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Jakub Svoboda, MD

Jakub Svoboda, MD Physician

Professor of Pediatrics

Languages spoken:

  • Czech

Dr. Svoboda is employed by Penn Medicine.

About Dr. Jakub Svoboda

Recognized by America's Top Doctors for 2017

Recognized in Philadelphia magazine's annual Top Docs issues for 2018 and 2019

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties

Clinical Expertise:

  • Adult T-Cell Leukemia
  • Adult T-Cell Lymphoma
  • Anaplastic Large Cell Lymphoma
  • Blood Cancer
  • Bone Marrow Biopsy
  • Burkitt Lymphoma
  • Chronic Lymphocytic Leukemia
  • CNS Lymphoma
  • Cutaneous B Cell Lymphoma
  • Cutaneous Lymphoma
  • Gray Zone Lymphoma
  • Hairy Cell Leukemia
  • Hematologic Malignancies
  • HIV Lymphoma
  • HIV Malignancies
  • Immunotherapy
  • Intraocular Lymphoma
  • Large Granular Lymphocytic Leukemia
  • Lymphoma of Bone
  • Mantle Zone Lymphoma
  • Marginal Zone Lymphoma
  • Mediastinal Lymphoma
  • Mucosa-Associated Lymphoid Tissue Lymphoma
  • Peripheral T-Cell Lymphoma
  • Sezary Syndrome
  • Small Lymphocytic Lymphoma
  • Transformed Lymphoma
  • Waldenstrom Macroglobulinemia (WM)
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Yale University
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American College of Physicians, National American Society of Clinical Oncology, National American Society of Hematology, National Mid-Atlantic Lymphoma Research Consortium, Local National Comprehensive Cancer Network, National North American Hodgkin Lymphoma Consortium, National

Hospital Affiliation

Dr. Svoboda is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Description of Research Expertise:

My research interests focus on improving outcomes in patients with lymphomas using novel agents and immune based therapies. I have served as the principal investigator on several trials including multicenter investigator initiated trial using brentuximab (immunoconjugate) in combination with chemotherapy as frontline treatment for CD30+ B cell lymphomas. I have also conducted a pilot trial using chimeric antigen receptor (CAR) T cells in patients in relapsed/refractory Hodgkin lymphoma and served as co-investigator on trials using CAR T cells in non-Hodgkin lymphomas. More recently, I have been involved in collaborative work with our translational scientists which may allow us to find new therapeutic targets for cellular therapies in Hodgkin lymphoma.

Selected Publications:

Mato AR, Roeker LE, Allan JN, Pagel JM, Brander DM, Hill BT, Cheson BD, Furman RR, Lamanna N, Tam CS, Handunnetti S, Jacobs R, Lansigan F, Bhavsar E, Barr PM, Shadman M, Skarbnik AP, Goy A, Beach DF, Svoboda J, Pu JJ, Sehgal AR, Zent CS, Tuncer HH, Schuster SJ, Pickens PV, Shah NN, Rhodes J, Ujjani CS, Nabhan C.: Outcomes of front line ibrutinib treated CLL patients excluded from landmark clinical trial Am J Hematol 93 (11): 1394-1401,2018.

Shah NN, Nagle SJ, Torigian DA, Farwell MD, Hwang WT, Frey N, Nasta SD, Landsburg D, Mato A, June CH, Schuster SJ, Porter DL, Svoboda J.: Early positron emission tomography/computed tomography as a predictor of response after CTL019 chimeric antigen receptor–T-cell therapy in B-cell non-Hodgkin lymphomas Cytotherapy 20 (12): 1415-1418,2018.

Bange E, Timlin C, Kabel C, Svoboda J, Roeker L, Mato AR.: Evidence for and Against Green Tea and Turmeric in the Management of Chronic Lymphocytic Leukemia Clin Lymphoma Myeloma Leuk 18 (10): e421-e426,2018.

Farhan A, Chong EA, Schuster SJ, Strelec L, Nasta SD, Landsburg D, Svoboda J.: Bexarotene in Patients with Peripheral T-cell Lymphomas: Results of a Retrospective Study Clin Lymphoma Myeloma Leuk 19 (2): 109-115,2019.

Cherng HJ, Sargent RL, Nasta SD, Svoboda J, Schuster SJ, Mato AR, Schrank-Hacker A, Morrissette JJD, Landsburg DJ.: Interim PET/CT Result Is Not Predictive of Survival in Patients With MYC-rearranged Non-Burkitt Aggressive B-cell Lymphoma. Clin Lymphoma Myeloma Leuk 18 (10): 673-678,2018.

Ruan J1, Martin P1, Christos P2, Cerchietti L1, Tam W3, Shah B4, Schuster SJ5, Rodriguez A1, Hyman D1, Calvo-Vidal MN1, Smith SM6, Svoboda J4, Furman RR1, Coleman M1, Leonard JP1.: Five-year follow-up of lenalidomide plus rituximab as initial treatment for mantle cell lymphoma. Blood 132 (19): 2016-2025,2018.

Svoboda J, Rheingold SR, Gill SI, Grupp SA, Lacey SF, Kulikovskaya I, Suhoski MM, Melenhorst JJ, Loudon B, Mato AR, Nasta SD, Landsburg DJ, Youngman MR, Levine BL, Porter DL, June CH, Schuster SJ.: Non-viral RNA chimeric antigen receptor modified T cells in patients with Hodgkin lymphoma. Blood 132 (10): 1022-1026,2018.

Mato AR, Thompson M, Allan JN, Brander DM, Pagel JM, Ujjani CS, Hill BT, Lamanna N, Lansigan F, Jacobs R, Shadman M, Skarbnik AP, Pu JJ, Barr PM, Sehgal AR, Cheson BD, Zent CS, Tuncer HH, Schuster SJ, Pickens PV, Shah NN, Goy A, Winter AM, Garcia C, Kennard K, Isaac K, Dorsey C, Gashonia LM, Singavi AK, Roeker LE, Zelenetz A, Williams A, Howlett C, Weissbrot H, Ali N17, Khajavian S11, Sitlinger A4, Tranchito E7, Rhodes J2, Felsenfeld J3, Bailey N, Patel B, Burns TF, Yacur M, Malhotra M, Svoboda J, Furman RR, Nabhan C.: Real world outcomes and management strategies for venetoclax-treated chronic lymphocytic leukemia patients in the United States. Haematologica 103 (9): 1511-1517,2018.

Bair SM, Mato A, Svoboda J.: Immunotherapy for the Treatment of Hodgkin Lymphoma: An Evolving Paradigm. Clin Lymphoma Myeloma Leuk 18 (6): 380-391,2018.

Jia Ruan, Peter Martin, Paul J Christos, Leandro Cerchietti, Bijal D Shah, Stephen J Schuster, Wayne Tam, Amelyn Rodriguez, David Hyman, Maria Nieves Calvo Vidal, Lidia Roman Gonzalez, Sonali M Smith, Jakub Svoboda, Richard R Furman, Morton Coleman, John P Leonard: Initial Treatment with Lenalidomide Plus Rituximab for Mantle Cell Lymphoma: 5-Year Follow-up and Correlative Analysis from a Multi-Center Phase II Study Blood/American Society of Hematology Annual Meeting, Atlanta, GA 130 : 154-154,2017.

Academic Contact Info

Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-158
3400 Civic Center Boulevard

Philadelphia, PA 19104
Phone: (215) 614-1846
Patient appointments: 800-789-7366

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