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Fiona Simpkins, MD

Fiona Simpkins, MD Physician

Languages spoken:

  • French

Dr. Simpkins is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties

Specialty:

  • Gynecologic Oncology

Programs & Centers:

Board Certification:

  • Obstetrics and Gynecology - Gynecologic Oncology, 2011
  • Obstetrics and Gynecology, 2009

Clinical Expertise:

  • Cervical Cancer
  • Cervical Dysplasia
  • Cervical Lesions
  • Cervix Biopsy
  • Chemotherapy for Gynecologic Cancers
  • Colposcopy
  • Endometrial Cancer
  • Fallopian Tube Cancer
  • Gynecologic Cancer
  • Gynecologic Cancer Surgery
  • Gynecologic Surgery
  • Gynecology Clinical Trials
  • Hysterectomy (Uterus Surgery)
  • Hysteroscopy
  • Laparoscopic Hysterectomy
  • Laparoscopic Supracervical Hysterectomy
  • Laparoscopy
  • Loop Electrosurgical Excision Procedure (LEEP)
  • Minimally Invasive Hysterectomy
  • Ovarian Cancer
  • Robotic Surgery
  • Trophoblastic Cancer
  • Uterine Cancer
  • Vaginal Cancer
  • Vulvar Cancer

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Temple University School of Medicine
Residency: Johns Hopkins Hospital
Fellowship: National Institutes of Health
Fellowship: Cleveland Clinic Foundation

Hospital Affiliation

Dr. Simpkins is employed by Penn Medicine.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Selected Publications:

Kim H, George E, Ragland RL, Rafail S, Zhang R, Krepler C, Morgan M, Herlyn M, Brown EJ, Simpkins F: Targeting the ATR/CHK1 axis with PARP inhibition results in tumor regression in BRCA mutant ovarian cancer models. Clin Cancer Res 23(12):3097-3108 : 2017.

Jang K, Kim M, Gilbert CA, Simpkins F, Ince TA, Slingerland JM: VEGFA activates an epigenetic pathway upregulating ovarian cancer-initiating cells. EMBO Mol Med 9(3):304-318 : 2017.

Rose PG, Ali S, Moslemi-Kebria M, Simpkins F: Paclitaxel, Carboplatin, and Bevacizumab in Advanced and Recurrent Endometrial Carcinoma. Int J Gynecol Cancer 27(3):452-458 : 2017.

Chen J, Solomides C, Simpkins F, Simpkins H: The role of Nrf2 and ATF2 in resistance to platinum-based chemotherapy. Cancer Chemother Pharmacol 79(2):369-380 : 2017.

George E, Kim H, Krepler C, Wenz B, Makvandi M, Tanyi JL, Brown E, Zhang R, Brafford P, Jean S, Mach RH, Lu Y, Mills GB, Herlyn M, Morgan M, Zhang X, Soslow R, Drapkin R, Johnson N, Zheng Y, Cotsarelis G, Nathanson KL, Simpkins F: A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers. JCI Insight 2(1):e89760 (doi: 10.1172/jci.insight.89760): 2017.

Wang Y, Krais JJ, Bernhardy AJ, Nicolas E, Cai KQ, Harrell MI, Kim HH, George E, Swisher EM, Simpkins F, Johnson N: RING domain-deficient BRCA1 promotes PARP inhibitor and platinum resistance. J Clin Invest 1;126(8):3145-57 : 2016.

Dean LT, Zhang X, Latif N, Giuntoli R, Lin L, Haggerty A, Kim S, Shalowitz D, Stashwick C, Simpkins F, Burger R, Morgan M, Ko E, Schmitz K: Race-based disparities in loss of functional independence after hysterectomy for uterine cancer. Support Care Cancer 24(8):3573-80 : ,2016.

George E, Kim H, Ragland R, Brown E, Butler L, Gilad O, Tanyi J, Zhang R, Krepler C, Lee R, Morgan M, Burger R, Ko E, Kim S, Herlyn M, Simpkins F: Capitalizing on synthetic lethality in homologous recombination deficient high grade serous ovarian cancers with a novel ATR inhibitor. Poster and published as abstract for the SGO meeting. San Diego, CA, : 2016.