Description of Research Expertise:
Anti-inflammatory drugs, cyclooxygenases ,prostaglandins, mechanisms of pain
Barnett RE, Fish D, Katragadda R, Mardini IA: A preemptice approach to stop postoperative pain. A symposium Contemporary Surgery 59 (12) : 559-566,2003.
Aksoy Mark O, Mardini Issam A, Yang Yi, Bin Wei, Zhou Shuangwen: Glucocorticoid effects on the beta-adrenergic receptor-adenylyl cyclase system of human airway epithelium. The Journal of allergy and clinical immunology 109 (3): 491-7,2002.
McAdam B F, Mardini I A, Habib A, Burke A, Lawson J A, Kapoor S: Effect of regulated expression of human cyclooxygenase isoforms on eicosanoid and isoeicosanoid production in inflammation. The Journal of clinical investigation 105 (10): 1473-82,2000.
McAdam B F, Catella-Lawson F, Mardini I A, Kapoor S, Lawson J A: Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proceedings of the National Academy of Sciences of the United States of America 96 (1): 272-7,1999.
Kelsen S G, Higgins N C, Zhou S, Mardini I A: Expression and function of the beta-adrenergic receptor coupled-adenylyl cyclase system on human airway epithelial cells. American journal of respiratory and critical care medicine 152 (6 Pt 1): 1774-83,1995.
Kelsen S G, Zhou S, Anakwe O, Mardini I, Higgins N: Expression of the beta-adrenergic receptor-adenylylcyclase system in basal and columnar airway epithelial cells. The American journal of physiology 267 (4 Pt 1): L456-63,1994.
Mardini I A, Higgins N C, Zhou S, Benovic J L: Functional behavior of the beta-adrenergic receptor-adenylyl cyclase system in rabbit airway epithelium. American journal of respiratory cell and molecular biology 11 (3): 287-95,1994.
Kelsen S G, Sexauer W P, Mardini I A: The comparative effects of elastase-induced emphysema on costal and crural diaphragm and parasternal intercostal muscle contractility. American journal of respiratory and critical care medicine 149 (1): 168-73,1994.
Kelsen S G, Bao S, Thomas A J, Mardini I A: Structure of parasternal intercostal muscles in the adult hamster: topographic effects. Journal of applied physiology (Bethesda, Md. : 1985) 75 (3): 1150-4,1993.
Kelsen S G, Mardini I A, Zhou S, Benovic J L: A technique to harvest viable tracheobronchial epithelial cells from living human donors. American journal of respiratory cell and molecular biology 7 (1): 66-72,1992.