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James D. Kolker, MD

James D. Kolker, MD Physician

Chief, Section of Radiation Oncology, Pennsylvania Hospital
Medical Director, CyberKnife
Clinical Assistant Professor of Radiation Oncology

Dr. Kolker is a Penn Medicine employed physician.

Clinical Specialties


  • Radiation Oncology

Programs & Centers:

Board Certification:

  • Internal Medicine, 1985
  • Radiation Oncology, 1993

Clinical Expertise:

  • Radiation Treatment

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Jefferson Medical College
Residency: Roger Williams Memorial Medical Center
Residency: University of Chicago Medical Center


American College of Radiology, National American Society of Therapeutic Radiology and Oncology, National Texas Medical Association, Local

Hospital Affiliation

Dr. Kolker is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Cheli CD, Levine RI, Cambetas DR, Kolker JD, Roberts SB.: Age-related reference ranges for complexed prostate-specific antigen and complexed/total prostate-specific antigen ratio: Results from East Texas Medical Center Cancer Institute screening campaign Urology 60(4 Suppl 1) : 53-9,2002.

Kolker JD, Weichselbaum RR.: Brain tumor radiobiology Advances in Neuro-Oncology : 1997.

Yang FE, Vaida F, Ignacio L, Awan A, Culbert H, Nautiyal J, Kolker JD, Sutton H, Halpern H, Weichselbaum RR, Chen GTY, Vijayakumar S.: Acute toxicity in radiotherapy of prostate cancer: Results of a randomized study with and without beam's-eye view three-dimensional conformal therapy Rad Onc Investigations : 1996.

Kolker JD, Sharma J, Cruz R, Diamond AD: Sequence and unusual 3' flanking region of the rattRNA [Ser] Sec gene Gene 164 : 375-376,1995.

Krishnasamy S, Vokes EE, Dohrmann GJ, Mick R, Garcia JC, Kolker JD, Wollman RL, Hekmatpanah J, Weichselbaum RR.: Concomitant chemoradiotherapy, neutron boost, and adjuvant chemotherapy for anaplastic astrocytoma and glioblastoma multiforme Cancer Invest 13(5) : 453-459,1995.

Choi IS, Diamond AD, Kolker JD, Hatfield DL.: Reconstruction of the biosythetic pathway of selenocysteine tRNAs in Xenopus oocytes. Biochemistry 33 (2): 601-605,1994.

Vijayakumar S, Awan A, Karrison K, Culbert H, Chan S, Kolker JD, Low N, Halpern H, Rubin S, Chen GTY, et al.: Acute toxicity during external beam radiotherapy for localized prostate cancer: comparison of different techniques Int J Radiat Oncol Biol Phys 25 : 359-371,1993.

Vokes E, Krishnasamy S, Dolan E, Ratain M, Dohrmann G, Hekmatpanah J, Kolker J, Weichselbaum R, Schilsky R, Berezin F, Walter P, Charlette J.: 5-fluorouracil (5-FU), hydroxyurea (HU) with escalating doses of iododeoxyuridine (IUdR) and concomitant radiotherapy (XRT) for malignant gliomas: A clinical and pharmacological analysis. American Association of Cancer Research : 1992.

Kolker JD, Vokes EE.: Chemotherapy and radiation therapy in the treatment of malignant gliomas of the brain J Infus Chemother 2 : 45-54,1992.

Kies MS, Pelzer H, Kolker JD, Weichselbaum RR, Breit R.: Management of squamous cell carcinoma of the tongue Contemporary Oncol 2 : 55-59,1991.

Academic Contact Info

Penn Radiation Oncology
Pennsylvania Hospital
Widener Ground Level
800 Spruce Street

Philadelphia, PA 19107
Phone: (215) 829-3873
Patient appointments: 800-789-PENN (7366)

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