Gary D. Wu, MD

Gastroenterology
Penn Medicine Provider

About me

  • Associate Chief for Research, Division of Gastroenterology
  • Associate Director, Center for Molecular Studies in Digestive and Liver Disease
  • Director, Molecular Biology Core
  • Ferdinand G. Weisbrod Professor in Gastroenterology
  • Professor of Medicine in Pediatrics

My education and training

  • Medical School: Northwestern University Feinberg School of Medicine
  • Residency: University of Minnesota
  • Fellowship: University of Michigan Health

Spoken languages

English
English

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Wu is a Penn Medicine physician.

Qualifications and experience

Treatments and conditions

Research

Publications

Kim D, Joe HI, Bae JW, Wu GD, Compher CW, Koo H. Fermented food microbiome: influence on oral and gut microbiota, and human health , Nat Rev Microbiol: 2026


Boyle NR, Sekela JJ, Wang M, Mannochio-Russo H, Pyo JJ, Kim MS, Tian S, Koo I, Friedman ES, Tanes C, Anitha M, Tian Y, Morgan EW, Murray IA, Zackular JP, Bittinger K, Lewis JD, Perdew GH, Wu GD, Zemel BS, Dorrestein PC, Bisanz JE, Redinbo MR, Patterson AD. Glucuronidation metabolomic fingerprinting to map host-microbe metabolism , Nat Commun, 17: 2026,6646


Damani RA, Vasisht S, Luks V, Vargas G, Compher C, Titchenell PM, Tasian G, Li H, Wu GD, Witschey WR, Gershuni VM. Sex-Based Differences in Imaging-Derived Body Composition and Their Association with Clinical Malnutrition in Abdominal Surgery Patients , Nutrients, 18: 2026,839


Firrman J, Liu L, Mahalak K, Lemons JMS, Narrowe A, Friedman ES, Wu GD, Van de Weile T. An in vitro model of the small intestinal microbiota provides key insights into interindividual variability in structure and function , mSystems, 11: 2026,e0137325


Mayer LS, Arnold J, Roettele F, Reuter N, Pattekar A, Ohtani T, Ribeiro MM, Siwicki R, Bruder K, Obwegs D, Stahl E, Buechel S, Roehlen N, Kolter J, Mansoori Moghadam Z, Alaswad A, Zhumalidova Z, Li G, Liu X, Li Y, Singh A, Villacorta Hidalgo J, Paraskevopoulou MD, Yajnik V, Juarez J, Ren Y, Li H, Wherry EJ, Lewis JD, Wu GD, Bewtra M, Tomov VT, Thimme R, Bengsch B, Hasselblatt P, Picelli S, Hofmann M, Sagar. Single-cell profiling reveals diverse γδ T cell subsets in ulcerative colitis , Sci Immunol, 11: 2026,eadx8474


Hantsoo L, Ford E, Friedman ES, Hao F, Patterson AD, Bittinger K, Wu GD, Zemel BS, Tanes C. The impact of adverse childhood experiences on gut microbiota and markers of inflammation is mediated by obesity and depression , Brain Behav Immun: 2026


Zemel BS, Wu GD, Ford E, Tanes C, DeRusso PA, Kelly A Early infant appetitive traits are associated with growth status and adiposity in African-American infants and toddlers. , Ann Hum Biol. , 52(1): 2025


Tanes C, Li Y, Falk GW, Ginsberg GG, Wang KK, Iyer PG, Lightdale CJ, Del Portillo A, Lagana SM, Wang TC, Rustgi AK, Quante M, Jin Z, Wu GD, Friedman ES, Bittinger K, Li H, Abrams JA. Increased reflux secondary bile acids are associated with changes to the microbiome and transcriptome in Barrett's esophagus. , Gut, 17(1): 2025


Tanes C, Hu W, Friedman E, Hecht A, Daniel S, Clish C, Lewis JD, Wu GD, Bittinger K. Distinguishing diet- and microbe-derived metabolites in the human gut , Microbiome, 13: 2025,206


Harling LC, Hecht AL, Meyer F, Wu GD. Revisiting nitrogen assimilation strategies in the mammalian gut: lessons from Enterobacteriaceae as pathobiont models and a challenge to the limitation paradigm , Arch Microbiol, 207: 2025,203


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