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Fiona Simpkins, MD

Fiona Simpkins, MD Physician

Associate Professor of Obstetrics and Gynecology at the Hospital of the University of Pennsylvania

Languages spoken:

  • French

Dr. Simpkins is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties

Specialty:

  • Gynecologic Oncology

Programs & Centers:

Board Certification:

  • Obstetrics and Gynecology - Gynecologic Oncology, 2011
  • Obstetrics and Gynecology, 2009

Clinical Expertise:

  • Abdominal Chemotherapy
  • Adenocarcinoma In Situ of the Cervix
  • Adenocarcinoma of Cervix
  • Adnexal Mass
  • Bartholin's Gland Carcinoma
  • CA 125 Elevation
  • Cancer During Pregnancy
  • Cancer of the Myometrium
  • Cancer of the Oviduct
  • Cervical Cancer
  • Cervical Conization
  • Cervical Dysplasia
  • Cervical Intraepithelial Neoplasia
  • Choriocarcinoma
  • Cold Knife Cone Biopsy of the Cervix
  • Complex Pelvic Surgery
  • Dysgerminoma of Ovary
  • Endometrial Cancer
  • Endometrial Hyperplasia
  • Fallopian Tube Cancer
  • Familial Ovarian Cancer
  • Gestational Trophoblastic Disease
  • Gynecologic Cancer Care
  • Gynecologic Surgery
  • Hereditary Breast and Ovarian Cancer
  • HGSIL Pap Smear
  • Hydatiform Mole
  • Labial Cancer
  • Laparoscopic Oophorectomy
  • Laparoscopic Pelvic Lymphadenectomy
  • Leiomyoma
  • Leiomyosarcoma
  • Leiomyosarcoma of the Uterus
  • Malignant Neoplasm of Mesovarium
  • Ovarian Cancer
  • Ovarian Debulking Surgery
  • Ovarian Tumors
  • Paget's Disease of the Vulva
  • Partial Vulvectomy
  • Pelvic Lymphadenectomy
  • Pelvic Malignancy During Pregnancy
  • Pelvic Mass
  • Postmenopausal Adnexal Mass
  • Primary Peritoneal Cancer
  • Prophylactic Oophorectomy
  • Pseudomyxoma Peritonei
  • Radical Hysterectomy
  • Radical Trachelectomy
  • Radical Vulvectomy
  • Recurrent Cervical Cancer
  • Sentinel Lymph Node Biopsy
  • Squamous Cell Carcinoma of the Cervix
  • Squamous Intraepithelial Neoplasia
  • Surgical Staging
  • Teratoma
  • Teratoma of Ovary
  • Urethral Cancer
  • Uterine Cancer
  • Uterine Mass
  • Vaginal Cancer
  • Vaginal Intraepithelial Neoplasia
  • Vulvar Mass
  • Vulvectomy
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Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Temple University School of Medicine
Residency: Johns Hopkins Hospital
Fellowship: National Institutes of Health
Fellowship: Cleveland Clinic Foundation

Memberships

Alpha Omega Alpha Society Member, National American Board of Obstetrics and Gynecology, Exam writer for written boards, National American College of Obstetricians & Gynecologists, Fellow, National Candidate member, American Society of Clinical Oncologists (ASCO), National NRG (Gynecological Oncology Group) Experimental Therapeutics and Phase 1 Committee Member, National Society of Gynecologic Oncology (SGO), National

Hospital Affiliation

Dr. Simpkins is employed by Penn Medicine.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Selected Publications:

Hyoung Kim, Veena Jagnnathan, Dorothy Halberg, Haineng Xu, Erin George, Sergey Medvedev, Yasuto Kinose, Anne van Harten, Victor Velculesco, Eric Brown, Fiona Simpkins: Optimizing DDRi combinations by genetic context in ovarian cancers from germline BRCA carriers. Basser Symposium for BRCA : 2019.

Arlene Garcia, Natalie MacKenzie, Margaret Whicker, Joseph Lucci, Matt Pearson, Loraine Portelance, Gordon Mills, Lilie Lin, Fiona Simpkins: Phase I clinical trial of nelfinavir and chemoradiation in locally advanced cervix cancer. SGO, Honolulu, HI : 2019.

Yasuto Kinose, Dorothy Hallberg, Gordon Mills, Tan Ince, Victor Velculescu, Fiona Simpkins, Ronny Drapkin: Comprehensive genomic, proteomic, and experimental characterization of ovarian clear cell carcinoma cell lines for improved drug development 12th Biennial Ovarian Cancer Research Symposium presented by the Rifkin center for Ovarian Cancer and the American Association for Cancer Research, Seattle WA : 2018.

Haineng X, Yasuto Kinose, Hyoung Kim, Sergey Medvedev, Erin George, Ronny Drapkin, Eric Brown, Gordon Mills, Fiona Simpkins: A novel treatment approach for targeting Cyclin E over-expressing ovarian cancers 12th Biennial Ovarian Cancer Research Symposium presented by the Rifkin center for Ovarian Cancer and the American Association for Cancer Research, Seattle WA : 2018.

Hyoung Kim, Erin George, Haineng Xu, Sergey Medvedev, Veena Jagannathan, Mark Morgan, Gordon Mills, Eric Brown, Fiona Simpkins: ATR inhibition targets treatment resistant ovarian cancer 12th Biennial Ovarian Cancer Research Symposium presented by the Rifkin center for Ovarian Cancer and the American Association for Cancer Research, Seattle WA : 2018.

*Simpkins F, Jang K, Yoon H, Hew K, Kim M, Azzam D, Sun J, Zhao D, Ince, T, Liu W, Guo W, Zhi Wei, Zhang G, Mills G, *Slingerland JM: *Co-corresponding authors. Dual Src and MEK inhibition decreases ovarian cancer growth and targets tumor initiating stem-like cells. Clin Cancer Res : 2018.

Makvandi M, Pantel A, Schwartz L, Schubert E, Xu K, Hsieh CJ, Hou C, Kim H, Weng CC, Winters H, Doot R, Farwell MD, Pryma DA, Greenberg RA, Mankoff DA, Simpkins F, Mach RH, Lin LL: A PET imaging agent for evaluating PARP-1 expression in ovarian cancer. J Clin Invest : 2018.

George E, Kim H, Ragland R, Butler L, Morgan M, Gilad O, Brown E, Simpkins F: Improving the efficacy of PARP inhibition with a novel ATR inhibitor, ATRN119, in ovarian high grade serous cancers (HGSC). Poster presented at: Society of Gynecologic Oncology, New Orleans, LA, : 2018.

Karakashev S, Zhu H, Yokoyama Y, Zhao B, Fatkhutdinov N, Kossenkov AV, Wilson AJ, Simpkins F, Speicher D, Khabele D, Bitler BG, Zhang R: BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer. Cell Rep 21(12):3398-3405 : 2017.

Garcia-Soto AE, Schreiber T, Strbo N, Ganjei-Azar P, Miao F, Koru-Sengul T, Simpkins F, Nieves-Neira W, Lucci J 3rd, Podack ER: Cancer-testis antigen expression is shared between epithelial ovarian cancer tumors. Gynecol Oncol 145(3):413-419 : 2017.

Academic Contact Info

Jordan Center for Gynecologic Oncology at Penn Perelman Center for Advanced Medicine
3400 Civic Center Blvd., 3rd Floor West

Philadelphia, PA 19104
Phone: (215) 662-3318
Patient appointments: 800-789-7366 (PENN)