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Elizabeth Hexner, MD

Elizabeth Hexner, MD Physician

Associate Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Hexner is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Hematology
  • Medical Oncology

Programs & Centers:

Board Certification:

  • Hematology, 2017
  • Medical Oncology, 2005

Clinical Expertise:

  • Hematologic Malignancies
  • Leukemia
  • Myeloproliferative Neoplasms (MPN)

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Vetrans Choice Program (6/2018 Not Active)

Education and Training

Medical School: Columbia University
Residency: NewYork-Presbyterian/Columbia University Medical Center
Fellowship: Hospital of the University of Pennsylvania


American Society of Hematology, International Racing to Register, National

Hospital Affiliation

Dr. Hexner is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Myeloproliferative Disorders
Umbilical Cord Blood Transplantation

Selected Publications:

Reilly, C. R., Babushok, D. V., Martin, K., Spivak, J. L., Streiff, M., Bahirwani, R., Mondschein, J., Stein, B., Moliterno, A., Hexner, E. O.: Multicenter analysis of the use of transjugular intrahepatic portosystemic shunt for management of MPN-associated portal hypertension Am J Hematol 92 (9): 909-914,2017.

Verstovsek, S., Mesa, R. A., Gotlib, J., Gupta, V., DiPersio, J. F., Catalano, J. V., Deininger, M. W., Miller, C. B., Silver, R. T., Talpaz, M., Winton, E. F., Harvey, J. H., Jr., Arcasoy, M. O., Hexner, E. O., Lyons, R. M., Paquette, R., Raza, A., Jones, M., Kornacki, D., Sun, K., Kantarjian, H., Comfort- I. investigators: Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial J Hematol Oncol 10 (1): 55,2017.

Hartwell, M. J., Ozbek, U., Holler, E., Renteria, A. S., Major-Monfried, H., Reddy, P., Aziz, M., Hogan, W. J., Ayuk, F., Efebera, Y. A., Hexner, E. O., Bunworasate, U., Qayed, M., Ordemann, R., Wolfl, M., Mielke, S., Pawarode, A., Chen, Y. B., Devine, S., Harris, A. C., Jagasia, M., Kitko, C. L., Litzow, M. R., Kroger, N., Locatelli, F., Morales, G., Nakamura, R., Reshef, R., Rosler, W., Weber, D., Wudhikarn, K., Yanik, G. A., Levine, J. E., Ferrara, J. L.: An early-biomarker algorithm predicts lethal graft-versus-host disease and survival JCI Insight 2 (3): e89798,2017.

Huang, Q., He, S., Tian, Y., Gu, Y., Chen, P., Li, C., Huang, J., Liu, Y., Yu, H., Jin, M., Hu, S., Tong, Q., Ma, A., Jin, J., Hexner, E., Fung, H., Reshef, R., Zhang, Y., Zhang, Y.: Hsp90 inhibition destabilizes Ezh2 protein in alloreactive T cells and reduces graft-versus-host disease in mice Blood : 2017.

Lv, K., Jiang, J., Donaghy, R., Riling, C. R., Cheng, Y., Chandra, V., Rozenova, K., An, W., Mohapatra, B. C., Goetz, B. T., Pillai, V., Han, X., Todd, E. A., Jeschke, G. R., Langdon, W. Y., Kumar, S., Hexner, E. O., Band, H., Tong, W.: CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies Genes Dev 31 (10): 1007-1023,2017.

Gupta, V., Harrison, C., Hexner, E. O., Al-Ali, H. K., Foltz, L., Montgomery, M., Sun, W., Gopalakrishna, P., Kantarjian, H., Verstovsek, S.: The impact of anemia on overall survival in patients with myelofibrosis treated with ruxolitinib in the COMFORT studies Haematologica 101 (12): e482-e484,2016.

Holtan, S. G., Khera, N., Levine, J. E., Chai, X., Storer, B., Liu, H. D., Inamoto, Y., Chen, G. L., Mayer, S., Arora, M., Palmer, J., Flowers, M. E., Cutler, C. S., Lukez, A., Arai, S., Lazaryan, A., Newell, L. F., Krupski, C., Jagasia, M. H., Pusic, I., Wood, W., Renteria, A. S., Yanik, G., Hogan, W. J., Hexner, E., Ayuk, F., Holler, E., Watanaboonyongcharoen, P., Efebera, Y. A., Ferrara, J. L., Panoskaltsis-Mortari, A., Weisdorf, D., Lee, S. J., Pidala, J.: Late acute graft versus host disease: a prospective analysis of clinical outcomes and circulating angiogenic factors Blood : 2016.

Yam, C., Crisalli, L., Luger, S. M., Loren, A. W., Hexner, E. O., Frey, N. V., Mangan, J. K., Gao, A., Stadtmauer, E. A., Porter, D. L., Reshef, R.: Unrelated donors are associated with improved relapse free survival compared to related donors in patients with myelodysplastic syndrome undergoing reduced intensity allogeneic stem-cell transplantation Am J Hematol 91 (9): 883-7,2016.

Hexner, E. O., Luger, S. M., Reshef, R., Jeschke, G. R., Mangan, J. K., Frey, N. V., Frank, D. M., Richman, L. P., Vonderheide, R. H., Aqui, N. A., Rosenbach, M., Zhang, Y., Chew, A., Loren, A. W., Stadtmauer, E. A., Levine, B. L., June, C. H., Emerson, S. G., Porter, D. L.: Infusion of CD3/CD28 co-stimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment Am J Hematol 91 (5): 453-60,2016.

Ganetsky, A., Shah, A., Miano, T. A., Hwang, W. T., He, J., Loren, A. W., Hexner, E. O., Frey, N. V., Porter, D. L., Reshef, R.: Higher tacrolimus concentrations early after transplant reduce the risk of acute GvHD in reduced-intensity allogeneic stem cell transplantation Bone Marrow Transplant 51 (4): 568-72,2016.

Academic Contact Info

Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-106
3400 Civic Center Boulevard

Philadelphia, PA 19104
Phone: (215) 662-6348
Patient appointments: 800-789-7366 (PENN)

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