Penn Medicine Provider
Gynecologic Oncology
Fiona Simpkins, MD
5.0
(94)
Accepting new patients
Sees patients age 18 and up
Jordan Center for Gynecologic Cancers

About me

  • Hilarie L. and Mitchell L. Morgan President's Distinguished Professor in Women's Health

Education and training

  • Medical School: Temple University School of Medicine
  • Residency: Johns Hopkins Hospital
  • Fellowship: National Institutes of Health
  • Fellowship: Cleveland Clinic Foundation

What my patients think about me

Average Rating
5.0

94 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

May 2025
5.0
5.0
dr simpkins is the best gyn doctor i've ever had.
May 2025
5.0
5.0
Very professional
April 2025
5.0
5.0
dr simpkins has been with me since the beginning of my ovarian cancer diagnosis over 10 years ago. she is the reason i am getting old.
April 2025
5.0
5.0
this was a second opinion and this experience was better than the first

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Chester County Hospital: Has privileges to treat patients in the hospital.
Dr. Simpkins is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Smith AJB, Spataro S, Heintz J, Simpkins F, Ko EM Disparities in clinical drug trial participation in endometrial cancer: a real-world analysis. , Am J Obstet Gynecol.: 2025


Xu H, George E, Gallo D, Medvedev S, Wang X, Kryczka R, Hyer ML, Fourtounis J, Stocco R, Aguado-Fraile E, Petrone A, Yin SY, Shiwram A, Anderson M, Kim H, Liu F, Marshall CG, Simpkins F Targeting CCNE1 amplified ovarian and endometrial cancers by combined inhibition of PKMYT1 and ATR. , Nature Communications: 2025


Smith AJ, Pancoe S, Lynch MP, Wachlin M, Powell K, Hinkle SN, Koelper NC, Doherty M, Bekelman JE, Simpkins F, Ko EM Rideshare services for transportation assistance in gynecologic oncology: a quality improvement study , BMC Health Serv Res: 2025


Kim D, Chung H, Liu W, Jeong K, Ozmen TY, Ozmen F, Rames MJ, Kim S, Guo X, Jameson N, de Jong PR, Yea S, Harford L, Li J, Mathews CA, Doroshow DB, Charles VJ, Kim D, Fischer K, Samatar AA, Jubb A, Bunker KD, Blackwell K, Simpkins F, Meric-Bernstam F, Mills GB, Harismendy O, Ma J, Lackner MR Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers , NPJ Precis Oncol: 2025


Liu YL, Mathews CA, Simpkins F, Cadoo KA, Provencher D, McCormick CC, ElNaggar AC, Altman AD, Gilbert L, Black D, Kabil N, Taylor RN, Barnicle A, Munley JY, Aghajanian C Olaparib as treatment for platinum-sensitive relapsed ovarian cancer by BRCA mutation and homologous recombination deficiency: Phase 2 LIGHT study final overall survival analysis , Cancer: 2025


Weeks JK, Pantel AR, Gitto SB, Liu F, Schubert EK, Pryma DA, Farwell MD, Mankoff DA, Mach RH, Simpkins F, Lin LL [18F]Fluorthanatrace PET in Ovarian Cancer: Comparison with [18F]FDG PET, Lesion Location, Tumor Grade, and Breast Cancer Gene Mutation Status. , J Nucl Med: 2025


Barnicle A, Ray-Coquard I, Rouleau E, Cadoo K, Simpkins F, Aghajanian C, Leary A, Poveda A, Lheureux S, Pujade-Lauraine E, You B, Ledermann J, Matulonis U, Gourley C, Timms KM, Lai Z, Hodgson DR, Elks CE, Dearden S, Egile C, Lao-Sirieix P, Harrington EA, Brown JS Patterns of genomic instability in > 2000 patients with ovarian cancer across six clinical trials evaluating olaparib , Genome Med: 2024


Boland MR, Tubridy E, Solorzano SS, Simpkins F, Smith AJB, Ko EM Geographic Disparities in Gynecologic Oncology Clinical Trial Availability in the US. , JAMA Netw Open: 2024


Kinose Y, Xu H, Kim H, Kumar S, Shan X, George E, Wang X, Medvedev S, Ferman B, Gitto SB, Whicker M, D'Andrea K, Wubbenhorst B, Hallberg D, O'Connor M, Schwartz LE, Hwang WT, Nathanson KL, Mills GB, Velculescu VE, Wang TL, Brown EJ, Drapkin R, Simpkins F. Dual blockade of BRD4 and ATR/WEE1 pathways exploits ARID1A loss in clear cell ovarian cancer. , under review Nature Communications: 2024,27:rs.3.rs-3314138. doi: 10.21203/rs.3.rs-3314138/v1.


Fiona Simpkins, Dimitrios Nasioudis, Stephanie L. Wethington, Lainie P. Martin, Janos L. Tanyi, Nawar A. Latif, Drew A. Torigian, Dalia K. Omran, Diego Rodriguez, Simon Smith, Emma Dean, Susan M. Domchek, Ronny Drapkin, Ie-Ming Shih, Eric J. Brown, Wei-Ting Hwang, Deborah K. Armstrong, Geoffrey Shapiro, Stephanie Gaillard, Robert L. Giuntoli II, Joyce F. Liu Combination ATR and PARP Inhibitor (CAPRI): A phase 2 study of ceralasertib plus olaparib in patients with recurrent, platinum-sensitive epithelial ovarian cancer (Cohort A). , ASCO presentation (ASCO Anual Meeting, June, 2024, Chicago, USA: JCO Abstracts, June, 2024: 2024