Find a Doctor or Practice Location

Medical School: Mayo Medical School
Residency: Mayo Clinic
Fellowship: Mayo Clinic
Fellowship: University of Washington Hospital and Clinics

Abramson Cancer Center of the University of Pennsylvania , National American Academy of Neurology, National American Association for Cancer Research, National American Association for Women Radiologists, National American College of Physicians-American Society of Internal Medicine, National American College of Radiology-Member reviewer ACR Practice Guidelines and Technical Standards: "Screening and Diagnostic Mammography.", National American Medical Association (AMA)2002-2003, Alternate Delegate to the Physican House of Delegates, 2002 AMA Policy Advisor, "Low cost drugs to poor countries during times of pandemic health crisis." Resolution 402 passed AMA-House of Delegates (Annual Meeting 2002). 2000-2001, Alternate Delegate to the Student House of Delegates (Mayo Medical School), National American Roentgen Ray Society, National Association of University Radiologists, National Department of Defense breast cancer grant peer review panel, International Institute for Translational Medicine and Therapeutics, National Mayo Alumni Association, National Minnesota Medical Association (2001-2002) Delegate 1998, Committee on Ethics and Medical-Legal Affairs, Local Radiological Society of North America, National Society for Neuroscience, National Society of Breast Imaging, National Society of Interventional Radiology, National Society of Thoracic Radiology, National The Doctor's Mayo Society of the Mayo Clinic Alumni Association, National

Hospital Privileges:

• Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
• Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
• Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Selected Publications:

McDonald ES, Mankoff D, Makvandi M, Chu W, Chu Y, Mach RH, Zeng C: Sigma-2 ligands and PARP inhibitors synergistically trigger cell death cancer cells Biochem Biophys Res Commun 486 (3): 788-795,2017.

Zuckerman S,Conant EF,Keller B,Weinstein S,McDonald ES.: Implementation of synthesized 2D mammography in a population-based digital breast tomosynthesis screening program Radiology 28 (1): 730-736,2016.

McDonald ES, Mankoff DA, Mach RH: Novel strategies for breast cancer imaging: new imaging agents to guide treatment J Nuc Med 57 : 69S-74S,2016.

McDonald ES, Oustimov A, Weinstein SP, Synnestvedt M, Schnall MD, Conant EF: Effectiveness of digital breast tomosynthesis compared with digital mammography: Outcomes analysis from 3 years of breast cancer screening JAMA Oncology 2 (6): 737-43,2016.

Cruz, L, McDonald, ES, Mick, R, Czerneicki, B: Anti-HER2 Th1 Response is Superior to Breast MRI in Response to Neoadjuvant Chemotherapy in Patients with HER2 Positive Breast Cancer Ann Surg Oncol 24 (4): 1057-1063,2017.

Lowenfeld, L, Zaheer, S, Oechsle, C, Fracol, M, Datta, J, Xu, S, Fitzpatrick, E, Roses, RE, Fisher, CS, McDonald, ES, Zhang, PJ, DeMichele, A, Mick, R, Koski, GK, Czerniecki, BJ.: Addition of Anti-Estrogen Therapy to Anti-HER2 Dendritic Cell Vaccination Improves Regional Nodal Immune Response and Pathologic Complete Response Rate in Patients with ERpos/HER2pos Early Breast Cancer. Oncoimmunology : 2016.

Naha PC, Lau KC, Hsu JC, Hajfathalian M, Mian S, Chhour P, Uppuluri L, McDonald ES, Maidment AD, Cormode DP: Gold silver alloy nanoparticles (GSAN): an imaging probe for breast cancer screening with dual-energy mammography or computed tomography. Nanoscale 8 (28): 13740-54,2016.

Makvandi, M, Xu, K, Lieberman, BP, Anderson, R, Effron, SS, Winters, H, Zeng, C, McDonald, ES, Pryma, DA, Greenberg, RA, Mach, RH.: A radiotracer strategy to quantify PARP-1 expression in vivo provides a biomarker that can enable patient selection for PARP inhibitor therapy. Cancer Research 76 (15): 4516-24,2016.

Pertuz S, McDonald ES, Weinstein SP, Conant EC, Kontos D: Fully-automated quantitative estimation of volumetric breast density from digital breast tomosynthesis images: Preliminary results and comparison with digital mammography and magnetic resonance imaging Radiology 279 (1): 65-74,2016.

Mitsumori LM, McDonald ES, Neligan PC, Maki JH: Lower extremity MR Lymphangiography: Techniques and applications Tech Vasc Inter Radiol 19 (4): 262-272,2016.

Korhonen KE, Weinstein SP, McDonald ES, Conant EF: Strategies to increase cancer detection: Review of true-positive and false-negative results at digital breast tomosynthesis screening Radiographics 36 (7): 1954-1965,2016.

McDonald ES, Hammersley JA, Chou SS, Rahbar H, Scheel JR, Lee CI, Liu CL, Lehman CD, Partridge SC.: Performance of DWI as a Rapid Unenhanced Technique for Detecting Mammographically Occult Breast Cancer in Elevated-Risk Women with Dense Breasts. AJR Am Journal of Roentgenol 207 (1): 205-16,2016.

McDonald ES, Clark A, Tchou J, Zhang, P, Freedman, G.: Clinical diagnosis and management of breast cancer J Nuc Med 57 : 9S-16S,2016.

Conant EF, Keller BM, Pantalone L, Gastounioti A, McDonald ES, Kontos D: Agreement between breast percentage density estimations from standard-dose versus synthetic digital mammograms: Results from a large screening cohort using automated measures Radiology : 2017.

Chudgar, AV, Conant, EF, Weinstein, SP, Keller, BM, Synnestvedt, M, Yamartino, P, McDonald, ES: Digital Breast Tomosynthesis versus Digital Mammography alone Screen Detected Breast Cancers: Assessment of Disease Extent on Contrast-enhanced Magnetic Resonance Imaging. Clinical Radiology S0009-9260 (17): 30078-8,2017.

Chen L, Ray S, Keller BM, Pertuz S, McDonald ES, Conant EF, Kontos D: The Impact of acquisition dose on quantitative breast density estimation with digital mammography: Results from ACRIN PA 4006 Radiology 280 (3): 693-700,2016.

Rahbar, H, McDonald, ES, Lee, JM, Partridge, SC, Lee, CI.: How Can Advanced Imaging Be Used to Mitigate Potential Breast Cancer Overdiagnosis? Academic Radiology 23 (6): 768-73,2016.

McDonald ES, McCarthy AM, Akhtar A, Synnestvedt A, Schnall M, Conant EF: Baseline screening mammography: Performance of full field digital versus digital breast tomosynthesis American Journal of Roentgenology 205 (5): 1143-8,2015.

Zuckerman, S, Weinstein, SW, McDonald, ES, Conant, E: A pictorial essay of synthetic tomosynthesis American Journal of Roent (AJR) : 2016.

Makvandi M, Tilahun ED, Lieberman BP, Anderson RC, Zeng C, Xu K, Hou C, McDonald ES, Pryma DA,Mach RH: The sigma-2 receptor as a therapeutic target for drug delivery in triple negative breast cancer Biochem Biophys Res Commun (BBRC) 467 (4): 1070-1075.,2015.

Mitsumori LM, McDonald ES, Wilson GJ, Neligan PC, Minoshima S, Maki JH: MR Lymphangiography: How I do it J Magn Reson Imaging 42 (6): 1465-77,2015.

Mahrooghy M, Ashraf A, Days D, Mcdonald ES, Rosen M, Mies C, Feldman M, Kontos D. : Pharmacokinetic tumor heterogeneity as a prognostic biomarker for classifying breast cancer recurrence risk IEEE Trans Biomed Eng. 62 (6): 1585-94,2015.

Clark AS, McDonald E, Lynch MC, Mankoff D: Using nuclear medicine imaging in clinical practice: update on PET to guide treatment of patients with metastatic breast cancer Oncology 28 (5): 424-30,2014.

Doot RK, McDonald ES, Mankoff DA: Role of PET quantitation in the monitoring of cancer response to treatment: review of approaches and human clinical trials Clin Transl Imaging 2 (4): 295-303,2014.

McDonald ES, Schopp JG, Peacock S, DeMartini WB, Rahbar H, Lehman CD, Partridge SC: Diffusion-weighted MRI: association between patient characteristics and apparent diffusion coefficients of normal breast fibroglandular tissue at 3 T AJR Am J Roentgenol 202 (5): W496-502,2014.

Mirzabeigi MN, McDonald ES, Chu MW, Fischer JP, Basta M, Kovach S, Wu LC, Serletti J, Kanchwala S: Operative management of locoregional cancer recurrence following post-mastectomy breast reconstruction-indications and outcomes American Society for Reconstructive Microsurgery : 2016.

Derakhshan JJ, McDonald ES, Siegelman ES, Schnall MD, Wehrli FW: Chemical shift artifact of the third kind: Implications for gradient-echo based contrast enhanced imaging ISMRM : 2016.

Partridge SC, McDonald ES: Diffusion weighted magnetic resonance imaging of the breast: protocol optimization, interpretation, and clinical applications Magn Reson Imaging Clin N Am 21 (3): 601-624,2013.