Description of Research Expertise:
Clinical/translational research focuses on peripheral nerve repair and regeneration, as well as a variety of projects in cerebrovascular surgery. Collaborative research includes evaluation of safety and efficacy of xenon-CT for cerebral blood flow monitoring in subarachnoid hemorrhage and trauma; evaluation of a noninvasive near-infrared spectroscopy device for detection of intracerebral hematomas; evaluation of brain oxygen tension monitoring in subarachnoid hemorrhage; arterial spin-labelling MR in AVM shunt visualization; MRI evaluation of carotid plaques and hemispheric blood flow before and after carotid endarterectomy; cost-effectiveness analysis of imaging in carotid endarterectomy and cerebral aneurysm repair; clinical outcomes for surgical treatment of patients with intractable occipital neuralgia.
Cullen DK, Huang JH, Zager EL, Browne K, Zhang J, Groff R: Long-term survival and integration of transplanted engineered nervous tissue constructs promotes peripheral nerve regeneration Tissue Eng 15 (7): 1677-85,2009.
Rohan R, Stiefel M, Udoetuk J, Spiotta A, Levine JM, Kofke WA, Zager E, Yang W: Brain oxygen tension and outcome in patients with aneurysmal subarachnoid hemorrhage J Neurosurg 109 (6): 1075-82,2008.
Wolf RL, Wang J, Detre JA, Zager EL: Arteriovenous shunt visualization in arteriovenous malformations with arterial spin-labeling MR Am J Neuroradiol 29 (4): 681-687,2008.
Ranalli NJ, Kline DG, McGarvey ML, Boulis NM: Clinical Problem-Solving: Brachial Plexus Closed Injury and Reconstruction Neurosurgery 62 (6): 1330-1339,2008.
Heuer GG, Stiefel MF, Nagpal S, Basil AK, Smith DS: Carotid endarterectomy under regional anesthesia: A primer for the uninitiated Neurosurg Q 18 (3): 201-206,2008.
Stein S, Burnett M, Riina H, Sonnad S: Completion angiography for surgically-treated cerebral aneurysms: An economic analysis Neurosurgery 61 (6): 1162-1169,2007.
Whitmore RG, Simon SL, Hurst RW, Nisenbaum HL, Kasner SE: Bow hunter’s syndrome caused by accessory cervical ossification: posterolateral decompression and the use of intraoperative Doppler ultrasonography Surg Neurol 67 (2): 169-171,2007.
Pfister BJ, Huang JH, Kameswaran N, Zager EL: Neural engineering to produce in vitro nerve constructs and neurointerface Neurosurgery 60 (1): 137-141,2007.
Magge SN, Chen HI: Dystrophic calcification and infraclavicular brachial plexopathy: case report. Neurosurgery 58 : 1216,2006.
Storm PB, Zager E: Surgical clipping of a PICA aneurysm in a 6-month-old child. Pediatr Neurosurg 42 : 406-8,2006.