Penn Medicine Provider
Gastroenterology
James D. Lewis, MD, MSCE
4.9
(138)
Accepting new patients
Sees patients age 18 and up
Penn Gastroenterology Penn Presbyterian
View 1 additional location

About me

  • Chief of Gastroenterology, Penn Presbyterian Medical Center
  • Vice Chief for Research (Clinical), Division of Gastroenterology and Hepatology
  • Professor of Medicine (Gastroenterology)
  • Professor of Epidemiology in Biostatistics and Epidemiology

Education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: Yale-New Haven Hospital
  • Fellowship: Hospital of the University of Pennsylvania

What my patients think about me

Average Rating
4.9

139 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

March 2025
5.0
5.0
have recommended him before
March 2025
5.0
5.0
under this care,i had an amazing turn around in my health.
January 2025
5.0
5.0
expertise, genuine concern for my health and very personable
December 2024
5.0
5.0
dr lewis discussed many things with me, asked relevant questions, and responded appropriately to my answers

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Lewis is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Chassaing B, Compher C, Bonhomme B, Liu Q, Tian Y, Walters W, Nessel L, Delaroque C, Hao F, Gershuni V, Chau L, Ni J, Bewtra M, Albenberg L, Bretin A, McKeever L, Ley RE, Patterson AD, Wu GD, Gewirtz AT, Lewis JD. Randomized controlled-feeding study of dietary emulsifier carboxymethylcellulose reveals detrimental impacts on the gut microbiota and metabolome , Gastroenterology: 2021


Raffals LE, Saha S, Bewtra M, Norris C, Dobes A, Heller C, O'Charoen S, Fehlmann T, Sweeney S, Weaver A, Bishu S, Cross R, Dassopoulos T, Fischer M, Yarur A, Hudesman D, Parakkal D, Duerr R, Caldera F, Korzenik J, Pekow J, Wells K, Bohm M, Perera L, Kaur M, Ciorba M, Snapper S, Scoville EA, Dalal S, Wong U, Lewis JD. The Development and Initial Findings of A Study of a Prospective Adult Research Cohort with Inflammatory Bowel Disease (SPARC IBD) , Inflamm Bowel Dis, 28: 2021,192-199


Lewis JD, Sandler R, Brotherton C, Brensinger C, Li H, Kappelman MD, Daniel SG, Bittinger K, Albenberg L, Valentine JF, Hanson J, Suskind D, Meyer A, Compher CW, Bewtra M, Saxena A, Dobes A, Cohen B, Flynn AD, Fischer M, Saha S, Swaminath A, Yacyshyn B, Scherl E, Horst S, Curtis JR, Braly K, Nessel L, McCauley M, McKeever L, Herfarth H; DINE-CD Study Group. A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults With Crohn's Disease , Gastroenterology: 2021


Tanes C, Bittinger K, Gao Y, Friedman ES, Nessel L, Paladhi UR, Chau L, Panfen E, Fischbach MA, Braun J, Xavier RJ, Clish CB, Li H, Bushman FD, Lewis JD, Wu GD. Role of dietary fiber in the recovery of the human gut microbiome and its metabolome , Cell Host Microbe, ell Host Microbe: 2021,394-407


Scott, F. I., Luo, M., Shah, Y., Lasch, K., Vajravelu, R. K., Mamtani, R., Fennimore, B., Gerich, M. E., Lewis, J. D. Identification of the Most Cost-effective Position of Vedolizumab Among the Available Biologic Drugs for the Treatment of Ulcerative Colitis , J Crohns Colitis, 14(5): 2020,575-587


Scott, F. I., Hans, A. K., Gerich, M. E., Fennimore, B., Mamtani, R., Vajravelu, R. K., Lewis, J. D. Identification of the Most Effective Position for Ustekinumab in Treatment Algorithms for Crohn''s Disease , Clin Gastroenterol Hepatol: 2020


Albenberg L, Brensinger C M, Wu Q, Gilroy E, Kappelman M D, Sandler R S, Lewis J D A Diet Low in Red and Processed Meat Does Not Reduce Rate of Crohn's Disease Flares. , Gastroenterology, 157(1): 2019,128-136.e5


Khan Nabeel, Lee Helen, Trivedi Chinmay, Kavani Himanshu, Medvedeva Elina, Xie Dawei, Lewis James D, Yang Yu-Xiao Mortality Associated With Development of Squamous Cell Cancer in Patients With Inflammatory Bowel Disease Receiving Treatment With Thiopurines. , Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 17(11): 2019,2262-2268


Lewis James D, Scott Frank I, Brensinger Colleen M, Roy Jason A, Osterman Mark T, Mamtani Ronac, Bewtra Meenakshi, Chen Lang, Yun Huifeng, Xie Fenglong, Curtis Jeffrey R Increased Mortality Rates With Prolonged Corticosteroid Therapy When Compared With Antitumor Necrosis Factor-α-Directed Therapy for Inflammatory Bowel Disease. , The American journal of gastroenterology, 113(3): 2018,405-417


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