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Adults (18-65), Geriatrics (65+)
Adults (18-65), Geriatrics (65+)
Does not see patients
My clinical expertise is in Laboratory Medicine, Cardiac Biomarkers, Clinical Chemistry, and Pathology Informatics.
My research interests are in the pragmatic prediction of disease and in developing systems to improve the interpretation of clinical laboratory results. Current areas of research include:1) Leveraging electronic health record data to screen for underdiagnosed diseases, including secondary hypertension2) Developing and implementing computational tools to improve the quality of clinical laboratory results and facilitate context-dependent interpretation3) Improving the prediction of primary cardiovascular disease by assessing the gap between existing biomarkers and the clinical needs
Lingjiao Zhang, Xiruo Ding, Yanyuan Ma, Naveen Muthu, Imran Ajmal, Jason H. Moore, Daniel S. Herman*, Jinbo Chen*; * Co-corresponding: A maximum likelihood approach to electronic health record phenotyping using positive and unlabeled patients J Am Med Inform Assoc. 27 (1): 2020.
Daniel S Herman, Eseraldo Toro, Ezra G. Baraban, Adam Bagg, Ping Wang: Falsely Increased Plasma Lactate Dehydrogenase without Hemolysis Following Transport Through Pneumatic Tube System JALM : 2019.
Herman DS, Smith C, Liu C, Vaughn CP, Palaniappan S, Pritchard CC, Shirts BH: Efficient Detection of Copy Number Mutations in PMS2 Exons with Close Homologs: Detection of Copy Number Variants in 3' PMS2 Exons J Mol Diagn 20 (4): 512-521,2018.
Herman DS, Ranjitkar P, Yamaguchi D, Grenache DG, Greene DN.: Endogenous alkaline phosphatase interference in cardiac troponin I and other sensitive chemiluminescence immunoassays that use alkaline phosphatase activity for signal amplification. Clin Biochem 49 (15): 1118-1121,2016.
Roberts AM*, Ware JS*, Herman DS*, Schafer S, Baksi J, Bick AG, Buchan RJ, Walsh R, John S, Wilkinson S, Mazzarotto F, Felkin LE, Gong S, MacArthur JA, Cunningham F, Flannick J, Gabriel SB, Altshuler DM, Macdonald PS, Heinig M, Keogh AM, Hayward CS, Banner NR, Pennell DJ, O'Regan DP, San TR, de Marvao A, Dawes TJ, Gulati A, Birks EJ, Yacoub MH, Radke M, Gotthardt M, Wilson JG, O'Donnell CJ, Prasad SK, Barton PJ, Fatkin D, Hubner N, Seidman JG, Seidman CE, Cook SA.: Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease. Sci Transl Med 7 (270): 270ra6,2015.
Bick AG, Flannick J, Ito K, Cheng S, Ramachandran VS, Parfenov MG, Herman DS, DePalma SR, Gupta N, Gabriel S, Funke BH, Rehm HL, Benjamin E, Aragam J, Taylor HA, Fox ER, Newton-Cheh C, Kathiresan S, O’Donnell C, Wilson JG, Altshuler DL, Hirschhorn JN, Seidman JG, Seidman C.: Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study Cohorts. Am J Hum Gen 91 (3): 513-9,2012.
Herman DS, Lam L, Taylor MR, Wang L, Teekakirikul P, Christodoulou D, Conner L, DePalma SR, McDonough B, Sparks E, Teodorescu DL, Cirino AL, Banner NR, Pennell DJ, Graw S, Merlo M, Di Lenarda A, Sinagra G, Bos JM, Ackerman MJ, Mitchell RN, Murry CE, Lakdawala NK, Ho CY, Barton PJ, Cook SA, Mestroni L, Seidman JG, Seidman CE.: Truncations of Titin Causing Dilated Cardiomyopathy. N Engl J Med. 366 (7): 619-28,2012.
Herman DS, Hovingh GK, Iartchouk O, Rehm HL, Kucherlapati R, Seidman JG, Seidman CE.: Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection. Nat Methods 6 (7): 507-10,2009.
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