Find a Cancer Provider

Medical School: Temple University School of Medicine
Residency: Johns Hopkins Hospital
Fellowship: National Institutes of Health
Fellowship: Cleveland Clinic Foundation

Alpha Omega Alpha Society Member, National American Board of Obstetrics and Gynecology, Exam writer for written boards, National American College of Obstetricians & Gynecologists, Fellow, National Candidate member, American Society of Clinical Oncologists (ASCO), National NRG (Gynecological Oncology Group) Experimental Therapeutics and Phase 1 Committee Member, National Society of Gynecologic Oncology (SGO), National

Hospital Privileges:

• Chester County Hospital: Has privileges to treat patients in the hospital.
• Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
• Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Selected Publications:

Hyoung Kim, Veena Jagnnathan, Dorothy Halberg, Haineng Xu, Erin George, Sergey Medvedev, Yasuto Kinose, Anne van Harten, Victor Velculesco, Eric Brown, Fiona Simpkins: Optimizing DDRi combinations by genetic context in ovarian cancers from germline BRCA carriers. Basser Symposium for BRCA : 2019.

Arlene Garcia, Natalie MacKenzie, Margaret Whicker, Joseph Lucci, Matt Pearson, Loraine Portelance, Gordon Mills, Lilie Lin, Fiona Simpkins: Phase I clinical trial of nelfinavir and chemoradiation in locally advanced cervix cancer. SGO, Honolulu, HI : 2019.

Yasuto Kinose, Dorothy Hallberg, Gordon Mills, Tan Ince, Victor Velculescu, Fiona Simpkins, Ronny Drapkin: Comprehensive genomic, proteomic, and experimental characterization of ovarian clear cell carcinoma cell lines for improved drug development 12th Biennial Ovarian Cancer Research Symposium presented by the Rifkin center for Ovarian Cancer and the American Association for Cancer Research, Seattle WA : 2018.

Haineng X, Yasuto Kinose, Hyoung Kim, Sergey Medvedev, Erin George, Ronny Drapkin, Eric Brown, Gordon Mills, Fiona Simpkins: A novel treatment approach for targeting Cyclin E over-expressing ovarian cancers 12th Biennial Ovarian Cancer Research Symposium presented by the Rifkin center for Ovarian Cancer and the American Association for Cancer Research, Seattle WA : 2018.

Hyoung Kim, Erin George, Haineng Xu, Sergey Medvedev, Veena Jagannathan, Mark Morgan, Gordon Mills, Eric Brown, Fiona Simpkins: ATR inhibition targets treatment resistant ovarian cancer 12th Biennial Ovarian Cancer Research Symposium presented by the Rifkin center for Ovarian Cancer and the American Association for Cancer Research, Seattle WA : 2018.

*Simpkins F, Jang K, Yoon H, Hew K, Kim M, Azzam D, Sun J, Zhao D, Ince, T, Liu W, Guo W, Zhi Wei, Zhang G, Mills G, *Slingerland JM: *Co-corresponding authors. Dual Src and MEK inhibition decreases ovarian cancer growth and targets tumor initiating stem-like cells. Clin Cancer Res : 2018.

Makvandi M, Pantel A, Schwartz L, Schubert E, Xu K, Hsieh CJ, Hou C, Kim H, Weng CC, Winters H, Doot R, Farwell MD, Pryma DA, Greenberg RA, Mankoff DA, Simpkins F, Mach RH, Lin LL: A PET imaging agent for evaluating PARP-1 expression in ovarian cancer. J Clin Invest : 2018.

George E, Kim H, Ragland R, Butler L, Morgan M, Gilad O, Brown E, Simpkins F: Improving the efficacy of PARP inhibition with a novel ATR inhibitor, ATRN119, in ovarian high grade serous cancers (HGSC). Poster presented at: Society of Gynecologic Oncology, New Orleans, LA, : 2018.

Karakashev S, Zhu H, Yokoyama Y, Zhao B, Fatkhutdinov N, Kossenkov AV, Wilson AJ, Simpkins F, Speicher D, Khabele D, Bitler BG, Zhang R: BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer. Cell Rep 21(12):3398-3405 : 2017.

Garcia-Soto AE, Schreiber T, Strbo N, Ganjei-Azar P, Miao F, Koru-Sengul T, Simpkins F, Nieves-Neira W, Lucci J 3rd, Podack ER: Cancer-testis antigen expression is shared between epithelial ovarian cancer tumors. Gynecol Oncol 145(3):413-419 : 2017.