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Frank E. Silvestry, MD

Frank E. Silvestry, MD Physician

Associate Chief for Education, Cardiovascular Division Director, Cardiovascular Disease Fellowship Program Associate Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Silvestry is employed by Penn Medicine.

About Dr. Frank E. Silvestry

Recognized by America's Top Doctors, 2012 - 2019

Recognized by Best Doctors in America 2003 - 2019

Recognized by Main Line Today Top Doctors 2009 issue

Recognized in Philadelphia magazine's annual Top Docs issues, 2002, and 2012 - 2019

Recognized by Suburban Life magazine's "Top Physicians 2010" issue

Recognized in Delaware Valley Consumers' Checkbook 2003 Top Docs issue

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Cardiology

Programs & Centers:

Board Certification:

  • Cardiovascular Disease, 1997

Clinical Expertise:

  • Abnormal Coronary Angiography
  • Abnormal Stress Test
  • Acute Bacterial Endocarditis
  • Advanced Lipid Testing
  • Amyloidosis
  • Anticoagulation
  • Aortic Disorders
  • Aortic Valve Disorders
  • Aortic Valve Regurgitation
  • Aortic Valve Sclerosis
  • Arrhythmia
  • Atherosclerosis (Arteriosclerosis)
  • Atherosclerosis of the Aorta
  • Athlete's Heart
  • Atrial Fibrillation (Afib)
  • Atrial Flutter
  • Atrial Septal Defect (ASD)
  • Atrial Tachycardia
  • Autoimmune Pericarditis
  • Bicuspid Aortic Valve
  • Bradycardia
  • Cardiac Arrest
  • Cardiac Risk Assessment
  • Cardiac Tumor
  • Cardiovascular Care
  • Carotid Intimal Thickness
  • Chest Pain
  • Chest Pain (Angina)
  • Cholesterol Disorders
  • Cholesterol Management
  • Congestive Heart Failure
  • Coronary Artery Disease
  • Dilated Cardiomyopathy
  • Dobutamine Stress Test
  • Dyspnea On Exertion
  • Electrocardiogram
  • Endocarditis
  • Exercise Intolerance
  • Family History of Heart Disease
  • Fibromuscular Dysplasia
  • Heart Attack (Myocardial Infarction)
  • Heart Health
  • Heart Murmur
  • Heart Problems
  • Holter Monitor
  • Hyperlipidemia Syndrome
  • Hypertension
  • Hypertrophic Cardiomyopathy
  • Idiopathic Hypertrophic Subaortic Stenosis
  • Infiltrative Disorders of the Heart
  • Ischemic Cardiomyopathy
  • Left Bundle Branch Block
  • Left Heart Failure
  • Leg Swelling (Edema)
  • Mitral Regurgitation
  • Mitral Stenosis
  • Mitral Valve Disorders
  • Mitral Valve Prolapse
  • Mitral Valve Regurgitation
  • Myocarditis
  • Myxoma
  • Palpitations
  • Paroxysmal Supraventricular Tachycardia
  • Paroxysmal Tachycardia
  • Patent Foramen Ovale (PFO)
  • Pericardial Effusion
  • Pericarditis
  • Peripheral Edema
  • Peripheral Vascular Diseases
  • Premature Atrial Contraction
  • Premature Beats
  • Premature Ventricular Contractions
  • Preoperative Evaluation
  • Preventative Cardiology
  • Prinzmetals Angina
  • Prosthetic Heart Valves
  • Pulmonary Edema
  • Pulmonary Valve Disorders
  • Pulmonary Valve Insufficiency
  • Pulmonary Valve Stenosis (PVS)
  • Refractory Angina
  • Restrictive Cardiomyopathy
  • Rheumatic Aortic Regurgitation
  • Rheumatic Aortic Stenosis
  • Rheumatic Diseases of Pulmonary Valve
  • Rheumatic Fever
  • Rheumatic Heart Disease
  • Rheumatic Heart Failure
  • Rheumatic Mitral Regurgitation
  • Rheumatic Mitral Stenosis
  • Right Bundle Branch Block
  • Right Heart Failure
  • Right Ventricular Hypertrophy
  • Second Opinion Service
  • Secondary Hypertension
  • Stress Echo Cardiogram
  • Subaortic Stenosis
  • Supraventricular Tachycardia (SVT)
  • Syncope
  • Tachycardia
  • Tachycardia-Bradycardia Syndrome
  • Transcatheter Mitral Valve Repair
  • Transesophageal Echocardiography
  • Transthoracic Echocardiogram
  • Tricuspid Regurgitation
  • Tricuspid Stenosis
  • Tricuspid Valve Disease
  • Unstable Angina
  • Valve Stenosis
  • Valvular Heart Disease
  • Vasovagal Syncope
  • Viral Cardiomyopathy
  • Women's Heart Health
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American Society of Echocardiography, National Fellow, American College of Cardiology (FACC), National Fellow, American Society of Echocardiography (FASE), National

Hospital Affiliation

Dr. Silvestry is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Mitral Valve Disease
Patent Foramen Ovale
Atrial Septal Defect
Structural heart disease
Valvular heart disease
Cardiac Imaging
Intracardiac Echocardiography
Interventional Echocardiography

Selected Publications:

Hanff Thomas C, Kaye David M, Hayward Christopher S, Post Martijn C, Malek Filip, Hasenfuβ Gerd, Gustafsson Finn, Burkhoff Daniel, Shah Sanjiv J, Litwin Sheldon E, Kahwash Rami, Hummel Scott L, Borlaug Barry A, Solomon Scott D, Lam Carolyn S P, Komtebedde Jan, Silvestry Frank E: Assessment of Predictors of Left Atrial Volume Response to a Transcatheter InterAtrial Shunt Device (from the REDUCE LAP-HF Trial). The American journal of cardiology : 2019.

Chen Tiffany, Ferrari Victor A, Silvestry Frank E: Identification and Quantification of Degenerative and Functional Mitral Regurgitation for Patient Selection for Transcatheter Mitral Valve Repair. Interventional cardiology clinics 7 (3): 387-404,2018.

Tiffany Chen, MD and Frank E. Silvestry, MD FACC: Echocardiography in Cardiac Transplantation and Assist Devices (EchoSAP 8) : 2018.

Enriquez Andres, Saenz Luis C, Rosso Raphael, Silvestry Frank E, Callans David, Marchlinski Francis E, Garcia Fermin: Use of Intracardiac Echocardiography in Interventional Cardiology: Working With the Anatomy Rather Than Fighting It. Circulation 137 (21): 2278-2294,2018.

Hirshfeld John W, Fiorilli Paul N, Silvestry Frank E: Important Strategies to Reduce Occupational Radiation Exposure in the Cardiac Catheterization Laboratory: No Lower Limit. Journal of the American College of Cardiology 71 (11): 1255-1258,2018.

Kaye David M, Silvestry Frank E, Gustafsson Finn, Cleland John G, van Veldhuisen Dirk J, Ponikowski Piotr, Komtebedde Jan, Nanayakkara Shane, Burkhoff Dan, Shah Sanjiv J: Impact of atrial fibrillation on rest and exercise haemodynamics in heart failure with mid-range and preserved ejection fraction. European journal of heart failure : 2017.

Kaye David M, Hasenfuß Gerd, Neuzil Petr, Post Martijn C, Doughty Robert, Trochu Jean-Noël, Kolodziej Adam, Westenfeld Ralf, Penicka Martin, Rosenberg Mark, Walton Antony, Muller David, Walters Darren, Hausleiter Jorg, Raake Philip, Petrie Mark C, Bergmann Martin, Jondeau Guillaume, Feldman Ted, Veldhuisen Dirk J van, Ponikowski Piotr, Silvestry Frank E, Burkhoff Dan, Hayward Christopher: One-Year Outcomes After Transcatheter Insertion of an Interatrial Shunt Device for the Management of Heart Failure With Preserved Ejection Fraction. Circulation. Heart failure 9 (12): 2016.

Feldman Ted, Komtebedde Jan, Burkhoff Daniel, Massaro Joseph, Maurer Mathew S, Leon Martin B, Kaye David, Silvestry Frank E, Cleland John G F, Kitzman Dalane, Kubo Spencer H, Van Veldhuisen Dirk J, Kleber Franz, Trochu Jean-Noël, Auricchio Angelo, Gustafsson Finn, Hasenfuβ Gerd, Ponikowski Piotr, Filippatos Gerasimos, Mauri Laura, Shah Sanjiv J: Transcatheter Interatrial Shunt Device for the Treatment of Heart Failure: Rationale and Design of the Randomized Trial to REDUCE Elevated Left Atrial Pressure in Heart Failure (REDUCE LAP-HF I). Circulation. Heart failure 9 (7): 2016.

Rene AG, Jagasia D, Wickramasinghe SR, Desai N, Szeto W, Vallabhajosyula P, Li RH, Silvestry FE, Giri J, Jha S, Herrmann HC, Anwaruddin S1: New Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement J Invasive Cardiol 28 (7): E59-65,2016.

Liang JJ, Silvestry FE.: Mechanistic insights into mitral regurgitation due to atrial fibrillation: "atrial functional mitral regurgitation" Trends Cardiovasc Med : 2016.

View all publications

Academic Contact Info

Cardiovascular Division
Department of Medicine
11-133 South Pavillion PCAM
3400 Civic Center Boulevard
Hospital of the University of Pennsylvania

Philadelphia, PA 19104
Phone: (215) 615-5236
Patient appointments: 800-789-7366 (PENN)

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