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Clyde E. Markowitz, MD

Clyde E. Markowitz, MD Physician

Director, Multiple Sclerosis Center at Penn Associate Professor of Neurology at the Hospital of the University of Pennsylvania

Dr. Markowitz is employed by Penn Medicine.

About Dr. Clyde E. Markowitz

Recognized by America's Top Doctors 2015 – 2017

Recognized by Best Doctors in America 2015 - 2018

Recognized in Philadelphia magazine's annual Top Docs issues for 2018 and 2019

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties

Specialty:

  • Neurology

Programs & Centers:

Board Certification:

  • Neurology, 1995

Clinical Expertise:

  • Abnormal Reflexes
  • Alzheimer's Disease
  • Arm Weakness
  • Arteriovenous Malformations (AVM)
  • Ataxia
  • Bell's Palsy
  • Benign Paroxysmal Positional Vertigo
  • Carotid Stenosis
  • Cerebellar Ataxia
  • Cerebellar Disease
  • Cerebral Aneurysm
  • Cerebrovascular Accident
  • Cervical Dystonia
  • Charcot Marie Tooth Disease (CMT)
  • CNS Vasculitis
  • Cognitive Impairment
  • Concussion
  • Cranial Nerve Injuries
  • Encephalopathies
  • Epilepsy
  • Facial Droop
  • Facial Nerve Pain (Neuralgia)
  • Facial Pain
  • Guillain-Barré Syndrome (GBS)
  • Headache
  • Leg Weakness
  • Lip Droop
  • Lobar Atrophy of Brain
  • Medication Overuse Headache
  • Memory Disorders
  • Movement Disorders
  • Multiple Sclerosis (MS)
  • Muscle Weakness
  • Myasthenia Gravis (MG)
  • Myelitis
  • Nerve Root Pain
  • Nervous System Disorders
  • Neuromuscular Disorders
  • Neuropathy
  • Nonruptured Cerebral Aneurysm
  • Orthostatic Hypotension
  • Paraplegia
  • Paresthesia
  • Parkinson's Disease
  • Peripheral Nerve Disorders
  • Peripheral Neuropathy
  • Periventricular Leukomalacia
  • Positional Vertigo
  • Primary Cerebellar Degeneration
  • Primary Progressive Aphasia
  • Pseudotumor Cerebri
  • Quadriplegia
  • Radiculopathy
  • Sensory Impairment
  • Spinocerebellar Ataxia
  • Spinocerebellar Degeneration
  • Spinocerebellar Diseases
  • Stroke
  • Subarachnoid Hemorrhage
  • Syncope
  • Tetraplegia
  • Tinnitus
  • Torticollis
  • Transient Ischemic Attack
  • Traumatic Brain Injury (TBI)
  • Tremor
  • Trigeminal Nerve Disorders
  • Trigeminal Neuralgia (Tic Douloureux)
  • Unsteady Gait
  • Vertigo
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Columbia University
Residency: NewYork-Presbyterian/Columbia University Medical Center
Fellowship: NewYork-Presbyterian/Columbia University Medical Center

Memberships

American Academy of Neurology, National American Academy of Neurology, National Bayer Healthcare, International Biogen-Idec, International BioMS, International Bristol Meyers Squib, International EMD Serono, International Genentech, International International Multiple Sclerosis Forum, International Multiple Sclerosis Cooperative Research Group (MS-CORE), National National Multiple Sclerosis Society, Delaware Valley Chapter, Local Novartis, International Penn Neuro Care-MS Section, Local Pfizer, International Teva Neuroscience, International Wyeth, International

Hospital Affiliation

Dr. Markowitz is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Selected Publications:

Fox EJ, Markowitz C, Applebee A, Montalban X, Wolinsky JS, Belachew S, Fiore D, Pei J, Musch B, Giovannoni G: Ocrelizumab reduces progression of upper extremity impairment in patients with primary progressive multiple sclerosis: Findings from the phase III randomized ORATORIO trial. Mult Scler. : 2018.

Cehelyk EK, Harvey DY, Grubb ML, Jalel R, El-Sibai MS, Markowitz CE, Berger JR, Hamilton RH, Chahin S: Uncovering the association between fatigue and fatigability in multiple sclerosis using cognitive control. Mult Scler Relat Disord. 27 : 269-275,2018.

Fox E, Markowitz C, Applebee A, et al: Effect of ocrelizumab on upper limb function in patients with primary progressive multiple sclerosis (PPMS) in the oratorio study (ENCORE) J Neurol Neurosurg Psychiatry 89 (A14): 2018.

Sahin N, Selouan R, Markowitz CE, Melhem ER, Bilello M: Limbic pathway lesions in patients with multiple sclerosis. Acta Radiol. 57 (3): 341-7,2016.

Salim Chahin, MD; Deborah Miller, PhD; Reiko Sakai; James Wilson; Clyde Markowitz, MD; Dina Jacobs, MD; Ari Green, MD; Peter A. Calabresi, MD; Elliot M. Frohman, MD; Steven Galetta, MD; Laura Balcer, MD, MSCE:: Fatigue in Multiple Sclerosis: Relation to Quantitative Neurologic and Visual Outcomes. Multiple Sclerosis and related disorders : 2015.

Jose Torres, Amy Pruitt, Laura Balcer, Steven Galetta, Clyde Markowitz, Nabila Dahodwala: Analysis of the treatment of neuromyelitis optica Journal of the Neurological Sciences 351 (1): 2015.

Salim Chahin, Deborah Miller, Reiko E. Sakai, James A. Wilson, Teresa Frohman, Clyde Markowitz, Dina Jacobs, Ari Green, Peter A. Calabresi, Elliot M. Frohman, Steven L. Galetta, Laura J. Balcer: Relation of quantitative Visual and neurologic outcomes to fatigue in multiple sclerosis Multiple Sclerosis and Related Disorders 4 (4): 2015.

Edward Fox, Barbara Green, Clyde Markowitz, Ronald Murray, Andrew D Goodman, Stephen J Glenski, Pippa Loupe, Jo Nita Cogburn: The effect of scheduled antibody testing on treatment patterns in interferon-treated patients with multiple sclerosis BMC Neurology 14 (1): 2014.

Patricia K Coyle, Bruce A Cohen, Thomas Leist, Clyde Markowitz, Merrikay Oleen-Burkey, Marc Schwartz, Mark J Tullman, Howard Zwibel: Therapy optimization in multiple sclerosis: a prospective observational study of therapy compliance and outcomes BMC Neurology 14 (1): 2014.

Miller Aaron E, Cohen Bruce A, Krieger Stephen C, Markowitz Clyde E, Mattson David H, Tselentis Helen N: Constructing an adaptive care model for the management of disease-related symptoms throughout the course of multiple sclerosis--performance improvement CME. Multiple sclerosis (Houndmills, Basingstoke, England) : 2013.

Academic Contact Info

Hospital of the University of Pennsylvania
3 West Gates Building
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 662-4521
Patient appointments: 800-789-7366 (PENN)

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