Selected Publications
Mack, E.A., Dougher, M.C., Ginda, A., Cahill, C., Murter, M., Schell, K., Tanhehco, Y.C., Siegel, D.L., Bhoj, V., Fesnak, A.D., Kambayashi, T., Aqui, N., O’Doherty, U.: Red cell exchange for rapid leukoreduction in adults with hyperleukocytosis and leukostasis Blood 143 : 1049-1054,2024.
Bagley, S.J., Logun, M., Fraietta, J.A., Wang, X., Desai, A.S., Bagley, L.J., Nabavizadeh, A., Jarocha, D., Martins, R., Maloney, E., Lledo, L., Stein, C., Marshall, A., Leskowitz, R., Jadlowsky, J.K., Christensen, S., Oner, B.S., Plesa, G., Brennan, A., Gonzalez, V., Chen, F., Sun, Y., Gladney, W., Barrett, D., Nasrallah, M.P., Hwang, W.-T., Ming, G.-L., Song, H., Siegel, D.L., June, C.H., Hexner, E.O., Binder, Z.A., O'Rourke, D.M.: Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: Phase 1 trial interim results Nature Medicine in press : 2024.
Jung, I.-Y., Bartoszek, R.L., Rech, A., Collins, S.M., Ooi, S.-K., Williams, E.F., Hopkins, C., Narayan, V., Haas, N.B., Frey, N.V., Hexner, E.O., Siegel, D.L., Plesa, G., Porter, D.L., Cantu, A., Everett, J.K., Guedan, S., Berger, S.L., Bushman, F.D., Herbst, F., Fraietta, J.A.: Type I interferon signaling via the EGR2 transcriptional regulator potentiates CAR T cell-intrinsic dysfunction Cancer Discovery 13 : 1636-1655,2023.
Halkidis, K., Meng, C., Liu, S., Mayne, L., Siegel, D.L., Zheng, X.L.: Mechanisms of inhibition of human monoclonal antibodies in immune thrombotic thrombocytopenic purpura Blood 141 : 2993-3005,2023.
Yoshimoto, S., Chester, N., Xiong, A., Radaelli, E., Wang, H., Brillantes, M., Gulendran, G., Glassman, P., Siegel, D.L., Mason, N.J: Development and pharmacokinetic assessment of a fully canine anti-PD-1 monoclonal antibody for comparative translational research in dogs with spontaneous tumors mAbs 15 : e2004638-1 to e2004638-11,2023.
Jung, I.-Y., Noguera-Ortega, E., Bartoszek, R., Collins, S.M., Williams, E., Davis, M., Jadlowsky, J.K., Plesa, G., Siegel, D.L., Chew, A., Levine, B.L., Berger, S.L., Moon, E.K., Albelda, S.M., Fraietta, J.A.: Tissue-resident memory CAR T cells with stem-like characteristics display enhanced efficacy against solid and liquid tumors Cell Reports Medicine 4 : 101053,2023.
Garfall, A., Cohen, A., Susanibar-Adaniya, S., Hwang, W.-T., Vogl, D., Waxman, A., Lacey, S., Gonzalez, V., Fraietta, J.A., Gupta, M., Kulikovskaya, I., Tian, L., Chen, F., Koterba, N., Bartoszek, R.L., Patchin, M., Xu, R., Plesa, G., Siegel, D.L., Brennan, A., Nelson, A.-M., Ferthio, R., Cosey, A., Shea, K.-M., Leskowitz, R., Four, M., Wilson, W., Miao, F., Lancaster, E., Carreno, B., Linette, G., Hexner, E., Young, R., Bu, D., Mansfield, K., Brogdon, J., June, C., Milone, M.C., Stadtmauer, E.: Anti-BCMA/CD19 CAR T Cells with early immunomodulatory maintenance for multiple myeloma responding to initial or later-line yherapy Blood Cancer Discovery 4 : 118-133,2023.
Jung, I.-Y., Narayan, V., McDonald S., Rech, A.J., Bartoszek, R., Hong, G., Davis, M.M., Xu, J., Boesteanu, A.C., Barber-Rotenberg, J.S., Plesa, G., Lacey, S.F., Jadlowsky, J.K., Siegel, D.L., Hammill, D., , Cho-Park, P.F., Berger, S.L., Haas, N.B., Fraietta, J.A.: BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T-cell stemness and exhaustion Science Translational Medicine 14 : DOI: 10.1126/scitranslmed.abn7336,2022.
Narayan, V., Barber-Rotenberg, J.S., Jung, I.Y., Lacey, S.F., Rech, A.J., Davis, M.M., Hwang, W.-T., Lai, P., Carpenter, E.L., Maude, S.L., Plesa, G., Vapiwala, N., Chew, A., Moniak, M., Sebro, R.A., Farwell, M.D., Marshall, A., Gilmore, J., Lledo, L., Dengel, K., Church, S.e., Hether, T.D., Xu, J., Gohil, M., Buckingham, T.H., Yee, S.S., Gonzalez, V.E., Kulikovskaya, I., Chen, F., Tian, L., Tien, K., Gladney, W., Nobles, C.L., Raymond, H., Prostate Cancer Cellular Therapy Program Investigators, Hexner, E.O., Siegel, D.L., Bushman, F.D., June, C.H., Fraietta, J.A., Haas, N.B.: PSMA-redirected TGFbeta-insensitive armored CAR T cell to treat metastatic castration resistant prostate cancer Nature Medicine 28 : 724-734,2022.
Herman, J.D., Wang, C., Burke, J.S., Zur, Y., Compere, H., Kang, J., Macvicar, R., Taylor, S., Shin, S., Frank, I., Siegel, D., Tebas, P., Choi, G.H., Shaw, P.A., Yoon, H. Pirofski, L.A., Juelg, B., Bar, K.J., Lauffenburger, D., Alter, G.: Nucleocapsid-specific antibody function is associated with therapeutic benefit from Covid-19 convalescent plasma Cell Reports Med 3 : DOI:https://doi.org/10.1016/j.xcrm.2022.100811,2022.
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