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Giorgos C. Karakousis, MD

Giorgos C. Karakousis, MD Surgeon

Assistant Professor of Surgery at the Hospital of the University of Pennsylvania

Languages spoken:

  • Greek

Dr. Karakousis is a Penn Medicine employed physician.

Clinical Specialties

Specialty:

  • Surgery
    • Endocrine and Oncologic Surgery

Programs & Centers:

Board Certification:

  • Surgery, 2008

Clinical Expertise:

  • Adrenal Cancer
  • Adrenal Gland Tumors
  • Anal Cancer
  • Bile Duct Cancer
  • Cancer Surgery
  • Colon Cancer
  • Endocrine Tumors
  • Esophageal Cancer
  • Gallbladder Cancer
  • Gastrointestinal Cancer
  • Gastrointestinal Carcinoid Tumor
  • Isolated Limb Perfusion
  • Laparoscopy
  • Liver - Intraarterial Chemotherapy
  • Liver Cancer
  • Melanoma
  • Melanoma Lymph Node Mapping
  • Melanoma Removal Surgery
  • Neuroendocrine Tumors
  • Pancreatic Cancer
  • Parathyroid Surgery
  • Rectal Cancer
  • Sarcoma
  • Small Intestine Cancer
  • Stomach Cancer (Gastric Cancer)
  • Thyroid Cancer

Practice Locations and Appointments

  • Endocrine and Oncologic Surgery

    Abramson Cancer Center Perelman Center for Advanced Medicine, West Pavilion, 4th Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Memorial Sloan-Kettering Cancer Center

Memberships

American College of Surgeons (ACS), National Association for Academic Surgery, National Philadelphia Academy of Surgery, Local Scientific Advisory Board, Melanoma International Foundation, National Society of Surgical Oncology, National

Hospital Affiliation

Dr. Karakousis is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Selected Publications:

Lu H, Liu S, Zhang G, Kwong LN, Zhu Y, Miller JP, Hu Y, Zhong W, Zeng J, Wu L, Krepler C, Sproesser K, Xiao M, Xu W, Karakousis GC, Schuchter LM, Field J, Zhang PJ, Herlyn M, Xu X, Guo W: Oncogenic BRAF-mediated melanoma cell invasion Cell Reports : 2016.

Merlino G, Herlyn M, Fisher DE, Bastian BC, Flaherty KT, Davies MA, Wargo JA, Curiel-Lewandrowski C, Weber MJ, Leachman SA, Soengas MS, McMahon M, Harbour JW, Swetter SM, Aplin AE, Atkins MB, Bosenberg MW, Dummer R, Gershenwald JE, Halpern AC, Herlyn D, Karakousis GC, Kirkwood JM, Krauthammer M, Lo RS, Long GV, McArthur G, Ribas A, Schuchter L, Sosman JA, Smalley KS, Steeg P, Thomas NE, Tsao H, Tueting T, Weeraratna A, Xu G, Lomax R, Martin A, Silverstein S, Turnham T, Ronai ZA: The state of melanoma: challenges and opportunities Pigment Cell Melanoma Research : 2016.

Kaur A, Webster MR, Marchbank K, Behera R, Ndoye A, Kugel CH, Dang VM, Appleton J, O'Connell MP, Cheng P, Valiga AA, Morissette R, McDonnell NB, Ferrucci L, Kossenkov AV, Meeth K, Tang HY, Yin X, Wood WH, Lehrmann E, Becker KG, Flaherty KT, Frederick DT, Wargo JA, Cooper ZA, Tetzlaff MT, Hudgens C, Aird KM, Zhang R, Xu X, Liu Q, Bartlett E, Karakousis G, Eroglu Z, Lo RS, Chan M, Menzies AM, Long GV, Johnson DB, Sosman J, Schilling B, Schadendorf D, Speicher DW, Bosenberg M, Ribas A, Weeraratna AT: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance Nature : 2016.

Zhang G, Frederick DT, Wu L, Wei Z, Krepler C, Srinivasan S, Chae YC, Xu X, Choi H, Dimwamwa E, Ope O, Shannan B, Basu D, Zhang D, Guha M, Xiao M, Randell S, Sproesser K, Xu W, Liu J, Karakousis GC, Schuchter LM, Gangadhar TC, Amaravadi RK, Gu M, Xu C, Ghosh A, Xu W, Tian T, Zhang J, Zha S, Liu Q, Brafford P, Weeraratna A, Davies MA, Wargo JA, Avadhani NG, Lu Y, Mills GB, Altieri DC, Flaherty KT, Herlyn M: Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors Journal of Clinical Investigation : 2016.

Marek AJ, Ming ME, Bartlett EK, Karakousis GC, Chu EY: Acral lentiginous histologic subtype and sentinel lymph node positivity in thin melanoma JAMA Dermatology : 2016.

Datta J, McMillan MT, Ruffolo L, Lowenfeld L, Mamtani R, Plastaras JP, Dempsey DT, Karakousis GC, Drebin JA, Fraker DL, Roses RE: Multimodality therapy improves survival in resected early stage gastric cancer in the United States Annals of Surgical Oncology : 2016.

Budina-Kolomets A, Webster MR, Leu JI, Jennis M, Krepler C, Guerrini A, Kossenkov AV, Xu W, Karakousis GC, Schuchter LM, Amaravadi RK, Wu H, Yin X, Liu Q, Lu Y, Mills GB, Xu X, George DL, Weeraratna AT, Murphy ME: HSP70 inhibition limits FAK-dependent invasion and enhances the response to melanoma treatment with BRAF inhibitors Cancer Research : 2016.

Ecker BL, McMillan MT, Datta J, Mamtani R, Giantonio BJ, Dempsey DT, Fraker DL, Drebin JA, Karakousis GC, Roses RE: Efficacy of adjuvant chemotherapy for small bowel adenocarcinoma: A propensity score-matched analysis Cancer 122 (5): 693-701,2016.

Kuo LE, Simmons KD, Wachtel H, Zaheer S, Karakousis GC, Fraker DL, Kelz RR: Racial disparities in initial presentation of benign thyroid disease for resection Annals of Surgical Oncology : 2016.

Newton AD, Bartlett EK, Karakousis GC: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a review of factors contributing to morbidity and mortality Journal of Gastrointestinal Oncology 7 (1): 99-111,2016.

Academic Contact Info

Division of Endocrine & Oncologic Surgery
Hospital of the University of Pennsylvania
3400 Spruce St., 4 Silverstein

Philadelphia, PA 19104
Phone: (215) 662-2083
Fax: (215) 662-7476
Patient appointments: 800-789-PENN (7366)

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