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Perelman Center for Advanced Medicine
Abramson Cancer Center, West Pavilion, 3rd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
A facility of the Hospital of the University of Pennsylvania
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Amy Clark, Igor Makhlin, Angela DeMichele.: Setting the pick: Can PI3K inhibitors circumvent CDK 4/6
inhibitor resistance? Clin Cancer Res 27 (2): 371-373,2021.
Igor Makhlin, Amy Clark, Paul Wileyto, Noah Goodman, John Ndicu, Shannon DeLuca, Candace Clark, S. William Stavropoulos, Natalie Shih, Michael Feldman, Susan Domchek, Jennifer M. Matro, Payal Shah, Hayley Knollman, Kevin Fox, Kara Maxwell, Lewis Chodosh, Angela DeMichele.: Investigating the Clinical Utility of Tumor Mutational Burden in Predicting Rapid Progression and Death in Patients with Metastatic Breast Cancer. San Antonio Breast Cancer Symposium, San Antonio, TX : 2020.
Igor Makhlin, Kevin Fox: Oligometastatic Breast Cancer: Is This a Curable Entity? A Contemporary Review of the Literature Curr Oncol Rep 22 (2): 15,2020.
Igor Makhlin, Angela DeMichele.: On the Rise of Cyclin-Dependent Kinase Inhibitors in Breast Cancer: Progress & Ongoing Challenges. Breast Cancer Management. : 2020.
Igor Makhlin, Ryan D Salinas, Daniel Zhang, Fadi Jacob, Gou-li Ming, Hongjun Song, Deeksha Saxena, Jay F Dorsey, MacLean P Nasrallah, Jennifer JD Morrissette, Zev A Binder, Donald M O'Rourke, Arati S Desai, Steven Brem & Stephen J Bagley.: Clinical activity of the EGFR tyrosine kinase inhibitor osimertinib in EGFRmutant glioblastoma. CNS Oncol 8 (3): CNS43. ,2019.
Arthur J Vaught, Evan M Braunstein, Jagar Jasem, Xuan Yuan, Igor Makhlin, Solange Eloundou, Andrea C Baines, Samuel A Merrill, Shruti Chaturvedi, Karin Blakemore, C John Sperati, Robert A Brodsky.: Germline mutations in the alternative pathway of complement predispose to HELLP syndrome JCI Insight 3 (6): e99128,2018.
Igor Makhlin, Jiaru Zhang, Christopher J Long, Karthik Devarajan, Yan Zhou, Andres J Klein-Szanto, Min Huang, Jonathan Chernoff, Stephen A Boorjian: The mTOR pathway affects proliferation and chemosensitivity of urothelial carcinoma cells and is upregulated in a subset of human bladder cancers BJU Int
108 (2 Pt 2): E:84-90,2011.
Perelman Center for Advanced Medicine 3400 Civic Center Blvd.
Patient appointments: 800-789-7366