David A. Mankoff, MD, PhD
Radiology
Accepting new patients
Sees patients age 18 and up
Penn Medicine Provider
About me
- Vice Chair for Research, Radiology
- Matthew J. Wilson Professor of Research Radiology
My education and training
- Medical School: University of Pennsylvania School of Medicine
- Residency: University of Washington Hospitals
Spoken languages
English
English
Insurance accepted
Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.
- Aetna Advantra Cares D-SNP
- Aetna Advantra Credit Value
- Aetna Advantra Eagle HMO
- Aetna Advantra Eagle POS
- Aetna Advantra Premier Plus PPO
- Aetna Advantra Value
- Aetna Advantra Value Plus
- Aetna APCN Plus (Multi-Tier)
- Aetna Better Health Kids (CHIP) - DH Only
- Aetna Flexible Five
- Aetna Freedom Core
- Aetna Gold
- Aetna HMO
- Aetna Philly Prime
- Aetna POS
- Aetna PPO APCN
- Aetna Premier
- Aetna Premier Plus
- Aetna Savings Plus
- Aetna Signature Administrators
- Aetna Student Health Plan PPO
- Aetna Upfront Advantage
- First Health HMO
- First Health POS
- First Health PPO
- Meritain - Aramark (Other)
- Meritain - Aramark (Pennsylvania Premier Medical Plan)
- Americhealth Caritas of PA VIP - LGH Only
- Amerihealth Caritas (Transplant patients only)
- Amerihealth Caritas of PA - LGH Only
- Amerihealth of NJ Core
- Amerihealth of NJ Enhanced
- Amerihealth of NJ HMO
- Amerihealth of NJ Local Value
- Amerihealth of NJ POS
- Amerihealth of NJ PPO
- Amerihealth of NJ Regional Preferred
- Amerihealth of NJ Secure
- Amerihealth of NJ Ultimate (PPO)
- Centivo EPO
- Cigna Healthcare EPO
- Cigna Healthcare HMO
- Cigna Healthcare POS
- Cigna Healthcare PPO
- Claim Watcher (Homestead/ INDECs) Open Access
Locations
Penn Medicine hospital privileges
- Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
- Pennsylvania Hospital: Has privileges to treat patients in the hospital.
- Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
- Chester County Hospital: Has privileges to treat patients in the hospital.
Qualifications and experience
- Nuclear Medicine
- AAMC Training of Physician Scientists (TOPS), National
- American Association for Cancer Research (AACR), National
- American Association for Cancer Research (AACR) Cancer Imaging and Theranostics (CIT) Taskforce, International
- American Society of Clinical Oncology (ASCO), National
- Breastcancer.org, National
- California Breast Cancer Research Program, National
- Canada Foundation for Innovation, International
- Cancer Prevention and Research Institute of Texas (CPRIT), National
- CBICA Advisory Committee, Local
- Centre of Clinical Excellence in the Region of Southern Denmark, International
- Department of Defense Breast Cancer Program, National
- ECOG-ACRIN, National
- German National Center for Tumor Diseases, International
- ITMAT TBIC Pilot Grant Reviewer, Local
- Karmanos Cancer Center, National
- National Cancer Institute (NCI) Cancer Imaging Program, National
- National Institutes of Health (NIH), National
- NIH Public-Private Partnership Study Section, National
- O'Neal Cancer Center, University of Alabama Birmingham, National
- Philadelphia College of Physicians, Local
- Radiologic Society of North America (RSNA), National
- Radiologic Society of North America (RSNA), National
- Radiologic Society of North America (RSNA), National
- Society of Nuclear Medicine (SNM), National
- Society of Nuclear Medicine and Molecular Imaging (SNMMI) and European Association of nuclear Medicine (EANM), International
- Susan G. Komen, National
- Susan G. Komen Foundation, National
- TRACR Advisory Committee, Local
- TransALLTO breast cancer international trial, International
- University of Wisconsin Carbone Cancer Center, National
- Washington University Siteman Cancer Center, National
- Penn Neuroendocrine Tumor Program
- Penn Thyroid and Parathyroid Cancer Program
- Recognized annually in Philadelphia magazine's Top Docs issue from 2023 through 2025
Treatments and conditions
Research
Publications
Sreekumar, A., Blankemeyer, E., Sterner, C. J., Pan, T. C., Pant, D. K., Acolatse, S., Turkistani, H., Belka, G. K., Nayak, A., Carlin, S. D., Assenmacher, C. A., Sellmyer, M. A., Mankoff, D. A., Chodosh, L. A. Residual Breast Cancer Cells Co-opt SOX5-Driven Endochondral Ossification to Maintain Dormancy , Cancer Discov, 16(4): 2026,781-799
Lee, H., Sarkar, S., Xu, K., Martorano, P., Pham, J., Park, P. S. U., King, A. P., Lee, H. S., Mankoff, D. A., Pryma, D. A., Sellmyer, M. A. Influence of Subcellular Localization on the Cytotoxicity of Targeted alpha-Therapy , J Nucl Med, 67(3): 2026,429-437
Chen, A. W., Zeballos Torrez, C. R., Peterson, L. M., Muzi, M., Specht, J. M., Cohen, E. A., Linden, H. M., Kontos, D., Mankoff, D. A. Novel 4D radiomics applied to dynamic FES PET images to improve prediction of breast cancer response to ER-targeted therapy , Eur J Nucl Med Mol Imaging, 53(5): 2026,3128-3139
Choi, H., Gupta, M., Sengupta, A., Furth, E. E., Hensley, C., Weljie, A. M., Lee, H., Lu, Y. T., Pantel, A., Mankoff, D., Zhou, R. Disruption of redox balance in glutaminolytic triple negative breast cancer by inhibition of glutaminase and glutamate export , Neoplasia, 61: 2025,101136
Hensley, C. T., Padakanti, P., Damani, R., Dulal, C., Choi, H., Li, S., Cao, J., Lee, H., Pantel, A., Li, E., Mankoff, D., Zhou, R. L-5-[(11)C]-glutamine PET of breast cancer: Preclinical studies in mouse models , Nucl Med Biol, 150-151: 2025,109092
Kwon, D., Li, E. J., Dulal, C., Daube-Witherspoon, M., Viswanath, V., Young, A. J., Damani, R. A., Hou-Liu, J., McDonald, E. S., Mankoff, D. A., Karp, J. S., Pantel, A. R. Dual-Tracer Imaging on a Long-Axial-Field-of-View PET: A Proof-of-Principle Study with [(18)F]FGln and [(18)F]FDG , J Nucl Med, 66(7): 2025,1149-1152
Mankoff, D., Balogova, S., Dunnwald, L., Dehdashti, F., DeVries, E., Evangelista, L., Van Kruchten, M., Vaz, S. C., Fowler, A., Linden, H., Ulaner, G. A. Summary: SNMMI Procedure Standard/EANM Practice Guideline for Estrogen Receptor Imaging of Patients with Breast Cancer Using 16alpha-[(18)F]Fluoro-17beta-Estradiol PET , J Nucl Med, 65(2): 2024,221-223
Zhou, R., Choi, H., Cao, J., Pantel, A., Gupta, M., Lee, H. S., Mankoff, D. (18)F-Fluciclovine PET Imaging of Glutaminase Inhibition in Breast Cancer Models , J Nucl Med, 64(1): 2023,131-136
Pantel, A. R., Gitto, S. B., Makvandi, M., Kim, H., Medvedv, S., Weeks, J. K., Torigian, D. A., Hsieh, C. J., Ferman, B., Latif, N. A., Tanyi, J. L., Martin, L. P., Lanzo, S. M., Liu, F., Cao, Q., Mills, G. B., Doot, R. K., Mankoff, D. A., Mach, R. H., Lin, L. L., Simpkins, F. [18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study , Clin Cancer Res, 29(8): 2023,1515-1527
McDonald, E. S., Doot, R. K., Pantel, A. R., Farwell, M. D., Mach, R. H., Maxwell, K. N., Mankoff, D. A. Positron Emission Tomography Imaging of Poly-(Adenosine Diphosphate-Ribose) Polymerase 1 Expression in Breast Cancer: A Nonrandomized Clinical Trial , JAMA Oncol: 2020