Description of Research Expertise:
I have an academic focus limited to breast cancer. My research interests have been focused on shortening radiation courses by hypofractionation, intensity modulated radiation therapy (IMRT) with concurrent boost, proton beam radiation, and cardiac effects of radiation therapy/techniques to reduce cardiac dose in breast cancer. I have published over 75 peer-reviewed manuscripts, review articles and book chapters about breast cancer, radiation for early and advanced stage disease, radiation for intact breast and post-mastectomy indications, and radiation therapy techniques and side effects. I am co-chair of the Radiation Oncology breast committee with responsibility for the written board examination for the American Board of Radiology. I am a member of the NRG breast cancer committee, co-author and co-Radiation Oncology principle investigator for protocol RTOG 1005 A Phase III Trial of Accelerated Whole Breast Irradiation With Hypofractionation Plus Concurrent Boost Versus Standard Whole Breast Irradiation Plus Sequential Boost For Early-Stage Breast Cancer.
Barsky AR, O’Grady F, Kennedy C, Taunk NK, Dong L, Metz JM, Li T, Freedman GM.: Initial clinical experience treating patients with breast cancer on a 6MV flattening filter free O-ring linear accelerator Advances in Radiation Oncology Advances in Radiation Oncology : 2019.
Dreyfuss AD, Barsky A, Taunk NK, , Clark A, Freedman GM: The efficacy and safety of hypofractionated radiotherapy with concurrent anti-HER-2 therapy following breast-conserving therapy for breast cancer The Breast Journal : 2019.
Demissei BG, Freedman G, Feigenberg SJ, Plastaras JP, Maity A, Smith AM, McDonald C, Sheline K, Simone CB, Lin L, Carver JR, Liu P, Zhang L, Bekelman JE, Ky B: Early changes in cardiovascular biomarkers with contemporary thoracic radiation therapy for breast cancer, lung cancer and lymphoma Int J Radiat Oncol Biol Phys : 2018.
Venigalla S, Carmona R, Guttmann DM, Jain V, Freedman GM, Clark AS, Shabason JE: Use and Effectiveness of Adjuvant Endocrine Therapy for Hormone Receptor-Positive Breast Cancer in Men JAMA Oncol : 2018.
Venigalla S, Guttmann DM, Jain V, Sharma S, Freedman GM, Shabason JE: Trends and Patterns of Utilization of Hypofractionated Postmastectomy Radiotherapy: A National Cancer Database Analysis Clin Breast Cancer : 2018.
Baumann BC, Zeng C, Freedman GM, Verginadis II, Macarthur KM, Lin LL, Vachani C, Koumenis C, Solberg TD, Metz JM.: Avoiding antiperspirants during breast radiation therapy: Myth or sound advice? Radiother Oncol : 2017.
Moran MS, Zhao Y, Ma S, Kirova Y, Fourquet A, Chen P, Hoffman K, Hunt K, Wong J, Halasz LM, Freedman G, Prosnitz R Jr, Yassa M, Nguyen DHA, Hijal T, Haffty BG, Wai ES, Truong PT: Association of Radiotherapy Boost for Ductal Carcinoma In Situ With Local Control After Whole-Breast Radiotherapy. JAMA Oncol 3 : 1060-1068,2017.
Vapiwala N, Hwang WT, Kushner CJ, Schnall MD, Freedman GM, Solin LJ.: No impact of breast magnetic resonance imaging on 15-year outcomes in patients with ductal carcinoma in situ or early-stage invasive breast cancer managed with breast conservation therapy Cancer 123 : 1324-1332,2017.
Guttmann D, Gabriel P, Kennedy C, Rate W, Grizos W, Nagda S, Wojtowicz L, Lin L, Freedman GM: Comparison of Acute Toxicities between Contemporary Forward Planned 3D Conformal Radiotherapy and Inverse Planned Intensity Modulated Radiotherapy for Whole Breast Radiation The Breast Journal : 2017.
Konski A, Yu JB, Freedman G, Harrison LB, Johnstone PAS: Radiation Oncology Practice: Adjusting to a New Reimbursement Model J Oncol Practice 12 (5): 474-475,2016.