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David S. Frankel, MD

David S. Frankel, MD Physician

Director, Cardiac Electrophysiology Fellowship Program Assistant Professor of Medicine at the Hospital of the University of Pennsylvania

Languages spoken:

  • Hebrew

Dr. Frankel is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties


  • Cardiology

Programs & Centers:

Board Certification:

  • Cardiovascular Disease, 2010
  • Clinical Cardiac Electrophysiology, 2011

Clinical Expertise:

  • Ablation of Idiopathic Ventricular Tachycardia
  • Ablation of Ischemic Ventricular Tachycardia
  • Ablation of Ventricular Tachycardia
  • Atrial Fibrillation (Afib)
  • Atrial Flutter Ablation
  • Biventricular Device Implantation
  • Biventricular Device Optimization
  • Bradycardia
  • Cardiac Catheter Ablation
  • Complex Arrhythmia
  • Electrocardiogram (EKG or ECG)
  • Electrocardiography (ECG or EKG)
  • Electrophysiology (EP) Testing
  • Epicardial Ablation
  • Heart Rhythms - Slow/Fast
  • Implantable Cardioverter Defibrillator
  • Intracardiac Echocardiography (ICE)
  • Pacemaker
  • Pregnancy and Heart Disease
  • Pulmonary Vein Antrum Isolation (PVAI)
  • Radiofrequency Ablation (RFA)
  • Supraventricular Tachycardia (SVT)
  • Syncope (Fainting)
  • Tachycardia
  • Ventricular Tachycardia
  • Wolff-Parkinson-White Syndrome

Description of Clinical Expertise

ventricular tachycardia
atrial fibrillation
catheter ablation
supraventricular tachycardia
cardiac resynchronization therapy

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Massachusetts General Hospital
Fellowship: University of Pennsylvania School of Medicine
Fellowship: Hospital of the University of Pennsylvania


American College of Cardiology , National American Heart Association, National Heart Rhythm Society, National

Hospital Affiliation

Dr. Frankel is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

ventricular tachycardia
atrial fibrillation
catheter ablation
supraventricular tachycardia
pacing-induced cardiomyopathy
cardiac resynchronization therapy

Selected Publications:

Frankel DS, Burke MC, Callans DJ, Stivland TM, Duffy E, Epstein AE.: Impact of Body Mass Index on Safety and Efficacy of the Subcutaneous Implantable Cardioverter-Defibrillator. J Am Coll Cardiol EP : 2018.

Khurshid S, Obeng-Gyimah E, Supple GE, Schaller RD, Lin D, Owens AT, Epstein AE, Dixit S, Marchlinski FE, Frankel DS.: Reversal of Pacing-Induced Cardiomyopathy Following Cardiac Resynchronization Therapy. J Am Coll Cardiol EP : 2018.

Hyman MC, Mustin D, Supple GE, Schaller RD, Santangeli P, Arkles J, Lin D, Muser D, Dixit S, Nazarian S, Epstein AE, Callans DJ, Marchlinski FE, Frankel DS: Class 1C Antiarrhythmic Drugs for Suspected Premature Ventricular Contraction-Induced Cardiomyopathy Heart Rhythm : 2018.

Vakil Kairav, Garcia Santiago, Tung Roderick, Vaseghi Marmar, Tedrow Usha, Della Bella Paolo, Frankel David S, Vergara Pasquale, Di Biase Luigi, Nagashima Koichi, Nakahara Shiro, Tzou Wendy S, Burkhardt J David, Dickfeld Timm, Weiss J Peter, Bunch Jared, Callans David, Lakkireddy Dhanunjaya, Natale Andrea, Sauer William H, Stevenson William G, Marchlinski Francis, Shivkumar Kalyanam, Tholakanahalli Venkatakrishna N: Ventricular Tachycardia Ablation in the Elderly: An International Ventricular Tachycardia Center Collaborative Group Analysis. Circulation. Arrhythmia and electrophysiology 10 (12): 2017.

Sadek Mouhannad M, Cooper Joshua M, Frankel David S, Santangeli Pasquale, Epstein Andrew E, Marchlinski Francis E, Schaller Robert D: Utility of intracardiac echocardiography during transvenous lead extraction. Heart rhythm 14 (12): 1779-1785,2017.

Mandel Jeff E, Stevenson William G, Frankel David S: Anesthesia in the Electrophysiology Laboratory. Anesthesiology clinics 35 (4): 641-654,2017.

Santangeli Pasquale, Zado Erica S, Garcia Fermin C, Riley Michael P, Lin David, Frankel David S, Supple Gregory E, Schaller Robert D, Dixit Sanjay, Callans David J, Marchlinski Francis E: Lack of prognostic value of atrial arrhythmia inducibility and change in inducibility status after catheter ablation of atrial fibrillation. Heart rhythm : 2017.

Maeda Shingo, Chik William W, Liang Jackson J, Kelesidis Iosif, Arroyo Ruben Casado, D'Souza Benjamin, Sadek Mouhannad M, Muser Daniele, Squara Fabien, Venugopal Deviprasad, Santangeli Pasquale, Frankel David S, Zado Erica S, Marchlinski Francis E, Callans David J: Recovery of renal dysfunction after catheter ablation of outflow tract ventricular arrhythmias in patients with ventricular premature depolarization-mediated cardiomyopathy. J Interv Card Electrophysiol 48 (Issue 1): 43–50,2017.

Enriquez Andres, Liang Jackson, Gentile Javier, Schaller Robert D, Supple Gregory E, Frankel David S, Garcia Fermin C, Wald Joyce, Birati Edo Y, Rame J Eduardo, Bermudez Christian, Callans David J, Marchlinski Francis E, Santangeli Pasquale: Outcomes of rescue cardiopulmonary support for periprocedural acute hemodynamic decompensation in patients undergoing catheter ablation of electrical storm. Heart rhythm : 2017.

Vergara Pasquale, Tung Roderick, Vaseghi Marmar, Brombin Chiara, Frankel David, Di Biase Luigi, Nagashima Koichi, Tedrow Usha, Tzou Wendy S, Sauer William H, Mathuria Nilesh, Nakahara Shiro, Vakil Kairav, Tholakanahalli Venkat, Bunch T Jared, Weiss J Peter, Dickfeld Timm, Vunnam Rama, Lakireddy Dhanunjaya, Burkhardt J David, Correra Anna, Santangeli Pasquale, Callans David, Natale Andrea, Marchlinski Francis, Stevenson William G, Shivkumar Kalyanam, Della Bella Paolo: Successful ventricular tachycardia ablation in patients with electrical storm reduces recurrences and improves survival. Heart rhythm : 2017.

Academic Contact Info

Hospital of the University of Pennsylvania
3400 Spruce Street
9 Founders Pavilion

Philadelphia, PA 19104
Phone: (215) 662-6801
Patient appointments: 800-789-7366 (PENN)