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Denis Hadjiliadis, MD

Denis Hadjiliadis, MD Physician

Physician Leader, Advanced Lung Disease Research Group Program Director, Adult Cystic Fibrosis Paul F. Harron, Jr. Associate Professor

Languages spoken:

  • French
  • Greek

Dr. Hadjiliadis is employed by Penn Medicine.

About Dr. Denis Hadjiliadis

Recognized by America's Top Doctors 2015 – 2017

Recognized by Best Doctors in America 2017, 2018

Recognized by Philadelphia magazine's annual Top Docs issues, 2015 - 2019

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Pulmonary Medicine

Programs & Centers:

Board Certification:

  • Critical Care Medicine, 2001
  • Pulmonary Disease, 2000

Clinical Expertise:

  • Cystic Fibrosis
  • Lung Transplantation

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Toronto School of Medicine
Residency: Mayo Graduate School of Medicine
Fellowship: Duke University Medical Center
Fellowship: University of Toronto


ADAM Medical Library, Atlanta, GA, National American College of Chest Physicians, International Cystic Fibrosis Foundation Advanced Lung Disease Guidelines, International Cystic Fibrosis Foundation Advanced Lung Disease Guidelines, International Duke University Alumni Association, National European Cystic Fibrosis Society, International Fellow of the Royal College of Physicians of Canada (FRCP(C), International Hellenic Medical Society of Philadelphia, Local Hellenic University Club of Philadelphia, Local International Society for Heart and Lung Transplantation, International International Society of Heart and Lung Transplantation, International Mayo Alumni Association, National Medical Society of Ioannina, Greece, International Member of the Mid-Atlantic Research Group (MaRS) of the Mid-Atlantic CF Consortium, Local Ontario Medical Association, International University of Toronto Alumni Association, International

Hospital Affiliation

Dr. Hadjiliadis is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Cystic Fibrosis
Lung Transplantation
Bronchiolitis Obliterans
Database Analysis

Selected Publications:

Nyirjesy, Sarah C., Sheikh, Saba, Hadjiliadis, Denis, De Leon, Diva D., Peleckis, Amy J., Eiel, Jack N., Kubrak, Christina, Stefanovski, Darko, Rubenstein, Ronald C., Rickels, Michael R., Kelly, Andrea: beta-Cell secretory defects are present in pancreatic insufficient cystic fibrosis with 1-hour oral glucose tolerance test glucose >= 155 mg/dL pediatric diabetes 19 (7): 1173-1182,2018.

Aguilar, Claire A., Hamandi, Bassem, Fegbeutel, Christine, Silveira, Fernand P., Verschuuren, Eric A., Ussetti, Pietat, Chin-Hong, Peter V., Sole, Amparo, Holmes-Liew, C., Billaud, Eliane M., Grossi, Paolo A., Manuel, Oriol, Levine, Deborah J., Barbers, Richard G., Hadjiliadis, Denis, Singer, Lianne G., Husain, Shahid: Clinical risk factors for invasive aspergillosis in lung transplant recipients: Results of an international cohort study journal of heart and lung transplantation 37 (10): 1226-1234,2018.

Hong, Gina, Psoter, Kevin J., Jennings, Mark T., Merlo, Christian A., Boyle, Michael P., Hadjiliadis, Denis, Kawut, Steven M., Lechtzin, Noah: Risk factors for persistent Aspergillus respiratory isolation in cystic fibrosis journal of cystic fibrosis 17 (5): 624-630,2018.

Stephen, Michael J., Long, Alex, Bonsall, Chad, Hoag, Jeffrey B., Shah, Smita, Bisberg, Dorothy, Holsclaw, Douglas, Varlotta, Laurie, Fiel, Stan, Du, Doantrang, Zanni, Robert, Hadjiliadis, Denis: Daily spirometry in an acute exacerbation of adult cystic fibrosis patients chronic respiratory disease 15 (3): 258-264,2018.

Courtwright, Andrew M., Zaleski, Derek, Gardo, Lisa, Ahya, Vivek N., Christie, Jason D., Crespo, Maria, Hadjiliadis, Denis, Lee, James, Molina, Maria, Patel, Namrata, Porteous, Mary, Cantu, Edward E., Bermudez, Christian, Diamond, Joshua M.: Causes, Preventability, and Cost of Unplanned Rehospitalizations Within 30 Days of Discharge After Lung Transplantation transplantation 102 (5): 838-844,2018.

Carrion, Andres, Borowitz, Drucy S., Freedman, Steven D., Siracusa, Christopher M., Goralski, Jennifer L., Hadjiliadis, Denis, Srinivasan, Saumini, Stokes, Dennis C.: Reduction of Recurrence Risk of Pancreatitis in Cystic Fibrosis With Ivacaftor: Case Series journal of pediatric gastroenterology and nutrition 66 (3): 451-454,2018.

Hamandi, B., Fegbeutel, C., Silveira, F. P., Verschuuren, E. A., Younus, M., Mo, J., Yan, J., Ussetti, P., Chin-Hong, P. V., Sole, A., Holmes-Liew, C. L., Billaud, E. M., Grossi, P. A., Manuel, O., Levine, D. J., Barbers, R. G., Hadjiliadis, D., Aram, J., Singer, L. G., Husain, S.: Voriconazole and squamous cell carcinoma after lung transplantation: A multicenter study american journal of transplantation 18 (1): 113-124,2018.

Hong, Gina, Lechtzin, Noah, Hadjiliadis, Denis, Kawut, Steven M: Inhaled antibiotic use is associated with Scedosporium/Lomentospora species isolation in cystic fibrosis. pediatric pulmonology : 2018.

Kelly, Andrea, De Leon, Diva D, Sheikh, Saba, Camburn, Devaney, Kubrak, Christina, Peleckis, Amy J, Stefanovski, Darko, Hadjiliadis, Denis, Rickels, Michael R, Rubenstein, Ronald C: Islet Hormone and Incretin Secretion in Cystic Fibrosis Following 4-months of Ivacaftor Therapy. american journal of respiratory and critical care medicine : 2018.

Law, N., Hamandi, B., Fegbeutel, C., Silveira, F., Verschuuren, E., Ussetti, P., Chin-Hong, P., Sole, A., Holmes-Liew, C. -L., Billaud, E., Grossi, P., Manuel, O., Levine, D., Barbers, R., Hadjiliadis, D., Singer, L., Husain, S.: Clinical Risk Factors for Bronchiolitis Obliterans Syndrome (BOS) in Lung Transplant Recipients (LTRs): Results of an International Cohort Study american journal of transplantation 17 (3): 288,2017.

Academic Contact Info

Hospital of the University of Pennsylvania
3400 Spruce Street
9031A Floor, West Gates Building

Philadelphia, PA 19104
Phone: (215) 662-4202
Patient appointments: 800-789-7366 (PENN)

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