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Horace M. DeLisser, MD

Horace M. DeLisser, MD Physician

Associate Professor of Medicine

Dr. DeLisser is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Pulmonary Medicine

Programs & Centers:

Board Certification:

  • Critical Care Medicine, 1991
  • Internal Medicine, 1988
  • Pulmonary Disease, 1990

Clinical Expertise:

  • Alpha-1 Antitrypsin Deficiency
  • Asbestosis
  • Asthma
  • Atelectasis
  • Bronchiectasis
  • Bronchitis
  • Chronic Cough
  • Chronic Obstructive Pulmonary Disease (COPD)
  • Coal Worker's Pneumoconiosis (Black Lung Disease)
  • Diaphragm Injury
  • Drug-Induced Pulmonary Disease
  • Dyspnea
  • Emphysema
  • Empyema
  • Hemoptysis
  • Hypoxia
  • Interstitial Lung Disease
  • Lung Abscess
  • Lung Cancer Screening
  • Lung Disease
  • Lung Nodule
  • Lung Tumors
  • Needle Procedure
  • Occupational Lung Disease
  • Pleural Effusion (Fluid in the Lung)
  • Pleurisy
  • Pneumonia
  • Pulmonary Embolism (Pulmonary Embolus)
  • Pulmonary Fibrosis
  • Pulmonary Hypertension
  • Rheumatoid Lung Disease
  • Silicosis
  • Sleep Disorders
  • Smoking related Disease
  • Tracheal Stenosis
  • Tuberculosis (TB)
  • Whooping Cough
View More

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American College of Physicians, National American Physiological Society, National American Society for Investigative Pathology, National American Thoracic Society, National Association for Academic Minority Physicians, National College of Physicians of Philadelphia, Local Laennec Society, Local Medical Society of Eastern Pennsylvania, Local

Hospital Affiliation

Dr. DeLisser is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Research Interests
[1] Endothelial Cell Adhesion and Motility
[2] Angiogenesis
[3] Tumor Metastasis
[4] Pulmonary Hypertension

Description of Research
PECAM-1 AND ANGIOGENESIS: The formation of blood vessels involves the migration of endothelial cells from preexisting vessels and their subsequent assembly into new vascular channels. PECAM-1 is an endothelial-expressed molecule that appears to play a role in angiogenesis by promoting the efficiency of endothelial cell migration. Current studies in my laboratory investigate the intracellular signaling cascades, triggered by PECAM-1, that promote endothelial cell motility.
PECAM-1 AND TUMOR METASTASIS TO THE LUNG: In an emerging area for our group, recent collaborative efforts by our laboratory have demonstrated that antagonism of PECAM-1 function or loss of its expression on endothelial cells inhibits the development of experimental lung metastases. It appears that the mechanism of this inhibition does not involve an impairment of angiogenesis, but other potential processes that are now the subject of active investigation.
PULMONARY HYPERTENSION: Since 2011, I have served as the Director of Cell Center Core for the Pulmonary Hypertension Breakthrough Initiative located at the University of Pennsylvania. Using techniques we have developed that enable the site-specific isolation of endothelial, smooth muscle and advential cells from the main and types I, II, and III arterial segments, our core has been successfully responsible for isolating, banking and distributing to investigators across the country lung vascular cells. In addition, we have been actively engaged in characterizing the site-specific functional and molecular differences between these cells.

Lab personnel:
Valsamma Abraham, PhD– Senior Investigator
Rahul Kupar, B.S. – Research Specialist

Academic Contact Info

Room 644
6th Floor, South Pavilion, Perelman Center for Advanced Medicine
3400 Civic Center Blvd

Philadelphia, PA 19104-5162
Phone: (215) 898-4409
Patient appointments: 800-789-7366 (PENN)

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