blackfan Anemia
  • Essential Thrombocytosis
  • Factor Eight Disorder
  • Factor Nine Deficiency
  • Factor V Leiden
  • Fanconi Anemia
  • Folic Acid Deficiency
  • Glucose-6-Phosphate Dehydrogenase Deficiency
  • Hand-Foot Syndrome
  • HELLP Syndrome
  • Hemochromatosis
  • Hemoglobinopathies
  • Hemolytic Anemia
  • Hemolytic Uremic Syndrome
  • Hemophilia
  • Heparin-Induced Thrombocytopenia
  • Hereditary Spherocytosis
  • Hypercoagulable State
  • Idiopathic Thrombocytopenic Purpura
  • Iron Deficiency Anemia
  • Iron Metabolism Disorders
  • Leukocytosis
  • Leukopenia
  • Lupus Anticoagulant
  • Lymphopenia
  • Maternal Anticoagulation
  • Maternal Hematologic Disorders
  • Maternal Thrombophilia
  • Monoclonal Gammopathy of Undetermined Significance
  • Neutropenia
  • Pancytopenia
  • Partial Thromboplastin Time Blood Test
  • Pernicious Anemia
  • Petechiae
  • Polycythemia
  • Porphyria
  • Postthrombotic Syndrome
  • Protein C Deficiency
  • Protein S Deficiency
  • Prothrombin Gene Mutation
  • Pure Red Cell Aplasia
  • Purpura
  • Recurrent Thrombosis
  • Red Blood Cell Disorders
  • Secondary Polycythemia
  • Sickle Cell Diseases
  • Splenic Sequestration
  • Splenomegaly
  • Thalassemias
  • Thrombocytopenia
  • Thrombocytosis
  • Thrombophilia
  • Thrombotic Disorders
  • Thrombotic Thrombocytopenic Purpura
  • Venous-Occlusive Crisis
  • Von Willebrand Disease
  • White Blood Cell Disorders
Show All Expertise

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Stanford University School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American Society for Clinical Investigation, International American Society for Microbiology, International American Society of Hematology, International Cooley's Anemia Foundation, International RNA Society, International

Hospital Affiliation

Dr. Russell is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Description of Research Expertise:


Control and function of human embryonic globin genes.

Key words: Globin, embryonic, sickle cell anemia, thalassemia, mRNA, prothrombin.

Selected Publications:

Jiang, Y., Xu, X.-S., and Russell, J.E.: The high stability of [beta]-globin mRNA requires site-specific binding of factors that remodel the structure of its 3'UTR. The 8th Cooley's Anemia Symposium, New York Academy of Sciences, March 17-19 : 2005.

Jiang, Y., Xu, X.-S., and Russell, J.E.: The high stability of human [beta]-globin mRNA is determined by a specific cis-element within its 3'UTR. 28th Annual Meeting of the National Sickle Cell Disease Program, Cincinnati, April 9-13 : 2005.

He, Z., and Russell, J.E.: Evidence that differential stabilization of [beta]-like globin mRNAs is mediated by specific determinants in their 3'UTRs. 28th Annual Meeting of the National Sickle Cell Disease Program, Cincinnati, April 9-13 : 2005.

Russell, J.E.: Adaptive post-transcriptional processes mitigate globin chain imbalance in [beta]-thalassemic erythrocytes 27th Annual Meeting of the National Sickle Cell Disease Program, Los Angeles, April 18-21 : 2004.

He, Z., and Russell, J.E.: Co-expression of human [zeta] globin corrects the sickle phenotype in mouse models of sickle cell disease 27th Annual Meeting of the National Sickle Cell Disease Program, Los Angeles, April 18-21 : 2004.

Frehm, E.J., Russell, J.E., and Gow, A.J.: Genetic and pharmacologic modulation of nitric oxide-hemoglobin reactivity Eastern Society for Pediatric Research, Old Greenwich CT, March 26-28 : 2004.

Russell, J.E.: Hemoglobinopathies and thalassemias. Medical Knowledge Self-Assessment Program 13 : 30-32,2003.

View all publications

Academic Contact Info

Biomedical Research Building, Room 713
421 Curie Boulevard

Philadelphia, PA 19104
Phone: (215) 898-4406