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Sees patients age 18 and up
Sees patients age 18 and up
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
A facility of the Hospital of the University of Pennsylvania
Luskin MR, Carroll M, Lieberman D, Morrissette JJD, Zhao J, Crisalli L, Roth DB, Luger SM, Porter DL, Reshef D: Clinical utility of next-generation sequencing for oncogenic mutations in patients with acute myeloid leukemia undergoing allogenic stem cell transplantation Biology of Blood and Marrow Transplantation 22 : 1961-67,2016.
Hiemenz MC, Kadauke S, Lieberman DB, Roth DB, Zhao J, Watt CD, Daber RD, Morrissette JJ: Building a Robust Tumor Profiling Program: Synergy between Next-Generation Sequencing and Targeted Single-Gene Testing PLoS One 11 (4): e0152851,2016.
Roth D: Young but Powerful: Penn Medicine’s Center for Personalized Diagnostics is on a mission to improve patient care using the power of genomics The Pathologist (0316): 402,2016.
Lescale C, Abramowski V, Bedora-Faure M, Murigneux V, Vera G, Roth DB, Revy P, de Villartay JP, Deriano L: RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair Nat Commun 7 (10529): 2016.
Wei S, Lieberman D, Morrissette JJ, Baloch ZW, Roth DB, McGrath C: Using "residual" FNA rinse and body fluid specimens for next-generation sequencing: An institutional experience Cancer Cytopathol : 2015.
Martina Mijušković, Yi-Fan Chou Vered Gigi, Cory R. Lindsay, Olga Shestova, Susanna M. Lewis, David B. Roth: Off target V(D)J recombination drives lymphomagenesis and is escalated by loss of the Rag2 C-terminus Cell Reports 12 : 1842-1852,2015.
Corrigan-Curay Jacqueline, O'Reilly Marina, Kohn Donald B, Cannon Paula M, Bao Gang, Bushman Frederic D, Carroll Dana, Cathomen Toni, Joung J Keith, Roth David, Sadelain Michel, Scharenberg Andrew M, von Kalle Christof, Zhang Feng, Jambou Robert, Rosenthal Eugene, Hassani Morad, Singh Aparna, Porteus Matthew H: Genome Editing Technologies: Defining a Path to Clinic. Molecular therapy: the journal of the American Society of Gene Therapy 23 (5): 796-806,2015.
Wilson Melissa A, Morrissette Jennifer J D, McGettigan Suzanne, Roth David, Elder David, Schuchter Lynn M, Daber Robert D: What you are missing could matter: a rare, complex BRAF mutation affecting codons 599, 600, and 601 uncovered by next generation sequencing. Cancer genetics : 2014.
Gigi V, Lewis S, Shestova O, Mijušković M, Deriano L, Meng W, Luning Prak ET, Roth DB: RAG2 mutants alter DSB repair pathway choice in vivo and illuminate the nature of 'alternative NHEJ' Nucleic Acids Research 42 (10): 6352-64,2014.
6.036 Gates Building3400 Spruce Street