Selected Publications
Jung, I.-Y., Narayan, V., McDonald S., Rech, A.J., Bartoszek, R., Hong, G., Davis, M.M., Xu, J., Boesteanu, A.C., Barber-Rotenberg, J.S., Plesa, G., Lacey, S.F., Jadlowsky, J.K., Siegel, D.L., Hammill, D., , Cho-Park, P.F., Berger, S.L., Haas, N.B., Fraietta, J.A.: BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T-cell stemness and exhaustion Science Translational Medicine : DOI: 10.1126/scitranslmed.abn7336,2022.
Narayan, V., Barber-Rotenberg, J.S., Jung, I.Y., Lacey, S.F., Rech, A.J., Davis, M.M., Hwang, W.-T., Lai, P., Carpenter, E.L., Maude, S.L., Plesa, G., Vapiwala, N., Chew, A., Moniak, M., Sebro, R.A., Farwell, M.D., Marshall, A., Gilmore, J., Lledo, L., Dengel, K., Church, S.e., Hether, T.D., Xu, J., Gohil, M., Buckingham, T.H., Yee, S.S., Gonzalez, V.E., Kulikovskaya, I., Chen, F., Tian, L., Tien, K., Gladney, W., Nobles, C.L., Raymond, H., Prostate Cancer Cellular Therapy Program Investigators, Hexner, E.O., Siegel, D.L., Bushman, F.D., June, C.H., Fraietta, J.A., Haas, N.B.: PSMA-redirected TGFbeta-insensitive armored CAR T cell to treat metastatic castration resistant prostate cancer Nature Medicine 28 : 724-734,2022.
Herman, J.D., Wang, C., Burke, J.S., Zur, Y., Compere, H., Kang, J., Macvicar, R., Taylor, S., Shin, S., Frank, I., Siegel, D., Tebas, P., Choi, G.H., Shaw, P.A., Yoon, H. Pirofski, L.A., Juelg, B., Bar, K.J., Lauffenburger, D., Alter, G.: Nucleocapsid-specific antibody function is associated with therapeutic benefit from Covid-19 convalescent plasma Cell Reports Med 3 : DOI:https://doi.org/10.1016/j.xcrm.2022.100811,2022.
Melenhorst, J.J., Chen, G.M., Wang, M., Porter, D.L., Gao, P., Bandyopadhyay, S., Pruteanu-Malinici, I., Nobles, C.L., Maji, S., Frey, N.V., Gill, S.I., Tian, L., Kulikovskaya, I., Gupta, M., Davis, M.M., Fraietta, J.A., Brogdon, J.L., Young, R.M., Ambrose, D.E., Chew, A., Levine, B.L., Siegel, D.L., Alanio, C., Wherry, E.J., Bushman, F.D., Lacey, S.F., Tan, K., June, C.H.: Decade-long remissions of leukemia sustained by the persistence of activated CD4+ CAR T-cell Nature 602 : 503-509,2022.
Hsueh, Y.-C., Wang, Y., Riding, R.L., Catalano, D.E., Lu, Y.-J., Richmond, J.M., Siegel, D.L., Rusckowski, M., Stanley, J.R., Harris, J.E.: A keratinocyte-tethered biologic enables location-precise treatment in mouse vitiligo J. Invest. Dermatol j.jid.2022.06.007 : 2022.
Gill, S., Vides, V., Frey, N.V., Hexner, E., Metzger, S., O'Brien, M., Hwang, W-T, Brogdon, J.L., Davis, M.M., Fraietta, J.A., Gaymon, A.L., Gladney, W.L., Lacey, S.F., Lamontagne, A., Mato, A.R., Maus, M.V., Melenhorst, J.J., Pequignot, E., Ruella, M., Shestov, M., Byrd, J.C., Schuster, S.J., Siegel, D.L., Levine, B.L., June, C.H., Porter, D.L.: Anti-CD19 CAR T cells in combination with Ibrutinib for the treatment of chronic lymphocytic leukemia Blood Advances 6 : 5774-5785,2022.
Glassman, P.M., Villa, C.H., Marcos-Contreras, O.A., Hood, E.D., Walsh, L.R., Greineder, C.F., Myerson, J.W., Shuvaeva, T., Puentes, L., Brenner, J.S., Siegel, D.L., Muzykantov, V.R.: Targeted in vivo loading of red blood cells markedly prolongs nanocarrier circulation J. Bioconjugate Chem 33 : 1286-1294,2022.
80., Garfall, A., Cohen, A., Susanibar-Adaniya, S., Hwang, W.-T., Vogl, D., Waxman, A., Lacey, S., Gonzalez, V., Fraietta, J.A., Gupta, M., Kulikovskaya, I., Tian, L., Chen, F., Koterba, N., Bartoszek, R.L., Patchin, M., Xu, R., Plesa, G., Siegel, D.L., Brennan, A., Nelson, A.-M., Ferthio, R., Cosey, A., Shea, K.-M., Leskowitz, R., Four, M., Wilson, W., Miao, F., Lancaster, E., Carreno, B., Linette, G., Hexner, E., Young, R., Bu, D., Mansfield, K., Brogdon, J., June, C., Milone, M.C., Stadtmauer, E.: CAR T cells targeting BCMA and CD19 for newly diagnosed and relapsed multiple myeloma patients responding to current therapy Blood Cancer Discovery : https://doi.org/10.1158/2643-3230.BCD-22-0074,2022.
Tebas, P., Jadlowsky, J.K., Shaw, P.A., Tian, L., Esparza, E., Brennan, A., Kim, S., Naing, S.Y., Richardson, M.W., Vogel, A.N., Maldini, C., Kong, H., Liu, X., Lacey, S.F., Bauer, A.M., Mampe, F., Lee, G., Dale Ando, D., Levine, B.D., Porter, D.L., Zhao, Y., Siegel, D.L., Bar, K.J., June, C.H., Riley, J.L.: CCR5-edited CD4 T cells augment HIV-specific immunity to enable post rebound control of HIV replication J. Clin. Invest. 131 : e144486,2021.
Bhoj, V., Li, L., Parvathaneni, K., Zhang, Z., Kacir, S., Arhontoulis, D., Zhou, K., McGettigan-Croce, B., Nunez-Cruz, S., Gulendran, G., Boesteanu, A.C., Johnson, L., Feldman, M.D., Radaelli, E., Mansfield, K., Nasrallah, M., Goydel, R., Peng, H., Rader, C., Milone, M.C., Siegel, D.L.: Adoptive T cell immunotherapy for medullary thyroid carcinoma targeting GDNF family receptor alpha 4 (GFRa4) Molecular Therapeutic – Oncolytics 20 : 387-398,2021.
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