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Gregory J. Nadolski, MD

Gregory J. Nadolski, MD Physician

Co-Director, Penn Image-Guided Interventions (PIGI) Laboratory Assistant Professor of Radiology at the Hospital of the University of Pennsylvania

Dr. Nadolski is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Radiology

Programs & Centers:

Board Certification:

  • Diagnostic Radiology, 2013
  • Vascular and Interventional Radiology, 2017

Clinical Expertise:

  • Diagnostic Imaging
  • Liver Cancer
  • Lymphangiography
  • Targeted Molecular Therapy
  • Thoracic Duct Embolization (TDE)
  • Transjugular Intrahepatic Portosystemic Shunts (TIPS)

Description of Clinical Expertise

My research and clinical interests include multimodality therapies for the treatment of hepatocellular carcinoma and liver dominant metastatic cancer.

I have initiated two clinical trials at the Hospital of the University of Pennsylvania for treating hepatocellular carcinoma. One involves combining transcatheter embolization with external beam radiation, and the other combines transcatheter embolization with an investigational oral chemotherapeutics.

Clinical Trials:
1. A Pilot Trial of Transarterial Chemoembolization With or Without Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma Patients Awaiting Liver Transplantation, Hospital of the University of Pennsylvania (UPCC16213)

2. Phase I-II Clinical Trial of the Safety of Hydroxychloroquine Combined with Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma, Hospital of the University of Pennsylvania (UPCC22213)

My other area of clinical and research interest is lymphatic injury, dysfunction, and malformations. Clinically, I perform thoracic duct embolization to treat chylothorax. I participate in research investigating novel lymphatic interventions to treat chylothorax, chylous ascites, refractory ascites and protein losing enteropathy.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Indiana University School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American Association for the Study of Liver Disease, National American College of Radiology, National American Medical Association, National American Roentgen Ray Society, National Philadelphia Angiography and Interventional Radiology Society, Local Philadelphia Angiography and Interventional Radiology Society, Local Philadelphia Angiography and Interventional Radiology Society, Local Radiological Society of North America, National SIR: Grant Review Study Section, National Society of Interventional Radiology, National

Hospital Affiliation

Dr. Nadolski is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

In addition to my research investigating lymphatic interventions and multimodality cancer therapies, I also conduct research on vascular remodeling as it relates to hemodialysis access malfunction and peripheral arterial disease.

In this research, I am investigating a minimally invasive near infrared imaging system to evaluate hemodialysis access. The goal of this research is to detect changes in blood vessels that lead to stenosis before it becomes symptomatic. Detection of such changes at any early stage could improve development and monitor response of therapies to treat vascular disease.

Selected Publications:

Nadolski GJ, Ponce-Dorrego MD, Darge K, Biko DM, Itkin M: Validation of the Position of Injection Needles with Contrast-Enhanced Ultrasound for Dynamic Contract-Enhanced MR Lymphangiography JVIR 29 (7): 1028-1030,2018.

Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR: Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue Science Immunology 3 (24): 2018.

G. Nadolski, A. Salute, T. Robertson, S. Trerotola: Initial experience with Arrow ClearClot over-the-wire thrombectomy device in an in vivo model of iliocaval thrombosis JVIR 29 (4): S273,2018.

Voillet V, Buggert M, Slichter CK, Berkson JD, Mair F, Addison MM, Dori Y, Nadolski G, Itkin MG, Gottardo R, Betts MR, Prlic M: Human MAIT cells exit peripheral tissues and recirculate via lymph in steady state conditions JCI Insight 3 (7): 2018.

R. Kiefer, E. Profka, M. Pourfathi, G. Nadolski, S. Hunt, T. Gade: Analysis of in vivo tumor growth kinetics in a diethylnitrosamine-induced, transarterial embolization-treated rat model of hepatocellular carcinoma JVIR 29 (4): S137–S138,2018.

M. Ponce-Dorrego, D. Biko, K. Darge, G. Nadolski, M. Itkin: Confirmation of the needle position for dynamic contrast-enhanced MR lymphangiography using us contrast JVIR 29 (4): S205-6,2018.

A. Smolock, G. Nadolski, M. Itkin: Lymphatic embolization for the treatment of postprocedural inguinal lymphatic leaks JVIR 29 (4): S32–S33,2018.

E. Alexander, G. Nadolski, M. Soulen, S. Stavropoulos, S. Hunt, T. Gade, M. Itkin, S. Shamimi-Noori: Iatrogenic celiac axis and hepatic artery dissections during intra-arterial regional tumor therapies: a 16-year retrospective review JVIR 29 (4): S116–S117,2018.

P. Habibollahi, S Pourhassan Shamchi, S. Hunt, T. Gade, S. Stavropoulos, M. Soulen, G. Nadolski: Association of radiological complete response following locoregional therapy prior to liver transplantation with long-term outcomes of hepatocellular carcinoma patients JVIR 29 (4): S222–S223,2018.

M. Silk, J. Benjamin, D. Ackerman, M. Noji, G. Nadolski, S. Hunt, T. Gade: Developing TACE 2.0: targeting hepatocellular carcinoma epigenetic and ischemia survival pathways JVIR 29 (4): S136,2018.

Academic Contact Info

Hospital of the University of Pennsylvania
Department of Radiology
1 Silverstein
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 662-7892
Patient appointments: 800-789-7366 (PENN)