Penn Medicine Provider
Otorhinolaryngology
Gregory S. Weinstein, MD, FACS
5.0
(576)
Accepting new patients
Sees patients age 18 and up
Penn Otorhinolaryngology - Head and Neck Surgery Perelman
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Make an appointmentCall 800-789-7366

About me

  • Director, Penn Center for Head and Neck Cancer
  • Director, Penn Head and Neck Cancer Service Line
  • Professor of Otorhinolaryngology: Head and Neck Surgery at the Hospital of the University of Pennsylvania

Gregory S. Weinstein, MD, serves as professor in the Department of Otorhinolaryngology - Head and Neck Surgery. Dr. Weinstein has been faculty at the University of Pennsylvania since 1991 and is the founding member and co-director of the Penn Center for Head and Neck Cancer, which is an internationally renowned multidisciplinary team for the management of all aspects of care of patients with head and neck cancers. 

Dr. Weinstein's clinical expertise is in the head and neck surgery, including all aspects of cancer surgery oral, pharyngeal, laryngeal and neck cancer as well as special expertise in thyroid and parotid surgery. An extension of Dr. Weinstein's special interest in organ preservation surgery has been clinical research in the area of Transoral Robotic Surgery (TORS). He is principal investigator of the first IRB approved human clinical trial for robotic surgery in the field of Head and Neck Surgery. As co-founder of the first in the world research program in human TORS, he has been involved with clinical research in both developing new techniques, instrumentation, as well as adaptation of laser technology to robotic surgery. Dr. Weinstein has also been involved in establishing the first training program in TORS. Dr. Weinstein has trained physician/researchers from a number of centers around the United States in the TORS techniques and has had trained visiting surgeons in the TORS techniques from Japan, Korea, China, Australia, Sweden, Brazil, France, India as well as others. He has authored numerous articles in the area of robotic surgery and is on the editorial board of the Journal of Robotic Surgery and is a founding Board Member and First President of the SRS (Society for Robotic Society).

Dr. Weinstein is also an international expert in utilizing surgery to preserve the voice box in the face of voice box and throat cancer. He has written the book Organ Preservation Surgery for Laryngeal Cancer, which remains the classic text in this area. He has expertise that allows surgery to get better function and cancer outcomes for the full spectrum of voice box and throat cancers that would otherwise require aggressive radiation or chemoradiation or total removal of the voice box.

America's Top Doctors (book series): 10th Edition, 11th Edition, 12th Edition, 13th Edition, 14th Edition, 1st Edition, 2nd Edition, 3rd Edition, 4th Edition, 5th Edition, 6th Edition, 7th Edition, 8th Edition, 9th Edition

Philadelphia Magazine: 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023

America's Top Doctors for Cancer (book series): 10th Edition, 1st Edition, 2nd Edition, 3rd Edition, 4th Edition, 5th Edition, 6th Edition, 7th Edition, 8th Edition, 9th Edition

Newsweek: 2015

Castle Connolly America's Top Doctors (digital guide): 2016, 2017, 2018, 2019, 2020, 2021

Castle Connolly America's Top Doctors for Cancer (digital guide): 2016, 2017, 2018, 2019, 2020, 2021

Philadelphia Magazine - Cancer Doctors: 2020

Schneps Media - Philadelphia Metro: 2021

Education and training

  • Medical School: New York Medical College
  • Residency: Saint Vincent's Medical Center
  • Residency: University of Iowa Hospitals and Clinics

What my patients think about me

Average Rating
5.0

577 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

April 2025
5.0
5.0
excellent care
April 2025
5.0
5.0
great doctor
April 2025
5.0
5.0
very skilled
April 2025
5.0
5.0
dr. weinstein

Insurance accepted

My Locations

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Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Lancaster General Hospital: Has privileges to treat patients in the hospital.
Dr. Weinstein is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Iocca Oreste, Sollecito Thomas P, Alawi Faizan, Weinstein Gregory S, Newman Jason G, De Virgilio Armando, Di Maio Pasquale, Spriano Giuseppe, Pardiñas López Simón, Shanti Rabie M Potentially malignant disorders of the oral cavity and oral dysplasia: A systematic review and meta-analysis of malignant transformation rate by subtype. , Head & neck, 42(3): 2019,539-555

Gershowitz Jared, Chao Hann-Hsiang, Doucette Abigail, Lukens John N, Swisher-McClure Samuel, Weinstein Gregory S, O'Malley Bert W, Chalian Ara A, Rassekh Christopher H, Newman Jason G, Cohen Roger B, Bauml Joshua M, Aggarwal Charu, Lin Alexander Risk of post-operative, pre-radiotherapy contralateral neck recurrence in patients treated with surgery followed by adjuvant radiotherapy for human papilloma virus-associated tonsil cancer. , The British journal of radiology, 92(1104): 2019,20190466

Shah Ravi R, Weinstein Gregory S, Mirza Natasha A Voice Restoration after Radiation and Supracricoid Partial Laryngectomy by Injection Augmentation of the Arytenoid. , Journal of voice : official journal of the Voice Foundation: 2019

Swisher-McClure Samuel, Lukens John N, Aggarwal Charu, Ahn Peter, Basu Devraj, Bauml Joshua M, Brody Robert, Chalian Ara, Cohen Roger B, Fotouhi-Ghiam Alireza, Geiger Geoffrey, Gershowitz Jared, Livolsi Virginia, Mitra Nandita, Montone Kathleen, Newman Jason, Ojerholm Eric, O'Malley Bert, Rajasekaran Karthik, Tan Erik, Weinstein Gregory, Lin Alexander A Phase 2 Trial of Alternative Volumes of Oropharyngeal Irradiation for De-intensification (AVOID): Omission of the Resected Primary Tumor Bed After Transoral Robotic Surgery for Human Papilloma Virus-Related Squamous Cell Carcinoma of the Oropharynx. , International journal of radiation oncology, biology, physics, 106(4): 2020,725-732

Holsinger F Christopher, Magnuson J Scott, Weinstein Gregory S, Chan Jason Y K, Starmer Heather M, Tsang Raymond K Y, Wong Eddy W Y, Rassekh Christopher H, Bedi Nikita, Hong Steven S Y, Orosco Ryan, O'Malley Bert W, Moore Eric J A Next-Generation Single-Port Robotic Surgical System for Transoral Robotic Surgery: Results From Prospective Nonrandomized Clinical Trials. , JAMA otolaryngology-- head & neck surgery, 145: 2019,1027-1034

Henry Laura E, Haugen Thorsen W, Rassekh Christopher H, Adappa Nithin D, Weinstein Gregory S, O'Malley Bert W A novel transpalatal-transoral robotic surgery approach to clival chordomas extending into the nasopharynx. , Head & neck: 2019

Gomez Ernest D, Thaler Erica R, O'Malley Bert W, Rassekh Christopher H, Weinstein Gregory S, Newman Jason G, Brody Robert M Techniques for developing and viewing stereoscopic three-dimensional teaching videos for transoral robotic surgery (TORS). , Journal of robotic surgery: 2019

Workman Alan D, Brody Robert M, Kuan Edward C, Baranov Esther, Brooks Steven G, Alonso-Basanta Michelle, Newman Jason G, Rassekh Christopher H, Chalian Ara A, Chiu Alexander G, Weinstein Gregory S, Feldman Michael D, Adappa Nithin D, O'Malley Bert W, Palmer James N Sinonasal Undifferentiated Carcinoma: A 15-Year Single Institution Experience. , Journal of neurological surgery. Part B, Skull base, 80(1): 2019,88-95

Charu Aggarwal, Roger B. Cohen, Matthew P. Morrow, Kimberly A. Kraynyak, Albert J. Sylvester, Dawson M. Knoblock, Joshua M. Bauml, Gregory S. Weinstein, Alexander Lin, Jean Boyer, Lindsay Sakata, Sophie Tan, Aubrey Anton, Kelsie Dickerson, Drishty Mangrolia, Russell Vang, Michael Dallas, Sandra Oyola, Susan Duff, Mark Esser, Rakesh Kumar, David Weiner, Ildiko Csiki and Mark L. Bagarazzi Immunotherapy Targeting HPV16/18 Generates Potent Immune Responses in HPV-Associated Head and Neck Cancer. , Clinical Cancer Research, 25(1): 2019,110-124

Chao Hann-Hsiang, Schonewolf Caitlin A, Tan Erik X, Swisher-McClure Samuel, Ghiam Alireza F, Weinstein Gregory S, O'Malley Bert W, Chalian Ara A, Rassekh Christopher H, Newman Jason G, Cohen Roger B, Bauml Joshua M, Aggarwal Charu, Lin Alexander, Lukens John N The impact of treatment package time on locoregional control for HPV+ oropharyngeal squamous cell carcinoma treated with surgery and postoperative (chemo)radiation. , Head & neck, 41(11): 2019,3858-3868

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